Rchr
J-GLOBAL ID:201601014252541181   Update date: Oct. 23, 2021

TOMOAKI KOGA

コガ トモアキ | TOMOAKI KOGA
Affiliation and department:
Other affiliations (1):
Homepage URL  (1): http://www.imeg.kumamoto-u.ac.jp/bunya_top/medical_cell_biology/
Research field  (3): Pharmaceuticals - health and biochemistry ,  Immunology ,  Medical biochemistry
Research keywords  (15): Inflammation memory ,  epigenetics ,  lipid mediator ,  BLT2 ,  epithelial cells ,  T cell ,  macrophage ,  Dendritic cells ,  BLT1 ,  LTB4 ,  Lipid Immunology ,  GPCR ,  Lipid ,  Immunology ,  Inflammation
Research theme for competitive and other funds  (9):
  • 2020 - 2024 Analysis of epigenome and metabolic phenotypes in Thai liver fluke-associated cholangiocarcinoma
  • 2020 - 2023 炎症メモリーを制御するエピゲノムネットワークの解明
  • 2017 - 2020 免疫細胞におけるLTA4水解酵素の生化学的機能解析
  • 2016 - 2019 Regulation of leukotriene B4 receptor2(BLT2) accelerates corneal wound by NSAIDs
  • 2015 - 2018 The roles of receptors for lipid mediators in inflammation, immunity and barrier function
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Papers (75):
  • Unchalee Thonsri, Sopit Wongkham, Chaisiri Wongkham, Shinjiro Hino, Mitsuyoshi Nakao, Sittiruk Roytrakul, Tomoaki Koga, Wunchana Seubwai. High glucose-ROS condition enhances progression in cholangiocarcinoma via upregulation of MAN2A2 and CHD8. Cancer science. 2020
  • Tomoaki Koga, Fumiyuki Sasaki, Kazuko Saeki, Soken Tsuchiya, Toshiaki Okuno, Mai Ohba, Takako Ichiki, Satoshi Iwamoto, Hirotsugu Uzawa, Keiko Kitajima, et al. Expression of leukotriene B4 receptor 1 defines functionally distinct DCs that control allergic skin inflammation. Cellular & molecular immunology. 2020
  • Mitsuyoshi Nakao, Hiroshi Tanaka, Tomoaki Koga. Cellular Senescence Variation by Metabolic and Epigenomic Remodeling. Trends in cell biology. 2020
  • Hirotsugu Uzawa, Daisuke Kohno, Tomoaki Koga, Tsutomu Sasaki, Ayako Fukunaka, Toshiaki Okuno, Airi Jo-Watanabe, Saiko Kazuno, Takeshi Miyatsuka, Tadahiro Kitamura, et al. Leukotriene A4 hydrolase deficiency protects mice from diet-induced obesity by increasing energy expenditure through neuroendocrine axis. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2020
  • Hiroshi Tanaka, Tomoka Igata, Kan Etoh, Tomoaki Koga, Shin-Ichiro Takebayashi, Mitsuyoshi Nakao. The NSD2/WHSC1/MMSET methyltransferase prevents cellular senescence-associated epigenomic remodeling. Aging cell. 2020
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MISC (50):
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Books (3):
  • Clinical Immunology & Allergy
    2018
  • Bioactive Lipid Mediators
    Springer Japan 2015
  • 疾患モデルの作製と利用ー脂質代謝異常と関連疾患ー
    LIC出版 2015
Lectures and oral presentations  (4):
  • ロイコトリエンB4とその受容体BLT1による樹状細胞の機能制御
    (第43回日本分子生物学会フォーラム「脂質多様性を基軸とした炎症・免疫制御」 2020)
  • Regulation of monocytic cell subsets by lipid mediator and epigenome
    (2019)
  • 生理活性脂質ロイコトリエンB4受容体BLT1による生体防御応答
    (第7回 オルソオルガノジェネシス検討会 2017)
  • BLT1 as a marker for novel dendritic subset
    (2014)
Professional career (1):
  • 博士(薬学) (熊本大学)
Association Membership(s) (6):
日本脂質免疫学研究会 ,  日本免疫学会 ,  日本脂質生化学会 ,  日本エピジェネティクス研究会 ,  日本生化学会 ,  日本分子生物学会
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