Rchr
J-GLOBAL ID：201601010403627940   Update date: Sep. 03, 2024

Uemura Takeshi

Uemura Takeshi
Affiliation and department：
Josai University

About Josai University


Other affiliations (1)：
Research field  (5)： Food sciences ,  Forensic medicine ,  Cell biology ,  Molecular biology ,  Pharmaceuticals - health and biochemistry
Research keywords  (6)： Aging ,  Polyamine transport ,  Spermine oxidase ,  Brain stroke ,  Acrolein ,  Polyamine
Research theme for competitive and other funds  (12)：
  • 2022 - 2025 ポリアミンが誘導するリピート病の発症機構とその制御による病態抑制効果の解明
  • 2022 - 2025 Controlling the anti aging mechanism through modification of the protein translation pathway and Amine metabolizing pathway
  • 2022 - 2025 加齢によるスペルミン分解活性化機構解明と新規抗老化物質の創出
  • 2020 - 2021 尿中認知症リスクマーカー、3-HPMAの簡易測定法開発
  • 2017 - 2020 尿による認知症重症度が判断可能な検査キット開発
Show all
Papers (61)：
  • Teruyuki Kobayashi, Akihiko Sakamoto, Tamao Hisano, Keiko Kashiwagi, Kazuei Igarashi, Koichi Takao, Takeshi Uemura, Takemitsu Furuchi, Yoshiaki Sugita, Toshiyuki Moriya, et al. Caldomycin, a new guanidopolyamine produced by a novel agmatine homocoupling enzyme involved in homospermidine biosynthesis. Scientific reports. 2024. 14. 1. 7566-7566
  • Takeshi Uemura, Miki Matsunaga, Yuka Yokota, Koichi Takao, Takemitsu Furuchi. Inhibition of Polyamine Catabolism Reduces Cellular Senescence. International journal of molecular sciences. 2023. 24. 17
  • Hidenori Sanayama, Kiyonori Ito, Susumu Ookawara, Takeshi Uemura, Yoshio Sakiyama, Hitoshi Sugawara, Kaoru Tabei, Kazuei Igarashi, Kuniyasu Soda. Whole Blood Spermine/Spermidine Ratio as a New Indicator of Sarcopenia Status in Older Adults. Biomedicines. 2023. 11. 5
  • Teruyuki Kobayashi, Akihiko Sakamoto, Keiko Kashiwagi, Kazuei Igarashi, Koichi Takao, Takeshi Uemura, Toshiyuki Moriya, Tairo Oshima, Yusuke Terui. Putrescine Biosynthesis from Agmatine by Arginase (TtARG) in Thermus thermophilus. Journal of biochemistry. 2023
  • Hidenori Sanayama, Kiyonori Ito, Susumu Ookawara, Takeshi Uemura, Sojiro Imai, Satoshi Kiryu, Miho Iguchi, Yoshio Sakiyama, Hitoshi Sugawara, Yoshiyuki Morishita, et al. Positive Correlation between Relative Concentration of Spermine to Spermidine in Whole Blood and Skeletal Muscle Mass Index: A Possible Indicator of Sarcopenia and Prognosis of Hemodialysis Patients. Biomedicines. 2023. 11. 3
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MISC (21)：
  • 小林照幸, 坂本明彦, 柏木敬子, 五十嵐一衛, 高尾浩一, 植村武史, 森屋利幸, 大島泰郎, 照井祐介. Putrescine biosynthesis pathways in Thermus thermophilus. 日本ポリアミン学会年会プログラム及び抄録集. 2023. 13th
  • 小林照幸, 坂本明彦, 久野玉雄, 柏木敬子, 五十嵐一衛, 高尾浩一, 植村武史, 古地壯光, 杉田義昭, 森屋利幸, et al. Thermus thermophilusのホモスペルミジン生合成に関与する新規アグマチンホモカップリング酵素の同定. 日本ポリアミン学会年会プログラム及び抄録集. 2023. 14th
  • 小林照幸, 坂本明彦, 柏木敬子, 五十嵐一衛, 高尾浩一, 植村武史, 森屋利幸, 大島泰郎, 照井祐介. Thermus thermophilusにおけるアルギナーゼによるプトレシンの生合成. 日本生化学会大会(Web). 2023. 96th
  • 坂本明彦, 照井祐介, 植村武史, 植村武史, 五十嵐一衛, 五十嵐一衛, 柏木敬子. Polyamines stimulate the synthesis of circadian clock gene at the level of translation. 日本薬学会年会要旨集(Web). 2021. 141st
  • 植村武史, 植村武史, 中村瑞穂, 中村瑞穂, 坂本明彦, 照井祐介, 柏木敬子, 五十嵐一衛, 五十嵐一衛. Identification of potential preventors for brain stroke from foods. 日本薬学会年会要旨集(Web). 2021. 141st
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Patents (3)：
  • 脳血管障害および/または認知症の予防、治療および/または症状進展抑制剤
  • 細胞増殖の促進によりアルコール生産効率を向上させる方法
  • 細胞増殖を制御する遺伝子
Lectures and oral presentations  (8)：
  • Acrolein alters antigen recognition of immunoglobulin and increases matrix metalloproteinase 9 activity in primary Sjögren's syndrome patient
    (4th International Conference of Polyamines 2016)
  • Repression of polyamine metabolism reduces the acrolein cytotoxicity
    (BMB2015 2015)
  • 肝臓機能におけるポリアミン代謝の役割
    (農芸化学大会 2015)
  • Regulation of cellular polyamines by transport, protein sorting and metabolism
    (2013)
  • Caveolin and antizyme dependent regulation of protein sorting
    (Gordon Research Seminar on Polyamines 2011)
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Education (3)：
  • 2002 - 2005 Chiba Universoty Department of Pharmaceutical Sciences
  • 2000 - 2002 Chiba University
  • 1996 - 2000 Toho University
Work history (9)：
  • 2021/04 - 現在 Josai University
  • 2014/10 - 現在 Kyoto Prefectural University of Medicine Department of Forensic Medicine Lecturer
  • 2014/10 - 2021/03 Chiba University Department of Pharmaceutical Sciences Research Fellow
  • 2014/10 - 2021/03 AminePharma Research Institute Senior Scientist
  • 2014/02 - 2014/09 Kyoto Prefectural University of Medicine Department of Forensic Medicine Assistant Professor
Show all
Committee career (1)：
  • 2014/04 - 現在 日本ポリアミン学会 広報委員
Awards (3)：
  • 2018/11 - 一般財団法人 博慈会 博慈会 ダ・ビンチ賞
  • 2010/04 - Arizona Cancer Center Arizona Cancer Center SPORE in GI Cancer, Career Development Award
  • 2005/03 - Chiba University Best Ph D student award
Association Membership(s) (4)：
THE JAPANESE BIOCHEMICAL SOCIETY ,  THE PHARMACEUTICAL SOCIETY OF JAPAN ,  Japanese association of polyamine research ,  THE MOLECULAR BIOLOGY SOCIETY OF JAPAN
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