DAISUKE SHIRAISHI

シライシダイスケ | DAISUKE SHIRAISHI

Affiliation and department：

Research field (1)： Orthopedics

Research theme for competitive and other funds (4)：

2022 - 2025 肉腫の転移に関わる免疫微小環境を標的とした新規治療法の開発
2019 - 2022 Elucidation of the function of CD163-positive macrophages in the tumor microenvironment.
2016 - 2019 Studies on the function of CD163, a macrophage scavenger receptor, in tumor microenvironment
2016 - 2019 Novel anti-cancer therapy with cyclic sulfide compounds regulating macrophage activation

Papers (13)：

Cheng Pan, Yukio Fujiwara, Hasita Horlad, Toyohisa Iriki, Daisuke Shiraishi, Yoshihiro Komohara. Cyclic sulfur compounds targeting macrophage polarization into M2/protumor phenotype and their anti-tumor effects. Cancer immunology, immunotherapy : CII. 2021
Yukio Fujiwara, Koji Ohnishi, Hasita Horlad, Yoichi Saito, Daisuke Shiraishi, Hiroto Takeya, Daiki Yoshii, Shinjiro Kaieda, Tomoaki Hoshino, Yoshihiro Komohara. CD163 deficiency facilitates lipopolysaccharide-induced inflammatory responses and endotoxin shock in mice. Clinical & Translational Immunology. 2020. 9. 9
Cheng Pan, Yukio Fujiwara, Hasita Horlad, Daisuke Shiraishi, Toyohisa Iriki, Jyunko Tsuboki, Tsuyoshi Ikeda, Yoshihiro Komohara. Flavonoid Compounds Contained in Epimedii Herba Inhibit Tumor Progression by Suppressing STAT3 Activation in the Tumor Microenvironment. Frontiers in pharmacology. 2020. 11. 262-262
菰原義弘, 白石大偉輔, 西東洋一, Hasita Horlad, 藤原章雄. M2-likeマーカーであるCD163はマクロファージの腫瘍促進性活性化に関与する. 日本がん免疫学会総会プログラム・抄録集. 2018. 22回. 154-154
Shiraishi D, Fujiwara Y, Horlad H, Saito Y, Iriki T, Tsuboki J, Cheng P, Nakagata N, Mizuta H, Bekki H, et al. CD163 Is Required for Protumoral Activation of Macrophages in Human and Murine Sarcoma. Cancer research. 2018. 78. 12. 3255-3266

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MISC (33)：

藤原章雄, 田中隆聖, 田中隆聖, 潘程, 白石大偉輔, 丸山徹, 菰原義弘. α1-acid glycoprotein contributes to cancer cell malignancy via tumor-associated macrophages. 日本癌学会学術総会抄録集(Web). 2023. 82nd
潘程, 藤原章雄, 矢野浩夢, 穴見俊樹, 白石大偉輔, 入來豊久, 菰原義弘. CRP is involved in tumor progression in clear cell renal cell carcinoma via macrophages. 日本癌学会学術総会抄録集(Web). 2023. 82nd
藤原章雄, 白石大偉輔, Horlad Hasita, 菰原義弘. 肉腫の腫瘍微小環境におけるマクロファージスカベンジャー受容体CD163の機能解析(Function of CD163, a macrophage scavenger receptor, in tumor microenvironment of sarcoma). 日本癌学会総会記事. 2018. 77回. 1383-1383
藤原章雄, 白石大偉輔, 潘程, 中川雄伸, 宮川育子, 菰原義弘. M2マクロファージマーカーの腫瘍進展における機能. 日本生化学会大会プログラム・講演要旨集. 2018. 91回. [2P-278]
菰原義弘, 白石大偉輔, 西東洋一, Hasita Horlad, 藤原章雄. M2-likeマーカーであるCD163はマクロファージの腫瘍促進性活性化に関与する. 日本がん免疫学会総会プログラム・抄録集. 2018. 22回. 154-154

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