AMIT RAI

Rai Amit | AMIT RAI

Research field (4)： Plants: molecular biology and physiology , Environmental and pharmaceutical development resources , Molecular biochemistry , Functional biochemistry

Research keywords (5)： Monoterpenoids Indole Alkaloids , Interative Omics Approach , Traditional Japanese Medicine , Metabolic engineering , Plant functional genomics

Research theme for competitive and other funds (6)：

2022 - 2027 Prediction and engineering of complex system biosynthetic pathways based on genome-metabolomics
2019 - 2024 Genomic origin of chemodiversity in medicinal plants
2019 - 2023 Integrated genomic science of domestically produced important medicinal resource plants
2019 - 2022 Systems biology approach to unravel biosynthesis and evolution of camptothecin, a potent anti-cancer natural product
2015 - 2019 Integrated genomics on important medicinal plants in Leguminosae

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Papers (32)：

Dongjin Choi, Megha Rai, Amit Rai, Chaerim Shin, Mami Yamazaki, Yoonsoo Hahn. High-throughput RNA sequencing analysis of Mallotus japonicus revealed novel polerovirus and amalgavirus. Acta virologica. 2023. 67. 1. 13-23
Tetsuya Mori, Amit Rai, Hiroshi Tsugawa, Yutaka Yamada, Kazuki Saito. A liquid chromatography-mass spectrometry-based metabolomics strategy to explore plant metabolic diversity. Methods in enzymology. 2023. 680. 247-273
Amit Rai, Hideki Hirakawa, Megha Rai, Yohei Shimizu, Kenta Shirasawa, Shinji Kikuchi, Hikaru Seki, Mami Yamazaki, Atsushi Toyoda, Sachiko Isobe, et al. Chromosome-scale genome assembly of Glycyrrhiza uralensis revealed metabolic gene cluster centred specialized metabolites biosynthesis. DNA research : an international journal for rapid publication of reports on genes and genomes. 2022. 29. 6
Amit Rai, Hideki Hirakawa, Ryo Nakabayashi, Shinji Kikuchi, Koki Hayashi, Megha Rai, Hiroshi Tsugawa, Taiki Nakaya, Tetsuya Mori, Hideki Nagasaki, et al. Chromosome-level genome assembly of Ophiorrhiza pumila reveals the evolution of camptothecin biosynthesis. Nature Communications. 2021. 12. 1. 405-405
Hiroshi Tsugawa, Amit Rai, Kazuki Saito, Ryo Nakabayashi. Metabolomics and complementary techniques to investigate the plant phytochemical cosmos. Natural product reports. 2021. 38. 10. 1729-1759

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MISC (44)：

鵜崎真妃, 鵜崎真妃, 山本浩太郎, 山本浩太郎, RAI Amit, 村上明男, 大西美輪, 七條千津子, 石崎公庸, 深城英弘, et al. Initiation process of Monoterpneoid indole alkaloid biosynthesis during seed germination in Catharanthus roseus. 日本植物生理学会年会(Web). 2022. 63rd
二反田望実, RAI Amit, 齊藤和季, 山崎真巳. Characterization of Transporter Genes Located within Biosynthetic Gene Cluster for Camptothecin Production in Ophiorrhiza pumila. 日本植物生理学会年会(Web). 2022. 63rd
RAI Amit, HIRAKAWA Hideki, NAKABAYASHI Ryo, KIKUCHI Shinji, HAYASHI Koki, RAI Megha, TSUGAWA Hiroshi, MORI Tetsuya, YAMAZAKI Mami, SAITO Kazuki. Multi-omics driven approach explores the evolution of specialized metabolites in plants. 質量分析総合討論会講演要旨集. 2021. 69th
山崎真巳, RAI Amit, 北村智, 齊藤和季. Integrative omics for understanding of camptothecin biosynthesis. 日本薬学会年会要旨集(Web). 2021. 141st
二反田望実, RAI Amit, 斉藤和季, 山崎真巳. チャボイナモリのカンプトテシン生合成遺伝子クラスターに存在するトランスポーター遺伝子のノックアウト毛状根の作製. 日本薬学会関東支部大会講演要旨集. 2021. 65th (CD-ROM)

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Lectures and oral presentations (11)：

De novo transcriptome studies as a tool for unveiling the chemical diversity and processes involved in their biosynthesis in the Medicinal plants.
(The 3rd Plant Genomics Congress Asia, Kuala Lumpur, Malaysia 2016 2016)
Comparative transcriptomics across selected plants from Panax genus revealed cyp450s and GTs coding genes with potential role in triterpene saponin biosynthesis.
(Japan Society Plant Physiology conference, Morioka, Iwate, Japan 2016 2016)
QuoA expression in Arabidopsis leads to phenolamide channeling to lignins and coordinated effects at key branch points
(Merlion Metabolomics, Singapore 2014 2014)
Integrative multi-omics analysis on Microcystis aeruginosa at varying environmental conditions revealed key processes contributing to toxin production.
(Agilent Technology Integrated Biology Workshop. Monash University, Kuala Lumpur 2014)
Isolation of a rice mutant with altered shoot architecture and use of metabolomics for gene function discovery
(International Association of Plant Biotechnology Congress. Melbourne, Australia 2014)

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Education (2)：

2008 - 2013 National University of Singapore Department of Biological Sciences Doctor of Philosophy
2004 - 2008 Birla Institute of Technology Department of Biotechnology Bachelors of Engineering

Professional career (1)：

Ph.D. (National University of Singapore)

Work history (5)：

2020 - 現在 Chiba University Plant Molecular Biology Center Guest Assistant Professor
2015/01 - 現在 Chiba University Graduate School of Pharmaceutical Sciences Specially Appointed Assistant Professor
2013/07 - 2014/12 National University of Singapore Metabolite Biology Laboratory Post-Doctoral Fellow
2013/01 - 2013/06 National University of Singapore Metabolite Biology Laboratory Research Assistant
2012/08 - 2012/12 National University of Singapore Plant Morphogenesis Lab Research Assistant

Committee career (4)：

2015 - 現在 Plant Metabolism and Chemodiversity Review Editor
2012 - 2013 NUS-Environmental Research Institute Committee for safety management
2011 - 2012 DBS graduate student committee
2007 - 2008 Ecological and Environmental Society General Secretary

Awards (6)：

2022/03 - RIKEN, Japan Letter of appreciation Letter of appreciation for special recognition for outstanding research achievements and contribution to increased public recognition of RIKEN and its scientific activities
2021/09 - 72nd Annual Meeting of the SCR The Best Presentation Award
2014/11 - Merlion Metabolites Workshop Singapore 2014, National University of Singapore, Singapore Young Researcher Award
2010/11 - Faculty of Science, National University of Singapore, Singapore Best Teaching Assistant
2009/03 - Birla Institute of Technology Gold Medal Best Undergrad Student

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Association Membership(s) (4)：

Japan Society Plant Physiology , The Society of Experimental Botany , The Singapore Society of Mass Spectrometry , Metabolomics Society

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