Research field (5):
Pathobiochemistry
, Molecular biology
, Developmental biology
, Tumor biology
, Orthopedics
Research keywords (4):
Development
, 骨軟部腫瘍
, 転移メカニズム
, シグナル伝達
Research theme for competitive and other funds (7):
2021 - 2024 骨軟部腫瘍の肺転移における治療抵抗性メカニズムの解析
2018 - 2022 Investigating the new strategy to suppress lung metastasis of sarcomas
2015 - 2018 Understanding molecular mechanism underlying innate immune system escape for metastasis in sarcoma
2012 - 2015 Investigation of collective molecular mechanisms in stemness and metastasis in sarcoma
2009 - 2009 造血幹細胞・白血病関連因子のシステム解析による新規な生物作用の解明
2005 - 2009 System analysis of stability and plasticity of signal transduction
2003 - 2004 Systems analysis of molecular networks based on biochemical computational simulations
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Papers (30):
Satoru Sasagawa, Jun Kumai, Toru Wakamatsu, Yoshihiro Yui. Improvement of histone deacetylase inhibitor efficacy by SN38 through TWIST1 suppression in synovial sarcoma. Cancer innovation. 2024. 3. 2. e113
Rie Suzuki, Toru Wakamatsu, Keiichi Yoshida, Yukiko Matsuoka, Haruna Takami, Sho Nakai, Hironari Tamiya, Shigeki Kakunaga, Toshinari Yagi, Ken-ichi Yoshida, et al. Genetic characterization of a novel organoid from human malignant giant-cell tumor. Journal of Bone Oncology. 2023. 41. 100486-100486
Yoshihiro Yui, Jun Kumai, Kenta Watanabe, Toru Wakamatsu, Satoru Sasagawa. Lung fibrosis is a novel therapeutic target to suppress lung metastasis of osteosarcoma. International Journal of Cancer. 2022
Toru Wakamatsu, Hisataka Ogawa, Keiichi Yoshida, Yukiko Matsuoka, Kazuko Shizuma, Yoshinori Imura, Hironari Tamiya, Sho Nakai, Toshinari Yagi, Shigenori Nagata, et al. Establishment of Organoids From Human Epithelioid Sarcoma With the Air-Liquid Interface Organoid Cultures. Frontiers in oncology. 2022. 12. 893592-893592
Jun Kumai, Satoru Sasagawa, Masanobu Horie, Yoshihiro Yui. A Novel Method for Polyacrylamide Gel Preparation Using N-hydroxysuccinimide-acrylamide Ester to Study Cell-Extracellular Matrix Mechanical Interactions. Frontiers in Materials. 2021. 8