2015 - 2018 Novel functions and relevance to the diseases of intracellular phospholipase A1
2015 - 2017 スフィンゴミエリン合成酵素のオリゴマー形成領域の同定と 機能解析
2012 - 2015 Research for the novel metabolic routes of endogenous marijuana-like substance, lysophosphatidylinosiol.
2013 - 2015 スフィンゴミエリン合成酵素を標的とした抗HIV剤の開発
2010 - 2012 内因性カンナビノイドを産生する新規ホスファチジルイノシトール代謝経路の解明
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Papers (40):
Yasuhiro Hayashi, Takehiro Suzuki, Naoto Horioka, Naoshi Dohmae, Takashi Tanikawa. Phospholipid Scramblase 1 Localizes Proximal to Sphingomyelin Synthase Isoforms but Is Not Involved in Sphingomyelin Synthesis. Biological and Pharmaceutical Bulletin. 2024. 47. 6. 1136-1143
Yasuhiro Hayashi, Nanami Higa, Tetsuro Yoshida, Trianda Ayuning Tyas, Kanami Mori-Yasumoto, Mina Yasumoto-Hirose, Hideki Tani, Junichi Tanaka, Takahiro Jomori. Onnamide A suppresses the severe acute respiratory syndrome-coronavirus 2 infection without inhibiting 3-chymotrypsin-like cysteine protease. The Journal of Biochemistry. 2024. 176. 3. 197-203
Yasuhiro Hayashi, Sei Arizono, Takashi Tanikawa. Comparison of anti-SARS-CoV-2 activity of commercial dairy products. Journal of Dairy Research. 2024
Yasuhiro Hayashi, Xuhao Huang, Takashi Tanikawa, Kazunari Tanigawa, Mizuki Yamamoto, Jin Gohda, Jun-Ichiro Inoue, Koichi Fukase, Kazuya Kabayama. Reactive oxygen species are associated with the inhibitory effect of N-(4-hydroxyphenyl)-retinamide on the entry of the severe acute respiratory syndrome-coronavirus 2. Journal of biochemistry. 2023
TAKASHI TANIKAWA, MASASHI KITAMURA, YASUHIRO HAYASHI, NATSUMI TOMIDA, AKEMI UWAYA, FUMIYUKI ISAMI, TAKAMI YOKOGAWA, YUTAKA INOUE. Anti-inflammatory Effect of a Combination of Cannabidiol andMorinda citrifoliaExtract on Lipopolysaccharide-stimulated RAW264 Macrophages. In Vivo. 2023. 37. 2. 591-595
Sphingomyelin synthase 1 forms a complex with glucosylceramide synthase that is involved in the regulation of selective ceramide usage
(Gordon Research Conference, Galveston, USA (招待講演) 2018)
Carboxyl-terminal-mediated homodimerizations of sphingomyelin synthases are responsible for efficient ER export
(理化学研究所 脳科学総合研究センター研究会 (招待講演) 2016)
Education (3):
2004 - 2007 九州大学大学院 生物資源環境科学府 博士後期課程
2002 - 2004 九州大学大学院 生物資源環境科学府 修士課程
1998 - 2002 Kyushu University School of Agriculture
Professional career (1):
博士(農学) (九州大学)
Work history (5):
2022/01 - 現在 Miyazaki University Faculty of Agriculture
2020/04 - 2021/12 Teikyo University Faculty of Pharma-Science
2010/04 - 2020/03 Teikyo University Faculty of Pharma-Science
2008/04 - 2010/03 アメリカ国立衛生研究所 Visiting Fellow
2007/04 - 2008/03 九州大学大学院 CREST 研究員
Awards (2):
2007/09 - Poster Award, 48th International Conference on the Bioscience of Lipids "A novel catabolic pathway of glycosphingolipids mediated with a Klotho-related protein"
2006/08 - ポスター賞、 第26回 日本糖質学会年会 "Klotho related proteinはグルコセレブロシダーゼ活性を有する"
Association Membership(s) (3):
日本ウィルス学会
, THE JAPANESE CONFERENCE ON THE BIOCHEMISTRY OF LIPIDS
, THE JAPANESE BIOCHEMICAL SOCIETY