Abe Takayuki

Research field (4)： Molecular biology , Immunology , Gastroenterology , Virology

Research theme for competitive and other funds (16)：

2022 - 2025 Study of hepatitis B virus propagation and drug discovery research using the reporter HBV system
2024 - Development of basic research technology necessary to overcome Parechovirus A3 infection
2022 - 2024 Basic study of a novel therapy against SARS-CoV-2 infection.
2021 - 2024 Basic study of a novel therapy against SARS-CoV-2 infection.
2020 - 2022 Analysis of HBV life cycle and drug discovery research using a reporter HBV

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Papers (78)：

Aulia Fitri Rhamadianti, Takayuki Abe, Tomohisa Tanaka, Chikako Ono, Hisashi Katayama, Yoshiteru Makino, Lin Deng, Chieko Matsui, Kohji Moriishi, Fumi Shima, et al. SARS-CoV-2 papain-like protease inhibits ISGylation of the viral nucleocapsid protein to evade host anti-viral immunity. Journal of virology. 2024. 98. 9. e0085524
Lin Deng, Muchamad Ridotu Solichin, Dewa Nyoman Murti Adyaksa, Maria Alethea Septianastiti, Rhamadianti Aulia Fitri, Gede Ngurah Rsi Suwardan, Chieko Matsui, Takayuki Abe, Ikuo Shoji. Cellular Release of Infectious Hepatitis C Virus Particles via Endosomal Pathways. Viruses. 2023. 15. 12
Adi Ariffianto, Lin Deng, Takayuki Abe, Chieko Matsui, Masahiko Ito, Akihide Ryo, Hussein Hassan Aly, Koichi Watashi, Tetsuro Suzuki, Masashi Mizokami, et al. Oxidative stress sensor Keap1 recognizes HBx protein to activate the Nrf2/ARE signaling pathway, thereby inhibiting hepatitis B virus replication. Journal of virology. 2023. 97. 10. e0128723
Juniastuti, Takako Utsumi, Laura Navika Yamani, Zayyin Dinana, Emily Gunawan, Aussie Tahta Maharani, Anisa Lailatul Fitria, Rury M Wahyuni, Soetjipto, Yen Hai Doan, et al. A household survey of intrafamily norovirus transmission. Journal of medical virology. 2023. 95. 10. e29164
Adi Ariffianto, Lin Deng, Saki Harada, Yujiao Liang, Chieko Matsui, Takayuki Abe, Ikuo Shoji. Transcription Factor JunB Suppresses Hepatitis C Virus Replication. The Kobe journal of medical sciences. 2023. 69. 3. E86-E95

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MISC (16)：

阿部隆之, 松井千絵子, とう琳, 松浦善治, 勝二郁夫. HCV感染はANX5とPKC-etaによるoccludinの機能制御に干渉することでウイルス伝播を促進させる. 日本ウイルス学会学術集会プログラム・予稿集(Web). 2022. 69th
阿部隆之, 松井千絵子, DENG Lin, 松浦善治, 勝二郁夫. 細胞内アネキシン5はC型肝炎ウイルスの増殖抑制に関与する. 日本分子生物学会年会プログラム・要旨集(Web). 2020. 43rd
松井千絵子, YULIANDARI Putu, DENG Lin, 阿部隆之, 勝二郁夫. HCV NS3/4AプロテアーゼはSPG20を選択的に切断し脂肪滴の巨大化を促進する. 日本分子生物学会年会プログラム・要旨集(Web). 2020. 43rd
松井千絵子, PUTU Yuliandari, LIN Deng, 阿部隆之, 勝二郁夫. HCV NS3/4AプロテアーゼはSPG20を選択的に切断し脂肪滴の巨大化を促進する. 日本ウイルス学会学術集会プログラム・予稿集(Web). 2019. 67th
阿部隆之, 松井千絵子, LIN Deng, 福原崇介, 松浦善治, 勝二郁夫. C型肝炎ウイルスNS5A蛋白質のISGylation修飾反応におけるウイルス遺伝子型間の解析. 日本ウイルス学会学術集会プログラム・予稿集(Web). 2019. 67th

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Books (14)：

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Lectures and oral presentations (76)：

HCV infection disrupts the ANX5-mediated occludin integrity through the downregulation of PKCη expression to promote viral propagation.
(第69回日本ウイルス学会学術集会 2022)
A novel bile acid derivative inhibits HBV infection via sodium taurocholate co-transporting polypeptide.
(第69回日本ウイルス学会学術集会)
SARS-CoV-2 papain-like protease counteracts ISGylation-mediated antiviral activity by sequestering ISGylated viral nucleocapsid protein.
(第69回日本ウイルス学会学術集会)
A novel bile acid derivative inhibits HBV infection via sodium taurocholate co-transporting polypeptide.
(2022 International HBV Meeting 2022)
SARS-CoV-2 papain-like protease counteracts ISGylation-mediated antiviral activity by sequestering ISGylated viral nucleocapsid protein.
(2022 The 20th Awaji International Forum on Infection and Immunity 2022)

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Education (1)：

Professional career (2)：

Work history (4)：

Committee career (3)：

2022/03 - 現在 The Japanese Society for Virology Director
2020/04 - 現在日本ウイルス学会ウイルス編集委員会
2020/04 - 現在 The Japanese Society for Virology Councilor of the Japanese Society of Virology

Awards (1)：

Association Membership(s) (1)：

The Japanese Society For Virology

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