Rchr
J-GLOBAL ID:201601015692200110   Update date: Feb. 20, 2024

Uehata Takuya

ウエハタ タクヤ | Uehata Takuya
Affiliation and department:
Research field  (1): Immunology
Research keywords  (2): T細胞活性化制御 ,  RNA分解
Research theme for competitive and other funds  (6):
  • 2020 - 2025 Biophysical Chemistry for Material Symbiosis
  • 2020 - 2025 Identification of Symbiotic Communication between Artificial Nucleic Acids and Human Immune Systems
  • 2021 - 2024 mRNA分解酵素Regnase-1の新規ユビキチン化を介した免疫制御機構の解明
  • 2018 - 2023 Analysis of immune regulatory mechanisms mediated by mRNA metabolism
  • 2018 - 2021 Elucidation of a novel posttranscriptional mechanism regulating early lymphopoiesis
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Papers (31):
  • Takuya Uehata, Shinnosuke Yamada, Daisuke Ori, Alexis Vandenbon, Amir Giladi, Adam Jelinski, Yasuhiro Murakawa, Hitomi Watanabe, Kazuhiro Takeuchi, Kazunori Toratani, et al. Regulation of lymphoid-myeloid lineage bias through Regnase-1/3-mediated control of Nfkbiz. Blood. 2023
  • Ai Yaku, Tadakatsu Inagaki, Ryotaro Asano, Makoto Okazawa, Hiroyoshi Mori, Ayuko Sato, Fabian Hia, Takeshi Masaki, Yusuke Manabe, Tomohiko Ishibashi, et al. Regnase-1 Prevents Pulmonary Arterial Hypertension Through mRNA Degradation of Interleukin-6 and Platelet-Derived Growth Factor in Alveolar Macrophages. Circulation. 2022. 146. 13. 1006-1022
  • Aki Ejima, Shinya Abe, Akihiro Shimba, Susumu Sato, Takuya Uehata, Shizue Tani-Ichi, Satoru Munakata, Guangwei Cui, Osamu Takeuchi, Toyohiro Hirai, et al. Androgens Alleviate Allergic Airway Inflammation by Suppressing Cytokine Production in Th2 Cells. Journal of immunology (Baltimore, Md. : 1950). 2022. 209. 6. 1083-1094
  • Ka Man Tse, Alexis Vandenbon, Xiaotong Cui, Takashi Mino, Takuya Uehata, Keiko Yasuda, Ayuko Sato, Tohru Tsujimura, Fabian Hia, Masanori Yoshinaga, et al. Enhancement of Regnase-1 expression with stem loop-targeting antisense oligonucleotides alleviates inflammatory diseases. Science translational medicine. 2022. 14. 644. eabo2137
  • Yee Kien Chong, Sarang Tartey, Yuki Yoshikawa, Koshi Imami, Songling Li, Masanori Yoshinaga, Ai Hirabayashi, Guohao Liu, Alexis Vandenbon, Fabian Hia, et al. Cyclin J-CDK complexes limit innate immune responses by reducing proinflammatory changes in macrophage metabolism. Science signaling. 2022. 15. 729. eabm5011
more...
MISC (1):
  • Yoshinari Nakatsuka, Takashi Mino, Masanori Yoshinaga, Takuya Uehata, Atsuyasu Sato, Tomohiro Handa, Kazuo Chin, Toyohiro Hirai Hirai, Osamu Takeuchi. Pulmonary Regnase-1 functions as a posttranscriptional switch in anti-bacterial immunity. CYTOKINE. 2017. 100. 39-39
Education (1):
  • 1998 - 2004 Osaka University Faculty of Medicine Medical School
Association Membership(s) (4):
日本分子生物学会 ,  日本免疫学会 ,  日本腎臓学会 ,  日本内科学会
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