2014 - 2017 Improvement effect of Alzheimer's disease brain by the omega -3 unsaturated fatty acid through the ion channel
2013 - 2016 日本脳炎ウイルス感染におけるスフィンゴミエリン/脂質ラフトの役割
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Papers (44):
Mao Kondo, Koki Kimura, Jingjing Kobayashi-Sun, Shiori Yamamori, Makoto Taniguchi, David Traver, Isao Kobayashi. The sinusoidal hematopoietic niche is formed by Jam1a via Notch signaling in the zebrafish kidney. iScience. 2023. 26. 4. 106508
Makoto Taniguchi, Shingo Nagaya, Kohei Yuyama, Ai Kotani, Yasuyuki Igarashi, Toshiro Okazaki. Ceramide Metabolism Regulated by Sphingomyelin Synthase 2 Is Associated with Acquisition of Chemoresistance via Exosomes in Human Leukemia Cells. International Journal of Molecular Sciences. 2022. 23. 18. 10648
Jun Fujita, Makoto Taniguchi, Chieko Hashizume, Yoshibumi Ueda, Shota Sakai, Tadakazu Kondo, Mayumi Hashimoto-Nishimura, Kentaro Hanada, Takeo Kosaka, Toshiro Okazaki. Nuclear Ceramide Is Associated with Ataxia Telangiectasia Mutated Activation in the Neocarzinostatin-Induced Apoptosis of Lymphoblastoid Cells. Molecular pharmacology. 2022. 101. 5. 322-333
Makoto Taniguchi, Toshiro Okazaki. Role of ceramide/sphingomyelin (SM) balance regulated through “SM cycle” in cancer. Cellular Signalling. 2021. 87. 110119
Yoritaka Fujii, Makoto Taniguchi, Shingo Nagaya, Yoshibumi Ueda, Chieko Hashizume, Ken Watanabe, Hiroyuki Takeya, Takeo Kosaka, Toshiro Okazaki. A novel mechanism of thrombocytopenia by PS exposure through TMEM16F in sphingomyelin synthase 1 deficiency. Blood advances. 2021. 5. 20. 4265-4277
Ceramide/sphingomyelin balance regulated by sphingomyelin synthase in murine disease models.
(The 141st Annual Meeting of the Pharmaceutical Society of Japan 2021)
Deficiency of sphingomyelin synthase 2 prolongs survival by inhibition of lymphoma infiltration through ICAM-1 reduction
(第14回スフィンゴテラピィ研究会 2020)
Deficiency of sphingomyelin synthase 2 prolongs survival by inhibition of lymphoma infiltration through ICAM-1 reduction
(第55回金沢医科大学 医学会学術集会 2019)
Deficiency of SMS2 suppresses the infiltration of EL4 T lymphoma cells through ICAM-1 reduction
(第13回スフィンゴテラピィ研究会 2018)