Abe Takayuki

Research field (4)： Molecular biology , Immunology , Gastroenterology , Virology

Research theme for competitive and other funds (15)：

2022 - 2025 Study of hepatitis B virus propagation and drug discovery research using the reporter HBV system
2022 - 2024 Basic study of a novel therapy against SARS-CoV-2 infection.
2021 - 2024 Basic study of a novel therapy against SARS-CoV-2 infection.
2020 - 2022 Analysis of HBV life cycle and drug discovery research using a reporter HBV
2017 - 2020 肝炎ウイルスの増殖制御に関わる細胞内アネキシン分子の機能解析

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Papers (75)：

Lin Deng, Muchamad Ridotu Solichin, Dewa Nyoman Murti Adyaksa, Maria Alethea Septianastiti, Rhamadianti Aulia Fitri, Gede Ngurah Rsi Suwardan, Chieko Matsui, Takayuki Abe, Ikuo Shoji. Cellular Release of Infectious Hepatitis C Virus Particles via Endosomal Pathways. Viruses. 2023. 15. 12
Adi Ariffianto, Lin Deng, Takayuki Abe, Chieko Matsui, Masahiko Ito, Akihide Ryo, Hussein Hassan Aly, Koichi Watashi, Tetsuro Suzuki, Masashi Mizokami, et al. Oxidative stress sensor Keap1 recognizes HBx protein to activate the Nrf2/ARE signaling pathway, thereby inhibiting hepatitis B virus replication. Journal of virology. 2023. 97. 10. e0128723
Juniastuti, Takako Utsumi, Laura Navika Yamani, Zayyin Dinana, Emily Gunawan, Aussie Tahta Maharani, Anisa Lailatul Fitria, Rury M Wahyuni, Soetjipto, Yen Hai Doan, et al. A household survey of intrafamily norovirus transmission. Journal of medical virology. 2023. 95. 10. e29164
Adi Ariffianto, Lin Deng, Saki Harada, Yujiao Liang, Chieko Matsui, Takayuki Abe, Ikuo Shoji. Transcription Factor JunB Suppresses Hepatitis C Virus Replication. The Kobe journal of medical sciences. 2023. 69. 3. E86-E95
Takayuki Abe, Yuki Marutani, Lin Deng, Chieko Matsui, Masayoshi Fukasawa, Ryosuke Suzuki, Takaji Wakita, Yoshiharu Matsuura, Ikuo Shoji. Hepatitis C Virus Disrupts Annexin 5-Mediated Occludin Integrity through Downregulation of Protein Kinase Cα (PKCα) and PKCη Expression, Thereby Promoting Viral Propagation. Journal of virology. 2023. 97. 6. e0065523

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MISC (9)：

Baculovirus vaccines. 2013. 60. 5. 568-575
Xiaoyu Wen, Takayuki Abe, Kohji Moriishi, Yoshiharu Matsuura. ELIMINATION OF HCV FROM HUMAN HEPATOCYTES BY INDUCTION OF TYPE I IFN VIA EXPRESSION OF IRF7. JOURNAL OF GENE MEDICINE. 2009. 11. 12. 1165-1166
北島雅之, 阿部隆之, 黒崎直子, 谷口克, 中山俊憲, 高久洋. AcMNPVによるNK細胞依存的抗腫瘍免疫の誘導. 日本癌学会総会記事. 2006. 65回. 458-458
阿部隆之, 谷英樹, 松永朋子, 林昌宏, 宮本大伸, 森嘉生, 森石恆司, 松浦善治. 【ワクチンの免疫効果の増強法と誘導免疫の特性】ワクチンベクターとしてのバキュロウイルス. 臨床免疫. 2005. 43. 6. 652-658
谷英樹, 阿部隆之, 林昌宏, 望月理加, 山岸潤也, 北川善紀, 渡辺理恵, 宮本大伸, 森石恆司, 松浦善治. 【ウイルスベクター最新の話題】バキュロウイルスベクター哺乳動物細胞への遺伝子導入. ウイルス. 2003. 53. 2. 185-193

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Books (14)：

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Lectures and oral presentations (76)：

HCV infection disrupts the ANX5-mediated occludin integrity through the downregulation of PKCη expression to promote viral propagation.
(第69回日本ウイルス学会学術集会 2022)
A novel bile acid derivative inhibits HBV infection via sodium taurocholate co-transporting polypeptide.
(第69回日本ウイルス学会学術集会)
SARS-CoV-2 papain-like protease counteracts ISGylation-mediated antiviral activity by sequestering ISGylated viral nucleocapsid protein.
(第69回日本ウイルス学会学術集会)
A novel bile acid derivative inhibits HBV infection via sodium taurocholate co-transporting polypeptide.
(2022 International HBV Meeting 2022)
SARS-CoV-2 papain-like protease counteracts ISGylation-mediated antiviral activity by sequestering ISGylated viral nucleocapsid protein.
(2022 The 20th Awaji International Forum on Infection and Immunity 2022)

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Education (1)：

Professional career (2)：

Committee career (3)：

2022/03 - 現在 The Japanese Society for Virology Director
2020/04 - 現在日本ウイルス学会ウイルス編集委員会
2020/04 - 現在 The Japanese Society for Virology Councilor of the Japanese Society of Virology

Awards (1)：

Association Membership(s) (1)：

The Japanese Society For Virology

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