Rchr
J-GLOBAL ID:201601009146057366   Update date: Aug. 23, 2024

Yamaguchi Shinpei

ヤマグチ シンペイ | Yamaguchi Shinpei
Affiliation and department:
Job title: Lecturer
Homepage URL  (2): https://www.lab.toho-u.ac.jp/sci/bio/reprogramming/index.htmlhttps://www.lab.toho-u.ac.jp/sci/bio/reprogramming/en/index.html
Research field  (3): Laboratory animal science ,  Molecular biology ,  Developmental biology
Research keywords  (9): リプログラミング ,  DNAメチル化/脱メチル化 ,  全能性 ,  生殖細胞 ,  ゲノムインプリンティング ,  ES細胞 ,  初期胚 ,  エピジェネティクス ,  幹細胞
Research theme for competitive and other funds  (6):
  • 2022 - 2025 The Role of Genomic Imprinting in the Brain
  • 2019 - 2024 全能性消失時のエピゲノム制御機構の解明
  • 2019 - 2023 多能性幹細胞における異なる分化状態の動的維持機構
  • 2016 - 2019 Role of genomic imprinting in the establishment of ESCs
  • 2016 - 2018 始原生殖細胞特異的なヘテロクロマチン動態の解析
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Papers (26):
  • Takamasa Ito, Musashi Kubiura-Ichimaru, Fumihito Miura, Shoji Tajima, M. Azim Surani, Takashi Ito, Shinpei Yamaguchi, Masako Tada. DNMT1 can induce primary germ layer differentiation through de novo DNA methylation. Genes to Cells. 2024
  • Tomoka Katayama, Marina Takechi, Yamato Murata, Yuta Chigi, Shinpei Yamaguchi, Daiji Okamura. Development of a chemically disclosed serum-free medium for mouse pluripotent stem cells. Frontiers in bioengineering and biotechnology. 2024. 12. 1390386-1390386
  • Kit-Yeng Sheng, Toru Nakano, Shinpei Yamaguchi. A region-dependent allele-biased expression of Dopa decarboxylase in mouse brain. Frontiers in cell and developmental biology. 2022. 10. 1078927-1078927
  • Maeda Takahiro, Yasuyoshi Kimura, Toru Nakano, Shinpei Yamaguchi. Ribosomal stress induces 2-cell embryo-like state transition of the mouse ESCs through p53 activation. Biochemical and biophysical research communications. 2021. 579. 175-180
  • Yota Hagihara, Satoshi Asada, Takahiro Maeda, Toru Nakano, Shinpei Yamaguchi. Tet1 regulates epigenetic remodeling of the pericentromeric heterochromatin and chromocenter organization in DNA hypomethylated cells. PLoS genetics. 2021. 17. 6. e1009646
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MISC (15):
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Books (2):
  • 誰でも再現できるNGS「前」サンプル調製プロトコール : 生物種別DNA、RNA、クロマチン、シングルセル調製の極意
    羊土社 2024 ISBN:9784758122726
  • エピジェネティクス実験スタンダード : もう悩まない!ゲノム機能制御の読み解き方
    羊土社 2017 ISBN:9784758101998
Lectures and oral presentations  (24):
  • Stress-induced transition of mouse ESCs to a two-cell embryo-like state
    (The 5th Open Symposium of the New Academic Research Area Totipotency Program 2023)
  • Development of Tissue Cell Experimental Systems for Building Novel Drug Discovery Platforms
    (12th Joint Seminar on Biomedical Sciences 2023)
  • Understanding the Role of Genomic Imprinting: Exploring the physiological functions and molecular mechanisms in mice and stem cell models
    (2023 Symposium on Epigenetic Regulation 2023)
  • Epigenomes erased and imprinted in germ cells: regulatory mechanisms and functions.
    (2023)
  • マウス脳におけるインプリンティングの可視化と機能解明
    (第45回日本分子生物学会年会 2022)
more...
Work history (6):
  • 2022/04 - 現在 Toho University Faculty of Science Department of Biology Lecturer
  • 2015/06 - 2022/03 大阪大学大学院・医学系研究科
  • 2012/08 - 2015/05 ハーバード医科大学・ボストン小児病院
  • 2013/04 - 2015/03 日本学術振興会・海外特別研究員(兼任)
  • 2011/05 - 2012/07 ノースカロライナ大学チャペルヒル校
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Awards (3):
  • 2013/03 - Department of Genetics, Harvard Medical School Department of Genetics Retreat award at Retreat of Harvard Medical School
  • 2013/03 - Best Poster award at Epigenetics & Chromatin Interactions and processes conference
  • 2008/11 - 第23回内藤コンファレンス ベストポスター賞
Association Membership(s) (3):
日本分子生物学会 ,  日本遺伝学会 ,  日本エピジェネティクス研究会
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