Rchr
J-GLOBAL ID:201601014252541181   Update date: Feb. 01, 2024

TOMOAKI KOGA

コガ トモアキ | TOMOAKI KOGA
Affiliation and department:
Other affiliations (1):
Homepage URL  (1): http://www.imeg.kumamoto-u.ac.jp/bunya_top/medical_cell_biology/
Research field  (3): Pharmaceuticals - health and biochemistry ,  Immunology ,  Medical biochemistry
Research keywords  (15): Inflammation memory ,  epigenetics ,  lipid mediator ,  BLT2 ,  epithelial cells ,  T cell ,  macrophage ,  Dendritic cells ,  BLT1 ,  LTB4 ,  Lipid Immunology ,  GPCR ,  Lipid ,  Immunology ,  Inflammation
Research theme for competitive and other funds  (12):
  • 2023 - 2028 炎症メモリー細胞可視化マウスを用いた慢性炎症疾患の新規治療標的の探索
  • 2023 - 2027 生体防御システムにおける骨格筋の新たな役割
  • 2023 - 2026 シン・マルチエピゲノム解析を基盤とした免疫細胞の多階層オミクス解析
  • 2020 - 2024 Analysis of epigenome and metabolic phenotypes in Thai liver fluke-associated cholangiocarcinoma
  • 2020 - 2023 Elucidation of Epigenome network for regulating inflammation memory
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Papers (81):
  • Ryo Ikeda, Daisuke Noshiro, Hideaki Morishita, Shuhei Takada, Shun Kageyama, Yuko Fujioka, Tomoko Funakoshi, Satoko Komatsu-Hirota, Ritsuko Arai, Elena Ryzhii, et al. Phosphorylation of phase-separated p62 bodies by ULK1 activates a redox-independent stress response. The EMBO journal. 2023. e113349
  • Ubonrat Thamrongwaranggoon, Kanji Kuribayashi, Hirotaka Araki, Yuko Hino, Tomoaki Koga, Wunchana Seubwai, Sopit Wongkham, Mitsuyoshi Nakao, Shinjiro Hino. Lactic acidosis induces metabolic and phenotypic reprogramming in cholangiocarcinoma cells via the upregulation of THBS1. Cancer Science. 2022
  • Ubonrat Thamrongwaranggoon, Marutpong Detarya, Wunchana Seubwai, Charupong Saengboomee, Shinjiro Hino, Tomoaki Koga, Mitsuyoshi Nakao, Sopit Wongkham. Lactic acidosis promotes aggressive features of cholangiocarcinoma cells via upregulating ALDH1A3 expression through EGFR axis. Life sciences. 2022. 302. 120648-120648
  • Tomoka Igata, Hiroshi Tanaka, Kan Etoh, Seonghyeon Hong, Naoki Tani, Tomoaki Koga, Mitsuyoshi Nakao. Loss of the transcription repressor ZHX3 induces senescence-associated gene expression and mitochondrial-nucleolar activation. PloS one. 2022. 17. 1. e0262488
  • 古賀 友紹, 横溝 岳彦, 中尾 光善. 新しい脂質メディエーターの潮流〜山本尚三先生を偲ぶ〜 LTB4/BLT1経路による新規樹状細胞サブセットの機能制御. 脂質生化学研究. 2021. 63. 7-7
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MISC (50):
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Books (3):
  • Clinical Immunology & Allergy
    2018
  • Bioactive Lipid Mediators
    Springer Japan 2015
  • 疾患モデルの作製と利用ー脂質代謝異常と関連疾患ー
    LIC出版 2015
Lectures and oral presentations  (4):
  • ロイコトリエンB4とその受容体BLT1による樹状細胞の機能制御
    (第43回日本分子生物学会フォーラム「脂質多様性を基軸とした炎症・免疫制御」 2020)
  • Regulation of monocytic cell subsets by lipid mediator and epigenome
    (2019)
  • 生理活性脂質ロイコトリエンB4受容体BLT1による生体防御応答
    (第7回 オルソオルガノジェネシス検討会 2017)
  • BLT1 as a marker for novel dendritic subset
    (2014)
Professional career (1):
  • 博士(薬学) (熊本大学)
Committee career (1):
  • 2023/04 - 現在 Frontiers in Immunology Associate Editor
Association Membership(s) (7):
日本薬学会 ,  日本脂質免疫学研究会 ,  日本免疫学会 ,  日本脂質生化学会 ,  日本エピジェネティクス研究会 ,  日本生化学会 ,  日本分子生物学会
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