Rchr
J-GLOBAL ID:201601010695229908   Update date: Sep. 21, 2021

Makoto Taniguchi

タニグチ マコト | Makoto Taniguchi
Affiliation and department:
Job title: 講師
Homepage URL  (1): https://kaken.nii.ac.jp/d/r/30529433.ja.html
Research field  (2): Molecular biology ,  Cell biology
Research keywords  (11): Cell biology ,  Molecular Biology ,  plasma membrane ,  Viral infection ,  cancer ,  Lipid biochemistry ,  Sphongolipids ,  Ceramide ,  Lipid raft ,  Sphingomyelin synthase ,  Sphingomyelin
Research theme for competitive and other funds  (6):
  • 2021 - 2024 血小板膜におけるスフィンゴミエリンを介したリン脂質露呈制御機構の解明
  • 2020 - 2023 SMS阻害による癌微小環境免疫療法の分子機構解明
  • 2016 - 2019 スフィンゴミエリン/脂質ラフトを標的としたインプラント周囲炎の新たな予防法の開発
  • 2017 - 2019 スフィンゴミエリン合成酵素欠損による急性骨髄性白血病進行の抑制機構の解明
  • 2014 - 2017 Improvement effect of Alzheimer's disease brain by the omega -3 unsaturated fatty acid through the ion channel
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Papers (41):
  • Makoto Taniguchi, Toshiro Okazaki. Role of ceramide/sphingomyelin (SM) balance regulated through “SM cycle” in cancer. Cellular Signalling. 2021. 87. 110119-110119
  • Yoritaka Fujii, Makoto Taniguchi, Shingo Nagaya, Yoshibumi Ueda, Chieko Hashizume, Ken Watanabe, Hiroyuki Takeya, Takeo Kosaka, Toshiro Okazaki. A novel mechanism of thrombocytopenia by PS exposure through TMEM16F in sphingomyelin synthase 1 deficiency. Blood advances. 2021
  • Akari Shintani, Hiromi Sakata-Haga, Keiichi Moriguchi, Mitsuhiro Tomosugi, Daisuke Sakai, Tsuyoshi Tsukada, Makoto Taniguchi, Masahide Asano, Hiroki Shimada, Hiroki Otani, et al. MC5R Contributes to Sensitivity to UVB Waves and Barrier Function in Mouse Epidermis. JID Innovations. 2021. 100024-100024
  • Asuka Watanabe, Misa Togi, Terutsugu Koya, Makoto Taniguchi, Takuya Sakamoto, Kuniyoshi Iwabuchi, Tomohisa Kato Jr, Shigetaka Shimodaira. Identification of CD56dim subpopulation marked with high expression of GZMB/PRF1/PI-9 in CD56+ interferon-α-induced dendritic cells. Genes to cells : devoted to molecular & cellular mechanisms. 2021. 26. 5. 313-327
  • Shota Sakai, Asami Makino, Akihito Nishi, Takeshi Ichikawa, Tadashi Yamashita, Makoto Taniguchi, Yoshihiro Tokudome, Yoshio Hirabayashi, Masashi Akiyama, Debra Crumrine, et al. Pathogenic and Compensatory Mechanisms in Epidermis of Sphingomyelin Synthase 2-Deficient Mice. Skin pharmacology and physiology. 2021. 1-7
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MISC (25):
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Patents (1):
  • 造血器腫瘍治療剤、およびスクリーニング方法
Lectures and oral presentations  (3):
  • Ceramide/sphingomyelin balance regulated by sphingomyelin synthase in murine disease models.
    (The 141st Annual Meeting of the Pharmaceutical Society of Japan 2021)
  • スフィンゴミエリン合成酵素欠損マウス -動物病態モデルの利用と応用-
    (ConBio 2017 2017)
  • 日本脳炎ウイルス感染におけるスフィンゴミエリンの役割
    (第33回 日本生化学会北陸支部会 2015)
Education (1):
  • 2003 - 2006 Tottori University Division of Molecular Biology
Work history (4):
  • 2014/04 - 現在 Kanazawa Medical University Medical Research Institute Lecturer
  • 2012/06 - 2014/03 Kanazawa Medical University Medical Research Institute Assistant Professor
  • 2010/09 - 2012/05 Tottori University Faculty of Medicine PostDoc
  • 2006/04 - 2010/08 Tottori University Faculty of Medicine PostDoc
Committee career (1):
  • 2019/08 - 現在 スフィンゴテラピィ研究会 組織委員(事務局長)
Awards (1):
  • 2017/01 - 金沢医科大学 優良教員賞(研究活動部門)
Association Membership(s) (2):
JAPANESE SOCIETY OF RADIATION SAFETY MANAGEMENT ,  THE JAPANESE BIOCHEMICAL SOCIETY
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