2020 - 2024 Development of novel therapies for idiopathic pulmonary pneumonia with a human primary lung epithelial cell model
2020 - 2023 細胞質移植マイクロ流体デバイス開発による高収率・細胞機能改変手法の創製
2020 - 2023 Reconstitution of Physiologically Relevant 3D Blood-Brain Barrier Model for the Elucidation of its Selective Transport Mechanism
2017 - 2020 Development of functional bronchial ciliated cell sheet from human iPS cells
2017 - 2020 微小培養環境制御に基づく幹細胞組織のメカノバイオロジー研究
2018 - 2020 バイオプロセッシングに関する研究
2019 - 2019 The 4th Africa International Biotechnology and Biomedical Conference & Workshops (AIBBC 2019)
2015 - 2019 Cell-fusion-based single-cell surgery and its application to epigenetic studies
2016 - 2018 Development of a microdevice for the study of the interaction between endothelial cells and neuronal cells
2017 - 2017 The 3rd Africa International Biotechnology and Biomedical Conference & Workshops (AIBBC 2017)
2013 - 2015 Toward Developing a Microdevice for Elucidating the Mechanism of Blood-Nerve Interactions
2011 - 2015 Modification of cellular function based on cell fusion in microdevices
2014 - 2014 The 1rd Africa International Biotechnology and Biomedical Conference & Workshops (AIBBC 2014)
2012 - 2014 局所的細胞融合技術を用いたミトコンドリア移植とその生物学的応用に関する研究
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Papers (36)：
Songshi Li, Daisuke Kawashima, Kennedy Omondi Okeyo, Takeshi Murata, Masahiro Takei. Assessment of anisotropic transmembrane transport coefficient vector of cell-spheroid under inhomogeneous ion concentration distribution fields by electrical impedance tomography. Measurement Science and Technology. 2023. 34. 3. 035701-035701
Kennedy Omondi Okeyo, Ryuta Hiyaji, Hidehiro Oana. A single-cell surgery microfluidic device for transplanting tumor cytoplasm into dendritic cells without nuclei mixing. Biotechnology journal. 2023. 18. 1. e2200135
S.Li, D.Kawashima, M.Sugawara, H.Obara, K.O.Okeyo, M.Takei. Study of transmembrane ion transport under tonicity imbalance using a combination of low frequency-electrical impedance spectroscopy (LF-EIS) and improved ion transport model. Biomedical Physics & Engineering Express. 2022. 8. 3. 035024-035024
Yuta Ando, Kennedy Omondi Okeyo, Taiji Adachi. Pluripotency state of mouse ES cells determines their contribution to self-organized layer formation by mesh closure on microstructured adhesion-limiting substrates. Biochemical and Biophysical Research Communications. 2022. 590. 97-102
Kennedy O. Okeyo, Yoshikiyo Kibe, Taiji Adachi. Controlling macroscale cell alignment in self-organized cell sheets by tuning the microstructure of adhesion-limiting micromesh scaffolds. Materials Today Advances. 2021. 12. #100194
K. O. Okeyo, O. Kurosawa, H. Oana, M. Washizu. MODULATING THE CELL ADHESION MICROENVIRONMENT TO MECHANICALLY DRIVE TROPHECTODERM-LIKE ORGANOID FORMATION FROM HUMAN iPS CELLS. 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019. 2019. 290-291
Kennedy O. Okeyo, Kai Yamada, Osamu Kurosawa, Hidehiro Oana, Masao Washizu. Reconstituting a Bilayer Cellular System Using an Artificial Matrigel Basement Membrane Achieved by the Micromesh Technique. 2018 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2018. 2018
Kennedy O. Okeyo, Kai Yamada, Osamu Kurosawa, Hidehiro Oana, Masao Washizu. RECONSTITUTION OF AN EPITHELIAL-ENDOTHELIAL BILAYER BY THE MICROMESH CULTURE TECHNIQUE EMPLOYING AN ARTIFICIAL MATRIGEL BASEMENT MEMBRANE. 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2018). 2018. 3. 1617-1619
Biochip Technologies- Principles and Applications-
2015 ISBN:9784781310794
Innovative Approaches to Cell Biomechanics: From Cell Migration to On-Chip Manipulation
Springer 2015
Lectures and oral presentations (53)：
剛性異方性基板を用いた細胞シートの配向性誘導
(第32回バイオフロンティア講演会)
Cell alignment in response to substrate stiffness anisotropy investigated using membrane-on-mesh substrates
(The 11th Asian-Pacific Conference on Biomechanics)
Macroscale level control of collective cell alignment by tuning stiffness anisotropy
(The 11th Asian-Pacific Conference on Biomechanics (AP Biomech 2021) 2021)
Discerning the differentiation potential of human pluripotent stem cells by modulating the adhesion microenvironment
(The 11th International Conference on Post-Genomic Technologies 2021)
Contribution of tissue morphology to localized changes in pluripotency state assessed using self-organized mouse embryonic stem cell layers on island mesh substrates.
(The 33rd Bioengineering Conference Annual Meeting of Bioengineering Division, The Japan Society of Mechanical Engineers 2021)
2018/04 - 現在 Japan Society of Mechanical Engineers (JSME) International Union
2014/04 - 現在 Africa International Biotechnology and Biomedical Conference (AIBBC) Organizing Committee
2020/06 - 2020/11 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences Social Committee
2018 - 2018 日本機械学会 日本機械学会バイオエンジニアリング講演会実行委員
2017/02 - 2017/12 The 30th Bioengineering Conference Annual Meeting of Bioengineering Division/ The Japan Society of Mechanical Engineers Executive committee
2013/01 - 若手細胞研究会 イノバイオ研究会定例会企画員
2012/09 - 若手細胞研究会 イノバイオ研究会定例会企画員
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Awards (8)：
2019/11 - The 10th Asian-Pacific Conference on Biomechanics (AP Biomech 2019) Best Oral Presentation Award Self-organization and Differentiation of Stem Cells Triggered Mechanically by Adhesion Restriction using Suspended Microstructured Mesh Substrates
2018/12 - Micro-NanoMechatronics and Human Science IEEE/MHS Best Paper Award
2018/10 - Royal Society of Chemistry Lab on a Chip Poster Prize Direct acquisition of individual target chromosomes isolated from single mammalian cells in a microfluidic channel for single cell/chromosome
2016/04 - Microtechnologies in Medicine and Biology (MMB2016) Best Poster Award,
2015/11 - IEEE/, NAGOYA 2015 International Symposium on Micro-NanoMechatronics and Human Science (MHS 2015) BEST PAPER AWARD
2014/04 - 一般社団法人日本機械学会 日本機械学会奨励賞(研究)
2010/03 - Journal of Biomechanical Science and Engineering (JBSE) Paper of the Year
2009/01 - 帝人株式会社 「帝人21世紀フォーラム(2009)」奨励賞
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Association Membership(s) (5)：
日本機械学会
, CHEMINAS
, International Conference on Miniaturized Systems for Chemistry and Life Sciences (Social Committee Member, MicroTAS 2021, online)
, Tissue Engineering and Regenerative Medicine International Society (TERMIS)
, Africa International Biotechnology and Biomedical Conference, AIBBC (Founding member, Chief organizer)
