Yohei Hayashi

ハヤシヨウヘイ | Yohei Hayashi

Affiliation and department：
Job title： Unit Leader
Homepage URL (1)： https://scholar.google.com/citations?view_op=list_works&hl=en&user=NIoDH4AAAAAJ

Research field (2)： Medical biochemistry , Cell biology

Research keywords (7)： induced pluripotent stem cells , Embryonic Stem cells , Cellular Reprogramming , Differentiation , Disease Modeling , Reprogramming , iPS Cells

Research theme for competitive and other funds (23)：

2024 - 2027 Research for the Pathological Understanding and Therapeutic Development of SIFD Using iPS Cells
2023 - 2026 Cell fate decision by dose of transcription factors
2021 - 2025 Phenotypic screening of genome-edited Induced pluripotent stem cells
2021 - 2024 22q11.2症候群特異的iPS細胞由来神経堤の病態モデルでのゲノム編集応用
2020 - 2023 胆道閉鎖症特異的iPS細胞を用いた胆管発生およびその障害メカニズムの解明

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Papers (70)：

Yohei Hayashi, Junichi Matsumoto, Kimio Sumaru. Micropatterned neural induction with heat-inactivated extracellular matrix protein by on-demand high-speed laser. 2025
Rui Li, Hazuki Tsuboi, Hidenori Ito, Daigo Takagi, Yun-Hsuan Chang, Tomoya Shimizu, Yutaka Arai, Mami Matsuo-Takasaki, Michiya Noguchi, Yukio Nakamura, et al. Generation of human induced pluripotent stem cell lines derived from two glucose transporter 1 deficiency syndrome patients. Stem Cell Research. 2024. 81. 103584-103584
Ningxin Ge, Kan Suzuki, Iori Sato, Michiya Noguchi, Yukio Nakamura, Mami Matsuo-Takasaki, Jun Fujishiro, Yohei Hayashi. Generation of human induced pluripotent stem cell lines derived from patients of cystic biliary atresia. Human cell. 2024. 38. 1. 18-18
Mami Matsuo-Takasaki, Sho Kambayashi, Yasuko Hemmi, Tamami Wakabayashi, Tomoya Shimizu, Yuri An, Hidenori Ito, Kazuhiro Takeuchi, Masato Ibuki, Terasu Kawashima, et al. Complete suspension culture of human induced pluripotent stem cells supplemented with suppressors of spontaneous differentiation. eLife. 2024. 12. 12. RP89724
Slo-Li Chu, Kuniya Abe, Hideo Yokota, Dooseon Cho, Yohei Hayashi, Ming-Dar Tsai. Deep learning for quantifying spatial patterning and formation process of early differentiated human-induced pluripotent stem cells with micropattern images. Journal of microscopy. 2024. 296. 1. 79-93

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MISC (19)：

林洋平. バイオリソースとしてのiPS細胞の利活用. 日本分子生物学会年会プログラム・要旨集(Web). 2024. 47th
高崎真美, 神林昌, 清水智哉, 河井義和, 中石智之, 加藤智朗, 梅影雅史, 塚原政義, 林洋平. Complete suspension culture of iPSCs supplemented with suppressor of spontaneous differentiation. 組織培養研究(Web). 2024. 42. 2
野口道也, 井上循, 岡田奈緒子, 林洋平, 中村幸夫. Testing for residual episomal vectors in iPSCs by qPCR. 組織培養研究(Web). 2024. 42. 2
伊藤秀矩, 佐藤伊織, 辺見康子, 若林玲実, 高崎真美, 野口道也, 中村幸夫, 林洋平. Development of a disease model for von Hippel-Lindau syndrome using patient-specific iPS cells. 組織培養研究(Web). 2024. 42. 2
林洋平, 若林玲実, 松本潤一, 高崎真美, 須丸公雄. Effects of cell adhesion patterning in laser irradiation-ECM inactivation on neural induction from human iPS cells. 組織培養研究(Web). 2024. 42. 2

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Books (6)：

培養細胞が拓く創薬の今 -研究、規制、自動化、そして教育へ-
(株)シーエムシー・リサーチ 2025 ISBN:9784910581644
動物実験代替法とNew approach methodologiesの開発・利用動向
シーエムシー出版 2023 ISBN:9784781317472
細胞培養・組織培養の技術
朝倉書店 2023 ISBN:9784254310962
細胞培養実習テキスト第2版
じほう 2020 ISBN:9784840752923
~医薬品・再生医療製品開発者・技術者のための~iPS細胞の最新技術開発
技術情報協会 2016

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Lectures and oral presentations (6)：

iPS細胞における環状染色体の自己修復
(第16回日本再生医療学会総会 2017)
Structure-based Discovery of NANOG Variant with Enhanced Properties to Promote Self-Renewal and Reprogramming of Pluripotent Stem Cells
(第39回日本分子生物学会大会 2016)
光応答性材料を介した光照射によるiPS細胞の分化操作
(第8回TIAシンポジウム 2016)
Cell-Autonomous Correction of Ring Chromosomes in Human Induced Pluripotent Stem Cells
(TERMIS (Tissue Engineering and Regenerative Medicine International Society) -AP (Asia & Pacific) 2016 2016)
転写因子の構造解析から多能性幹細胞・リプログラミング機構の解明へ
(生命の機能とかたち筑波大学&高エネルギー加速器研究機構第1回連携セミナー 2016)

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Education (3)：

2004 - 2009 The University of Tokyo Graduate School of Arts and Sciences Multi-Disciplinary Sciences Life Sciences
2000 - 2004 The University of Tokyo, College of Arts and Sciences
1997 - 2000 Okazaki High School

Professional career (1)：

Ph. D. (University of Tokyo)

Work history (8)：

2024/11 - 現在 CiRA Foundation Research and Development Center Unit Leader
2022/07 - 2024/11 University of Tsukuba School of Integrative and Global Majors Professor
2018/04 - 2024/11 RIKEN Bioresource Research Center Team Leader
2016/04 - 2018/03 University of Tsukuba Graduate School of Comprehensive Human Sciences Assistant Professor
2015/01 - 2015/03 Research Scientist at Gladstone Institute of Cardiovascular Disease

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Committee career (10)：

2025/04 - 現在日本再生医療学会広報委員会委員
2025/01 - 現在 Discover Developmental Biology Editorial Board Member
2025/01 - 現在 Human Cell Editorial Board Member
2023/04 - 現在バイオインダストリー協会バイオエンジニアリング研究会委員
2021/06 - 現在日本再生医療学会チームU45 メンバー

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Awards (12)：

2025/06 - Springer Nature Springer Nature Editor of Distinction Award 2025
2024/01 - Tsukuba Center, inc. Excellent Award, Seeds Category, 4th TCI Venture Award
2019/11 - The Science and technology Promotion Foundation of Ibaraki Tsukuba Encouragement Prize Young Researchers
2018/04 - 筑波大学筑波大学若手教員特別奨励賞
2018/04 - 文部科学省平成30年度科学技術分野の文部科学大臣表彰若手科学者賞

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Association Membership(s) (6)：

バイオインダストリー協会 , THE MOLECULAR BIOLOGY SOCIETY OF JAPAN , THE JAPANESE TISSUE CULTURE ASSOCIATION , THE JAPANESE SOCIETY FOR REGENERATIVE MEDICINE , International Society for Stem Cell Research (ISSCR) , Tissue Engineering and Regenerative Medicine International Society (TERMIS)

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