Rchr
J-GLOBAL ID：201601007524330090   Update date: Dec. 09, 2025

Yohei Hayashi

ハヤシ ヨウヘイ | Yohei Hayashi
Affiliation and department：
CiRA Foundation Research and Development Center

About CiRA Foundation Research and Development Center


Job title： Unit Leader
Homepage URL  (1)： https://scholar.google.com/citations?view_op=list_works&hl=en&user=NIoDH4AAAAAJ
Research field  (2)： Medical biochemistry ,  Cell biology
Research keywords  (7)： induced pluripotent stem cells ,  Embryonic Stem cells ,  Cellular Reprogramming ,  Differentiation ,  Disease Modeling ,  Reprogramming ,  iPS Cells
Research theme for competitive and other funds  (26)：
  • 2025 - 2028 次世代リプログラミング因子を用いた完全浮遊培養系でのバルクダイレクトiPS細胞
  • 2025 - 2028 Functional analysis of hepatic stellate cells using biliary atresia-specific iPS cells and basic research toward suppressing liver fibrosis
  • 2024 - 2027 Genomic conformational changes in a pathological model using iPS cells derived from patients with chromosome deletion syndrome
  • 2024 - 2027 Research for the Pathological Understanding and Therapeutic Development of SIFD Using iPS Cells
  • 2023 - 2026 Cell fate decision by dose of transcription factors
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Papers (74)：
  • Yuichi Akaba, Satoru Takahashi, Shota Adachi, Masatoshi Nishimura, Keiichiro Suzuki, Hideyuki Nakashima, Kinichi Nakashima, Ryutaro Kira, Pin Fee Chong, Yasunari Sakai, et al. miR-199a functions downstream of MeCP2 in neurons of MECP2 duplication syndrome models. iScience. 2025. 28. 11. 113789-113789
  • Seiichiro Honda, Taketaro Sadahiro, Yuto Abe, Yu Yamada, Tatsuya Akiyama, Koji Nakano, Tomohiko C Umei, Masashi Nakamura, Takashi Maeda, Hisashi Okada, et al. Shortening and optimization of MEF2C and GATA4 promote cardiac reprogramming. Biochemical and biophysical research communications. 2025. 781. 152511-152511
  • Tomoya Shimizu, Miho Takami, Mami Matsuo-Takasaki, Michiya Noguchi, Yukio Nakamura, Tadayoshi Hayata, Yohei Hayashi. Generation of human induced pluripotent stem cell lines derived from Wolf-Hirschhorn syndrome patients with chromosomal 4p deletion. Human cell. 2025. 38. 6. 164-164
  • Yohei Hayashi, Junichi Matsumoto, Kimio Sumaru. Micropatterned neural induction with heat-inactivated extracellular matrix protein by on-demand high-speed laser. 2025
  • Slo-Li Chu, Kuniya Abe, Yi-Hsuan Li, Yohei Hayashi, Hideo Yokota, Daigo Takagi, Silvia Natsuko Akutsu, Shinya Matsuura, Tadayoshi Hayata, Ming-Dar Tsai. Deep Learning Method for Classifying Spatial Patterning of Early Differentiated Human Induced Pluripotent Stem Cells using Micropattern Images. Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference. 2025. 2025. 1-4
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MISC (21)：
  • 鈴木完, 林洋平, 木戸丈友, 谷水直樹, 藤代準, 小嶋一幸. iPS細胞を用いた胆道閉鎖症病態解明へ向けた研究の現状と課題. 日本外科学会定期学術集会(Web). 2025. 125th
  • 越後谷健太, 滝沢由政, 鯨井智也, 小笠原光雄, 林洋平, 胡桃坂仁志. ゲノム配列ヌクレオソームに対するパイオニア転写因子SOX2の結合機構. 日本生化学会大会(Web). 2024. 97th
  • 林洋平. バイオリソースとしてのiPS細胞の利活用. 日本分子生物学会年会プログラム・要旨集(Web). 2024. 47th
  • 高崎真美, 神林昌, 清水智哉, 河井義和, 中石智之, 加藤智朗, 梅影雅史, 塚原政義, 林洋平. Complete suspension culture of iPSCs supplemented with suppressor of spontaneous differentiation. 組織培養研究(Web). 2024. 42. 2
