Yohei Hayashi

ハヤシヨウヘイ | Yohei Hayashi

Affiliation and department：
Job title： Team Leader (Principal Investigator)
Homepage URL (2)： https://acd.brc.riken.jp/ja/ , http://www.riken.jp/research/labs/brc/ips_cell_adv_char_dev/

Research field (2)： Medical biochemistry , Cell biology

Research keywords (7)： induced pluripotent stem cells , Embryonic Stem cells , Cellular Reprogramming , Differentiation , Disease Modeling , Reprogramming , iPS Cells

Research theme for competitive and other funds (19)：

2020 - 2023 胆道閉鎖症特異的iPS細胞を用いた胆管発生およびその障害メカニズムの解明
2019 - 2022 iPS細胞誘導におけるKlf4を中心とした動的エピゲノム転写制御の分子機構
2017 - 2021 Reprogramming of cell morphology and functions by Klf4 during iPSC generation
2017 - 2021 染色体異常を伴った疾患特異的iPS細胞を修復する「染色体編集法」の開発
2016 - 2018 KLF4DNA結合部位アミノ酸残基の機能解析から改良リプログラミング因子の開発

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Papers (37)：

Yuji Kuramochi, Tomonari Awaya, Mami Matsuo-Takasaki, Miho Takami, Yuri An, Jingyue Li, Yasuko Hemmi, Tamami Wakabayashi, Yutaka Arai, Jun Inoue, et al. Generation of two human induced pluripotent stem cell lines derived from two X-linked adrenoleukodystrophy patients with ABCD1 mutations. Stem cell research. 2021. 53. 102337-102337
Satomi Tsukamoto, Koji Nakade, Tamami Wakabayashi, Kenichi Nakashima, Miho Takami, Yasuko Hemmi, Yuji Kuramochi, Tomoya Shimizu, Yutaka Arai, Mami Matsuo-Takasaki, et al. Generation of two ISL1-tdTomato reporter human induced pluripotent stem cell lines using CRISPR-Cas9 genome editing. Stem cell research. 2021. 53. 102363-102363
Generation of two human induced pluripotent stem cell lines derived from two juvenile nephronophthisis patients with NPHP1 deletion. Stem Cell Research. 2020. 45. 101815
Yohei Hayashi, Miho Takami, Mami Matsuo-Takasaki. Studying Abnormal Chromosomal Diseases Using Patient-Derived Induced Pluripotent Stem Cells. Frontiers in cellular neuroscience. 2020. 14. 224-224
Bui PL, Nishimura K, Seminario Mondejar G, Kumar A, Aizawa S, Murano K, Nagata K, Hayashi Y, Fukuda A, Onuma Y, et al. Template Activating Factor-I α Regulates Retroviral Silencing during Reprogramming. Cell reports. 2019. 29. 7. 1909-1922.e5

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MISC (1)：

Hayashi Y, Hsiao E, Sami S, Lancero M, Schlieve C, Yano K, Nagahashi A, Ikeya M, Matsumoto Y, Asaka I, et al. BMP-SMAD-ID axis promotes reprogramming to pluripotency. 第10 回ISSCR(2012.6.14.横浜). 2012

Books (3)：

細胞培養実習テキスト第2版
じほう 2020 ISBN:9784840752923
~医薬品・再生医療製品開発者・技術者のための~iPS細胞の最新技術開発
技術情報協会 2016
細胞培養・品質管理の基礎知識と細胞培養基材の利用・開発・評価の留意点
情報機構 2016

Lectures and oral presentations (6)：

iPS細胞における環状染色体の自己修復
(第16回日本再生医療学会総会 2017)
Structure-based Discovery of NANOG Variant with Enhanced Properties to Promote Self-Renewal and Reprogramming of Pluripotent Stem Cells
(第39回日本分子生物学会大会 2016)
光応答性材料を介した光照射によるiPS細胞の分化操作
(第8回TIAシンポジウム 2016)
Cell-Autonomous Correction of Ring Chromosomes in Human Induced Pluripotent Stem Cells
(TERMIS (Tissue Engineering and Regenerative Medicine International Society) -AP (Asia & Pacific) 2016 2016)
転写因子の構造解析から多能性幹細胞・リプログラミング機構の解明へ
(生命の機能とかたち筑波大学&高エネルギー加速器研究機構第1回連携セミナー 2016)

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Education (3)：

2004 - 2009 The University of Tokyo Multi-Disciplinary Sciences Life Sciences
2000 - 2004 The University of Tokyo, College of Arts and Sciences
1997 - 2000 Okazaki High School

Professional career (1)：

Ph. D. (University of Tokyo)

Work history (6)：

2018/04 - 現在 RIKEN Bioresource Research Center Team Leader
2016/04 - 2018/03 University of Tsukuba Graduate School of Comprehensive Human Sciences Assistant Professor
2015/01 - 2015/03 Research Scientist at Gladstone Institute of Cardiovascular Disease
2014/07 - 2015/03 Postdoctoral Fellow Overseas, Japanese Society for Promoting Sciences
2009/05 - 2014/12 Gladstone Institute of Cardiovascular Disease

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Committee career (5)：

2018/11 - 現在日本再生医療学会代議員
2021/06 - 日本再生医療学会チームU45 メンバー
2021/04 - 日本組織培養学会理事
2017/04 - 日本組織培養学会幹事(会計)
2016/05 - 日本組織培養学会第89回大会運営委員副委員長

Awards (10)：

2019/11 - The Science and technology Promotion Foundation of Ibaraki Tsukuba Encouragement Prize Young Researchers
2018/04 - 筑波大学筑波大学若手教員特別奨励賞
2018/04 - 文部科学省平成30年度科学技術分野の文部科学大臣表彰若手科学者賞
2017/12 - 筑波大学若手教員奨励賞
2014/01 - 7th Takeda Science Foundation Symposium on PharmaScience Excellent Poster Award, 7th Takeda Science Foundation Symposium on PharmaScience

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Association Membership(s) (5)：

THE MOLECULAR BIOLOGY SOCIETY OF JAPAN , THE JAPANESE TISSUE CULTURE ASSOCIATION , THE JAPANESE SOCIETY FOR REGENERATIVE MEDICINE , International Society for Stem Cell Research (ISSCR) , Tissue Engineering and Regenerative Medicine International Society (TERMIS)

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