Rchr
J-GLOBAL ID:201601012908924837   Update date: Feb. 08, 2024

Tsukita Sachiko

ツキタ サチコ | Tsukita Sachiko
Homepage URL  (1): http://www.fbs.osaka-u.ac.jp/labs/tsukita/
Research field  (1): Cell biology
Research theme for competitive and other funds  (54):
  • 2019 - 2024 Novel approach focusing on the tight junction-based paracellular barrier combined with the apical barrier toward understanding and manipulating epithelial barriers
  • 2018 - 2020 上皮バリアの構築と機能を制御するタイトジャンクション・アピカル複合体の解析
  • 2017 - 2019 The establishment of intercellular co-ordination of ciliary movement by using human iPS cell-derived airway epithelial cells
  • 2012 - 2017 The role of apical cytoskeletons in transition between centrosomes and ciliary basal bodies.
  • 2012 - 2017 Cilium-centrosome system regulating biosignal flows
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Papers (207):
  • Gen Shiratsuchi, Satoshi Konishi, Tomoki Yano, Yuichi Yanagihashi, Shogo Nakayama, Tatsuya Katsuno, Hiroka Kashihara, Hiroo Tanaka, Kazuto Tsukita, Koya Suzuki, et al. Dual-color live imaging unveils stepwise organization of multiple basal body arrays by cytoskeletons. EMBO Reports. 2024
  • Koya Suzuki, Kosuke Yamaga, Reitaro Tokumasu, Tatsuya Katsuno, Hiroo Tanaka, Shuhei Chiba, Takeshi Yagi, Ichiro Katayama, Atsushi Tamura, Hiroyuki Murota, et al. Double mutation of claudin-1 and claudin-3 causes alopecia in infant mice. Annals of the New York Academy of Sciences. 2023. 1523. 1. 51-61
  • Kazuto Tsukita, Manabu Kitamata, Hiroka Kashihara, Tomoki Yano, Ikuko Fujiwara, Timothy F Day, Tatsuya Katsuno, Jaewon Kim, Fumiko Takenaga, Hiroo Tanaka, et al. Phase separation of an actin nucleator by junctional microtubules regulates epithelial function. Science advances. 2023. 9. 7. eadf6358
  • Fabian Eisenstein, Haruaki Yanagisawa, Hiroka Kashihara, Masahide Kikkawa, Sachiko Tsukita, Radostin Danev. Parallel cryo electron tomography on in situ lamellae. Nature methods. 2022. 20. 1. 131-138
  • Shintaro Sugiyama, Tsutomu Sasaki, Hiroo Tanaka, Haomin Yan, Takeshi Ikegami, Hideaki Kanki, Kumiko Nishiyama, Goichi Beck, Yasufumi Gon, Shuhei Okazaki, et al. The tight junction protein occludin modulates blood-brain barrier integrity and neurological function after ischemic stroke in mice. 2022
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MISC (110):
  • 中村駿, 中村駿, 入江克雅, 入江克雅, 田中啓雄, 田村淳, 月田早智子, 藤吉好則, 藤吉好則. Claudin-3の結晶構造が明らかにするタイトジャンクション形態の決定要素. 日本細胞生物学会大会(Web). 2019. 71st
  • Electron microscopic study of TJ-apical complex in epithelial cell sheets. 2018. 47. 20-24
  • Down-regulation of Claudin-1 demonstrates the pathology of atopic dermatitis. 2017. 67. 6. 599-605
  • 岡野 達郎, 竹内 そら, 相馬 良直, 鈴木 浩也, 月田 早智子, 石津 明洋, 鈴木 和男, 川上 民裕. 血管炎・その他の免疫疾患 皮膚限局の血管炎が重症化した際の抗モエシン抗体の推移について. アレルギー. 2017. 66. 4-5. 621-621
  • 鈴木浩也, 田中啓雄, 田村淳, 月田早智子. タイトジャンクションによる上皮細胞間バリア機能:クローディンを軸とした生体システム構築. 実験医学. 2017
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Education (3):
  • 1978 - 1983 The University of Tokyo
  • 1976 - 1978 The University of Tokyo
  • 1972 - 1976 The University of Tokyo Faculty of Pharmaceutical Sciences
Professional career (1):
  • 医学博士 (東京大学)
Work history (9):
  • 2022/04 - 現在 Teikyo University Advanced Comprehensive Research Organization Professor
  • 2007/04 - 2022/03 Osaka University
  • 2003/04 - 2007/03 Kyoto University
  • 1994/04 - 2007/03 Kyoto University Faculty of Medicine
  • 1990/04 - 1994/03 岡崎国立共同研究機構生理学研究所 生体情報系 助手
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Awards (5):
  • 2015/03 - 東レ科学技術財団 東レ科学賞
  • 2014/07 - 大阪大学 総長顕彰(研究部門)
  • 2013/08 - 大阪大学 総長顕彰(研究部門)
  • 2012/04 - 文部科学省 文部科学大臣表彰科学技術賞(研究部門)
  • 1988/05 - 日本電子顕微鏡学会 瀬藤賞
Association Membership(s) (7):
JAPAN SOCIETY FOR CELL BIOLOGY ,  THE MOLECULAR BIOLOGY SOCIETY OF JAPAN ,  THE JAPANESE BIOCHEMICAL SOCIETY ,  THE JAPANESE ASSOCIATION OF ANATOMISTS ,  THE JAPANESE CANCER ASSOCIATION ,  THE JAPANESE SOCIETY OF MICROSCOPY ,  アメリカ細胞生物学会
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