  • 野口道也, 井上循, 岡田奈緒子, 林洋平, 中村幸夫. Testing for residual episomal vectors in iPSCs by qPCR. 組織培養研究(Web). 2024. 42. 2
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Patents (4)：
Books (6)：
  • 培養細胞が拓く創薬の今 -研究、規制、自動化、そして教育へ-
    (株)シーエムシー・リサーチ 2025 ISBN:9784910581644
  • 動物実験代替法とNew approach methodologiesの開発・利用動向
    シーエムシー出版 2023 ISBN:9784781317472
  • 細胞培養・組織培養の技術
    朝倉書店 2023 ISBN:9784254310962
  • 細胞培養実習テキスト 第2版
    じほう 2020 ISBN:9784840752923
  • ~医薬品・再生医療製品開発者・技術者のための~iPS細胞の最新技術開発
    技術情報協会 2016
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Lectures and oral presentations  (6)：
  • iPS細胞における環状染色体の自己修復
    (第16回日本再生医療学会総会 2017)
  • Structure-based Discovery of NANOG Variant with Enhanced Properties to Promote Self-Renewal and Reprogramming of Pluripotent Stem Cells
    (第39回日本分子生物学会大会 2016)
  • 光応答性材料を介した光照射によるiPS細胞の分化操作
    (第8回TIAシンポジウム 2016)
  • Cell-Autonomous Correction of Ring Chromosomes in Human Induced Pluripotent Stem Cells
    (TERMIS (Tissue Engineering and Regenerative Medicine International Society) -AP (Asia & Pacific) 2016 2016)
  • 転写因子の構造解析から多能性幹細胞・リプログラミング機構の解明へ
    (生命の機能とかたち 筑波大学&高エネルギー加速器研究機構 第1回連携セミナー 2016)
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Education (3)：
  • 2004 - 2009 The University of Tokyo Graduate School of Arts and Sciences Multi-Disciplinary Sciences Life Sciences
  • 2000 - 2004 The University of Tokyo, College of Arts and Sciences
  • 1997 - 2000 Okazaki High School
Professional career (1)：
  • Ph. D. (University of Tokyo)
Work history (8)：
  • 2024/12 - 現在 CiRA Foundation Research and Development Center Unit Leader
  • 2022/07 - 2024/11 University of Tsukuba School of Integrative and Global Majors Professor
  • 2018/04 - 2024/11 RIKEN Bioresource Research Center Team Leader
  • 2016/04 - 2018/03 University of Tsukuba Graduate School of Comprehensive Human Sciences Assistant Professor
  • 2015/01 - 2015/03 Research Scientist at Gladstone Institute of Cardiovascular Disease
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Committee career (13)：
  • 2025/06 - 現在 日本再生医療学会 U45(若手研究者のワーキンググループ) 座長
  • 2025/06 - 現在 日本再生医療学会 理事長補佐
  • 2025/04 - 現在 日本再生医療学会 広報委員会 委員
  • 2025/01 - 現在 Discover Developmental Biology Editorial Board Member
  • 2025/01 - 現在 Human Cell Editorial Board Member
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Awards (12)：
  • 2025/06 - Springer Nature Springer Nature Editor of Distinction Award 2025
  • 2024/01 - Tsukuba Center, inc. Excellent Award, Seeds Category, 4th TCI Venture Award
  • 2019/11 - The Science and technology Promotion Foundation of Ibaraki Tsukuba Encouragement Prize Young Researchers
  • 2018/04 - 筑波大学 筑波大学 若手教員特別奨励賞
  • 2018/04 - 文部科学省 平成30年度科学技術分野の文部科学大臣表彰 若手科学者賞
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Association Membership(s) (6)：
バイオインダストリー協会 ,  THE MOLECULAR BIOLOGY SOCIETY OF JAPAN ,  THE JAPANESE TISSUE CULTURE ASSOCIATION ,  THE JAPANESE SOCIETY FOR REGENERATIVE MEDICINE ,  International Society for Stem Cell Research (ISSCR) ,  Tissue Engineering and Regenerative Medicine International Society (TERMIS)
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