Rchr
J-GLOBAL ID:201601017072108349   Update date: Feb. 01, 2024

Kikuchi Hidetomo

キクチ ヒデトモ | Kikuchi Hidetomo
Affiliation and department:
Job title: Assistant Professor
Homepage URL  (1): https://scholar.google.com/citations?user=DCZYwe8AAAAJ&hl=en
Research field  (6): Pharmacology ,  Tumor biology ,  Pharmaceuticals - health and biochemistry ,  Home economics, lifestyle science ,  Biological, health, and medical informatics ,  Science education
Research keywords  (9): Cancer ,  Lifestyle disease ,  Dihydropyrimidine ,  Natural products ,  Flavonoid ,  Cell homeostasis ,  Computer Science ,  Functional foods ,  Food-Drug interaction
Research theme for competitive and other funds  (6):
  • 2020 - 2023 Fundamental research of antitumor activity of arsenic compound in combination with active bufadienolide compounds against glioblastoma cells
  • 2018 - 2020 食品と医薬品の相互作用情報にもとづいたメニュー開発と健康情報の発信に関する研究
  • 2018 - 2020 ヒト肝キメラマウスを用いたカクテル基質試験法による食品-医薬品相互作用の網羅的解析の確立を目指した基盤研究
  • 2017 - 2019 コラーゲンペプチドの脳神経細胞および脳マーカーに与える影響
  • 2016 - 2019 Development of novel dihydropyrimidine retinoids for medicinal chemistry and drug dicovery
Show all
Papers (22):
  • Bo Yuan, Hidetomo Kikuchi, Jingmei Li, Atsushi Kawabata, Kozo Yao, Norio Takagi, Mari Okazaki. Cytotoxic Effects of Darinaparsin, a Novel Organic Arsenical, against Human Leukemia Cells. International Journal of Molecular Sciences. 2023. 24. 3. 2282-2282
  • Bo Yuan, Jingmei Li, Shin-Ichi Miyashita, Hidetomo Kikuchi, Meiyan Xuan, Hirokazu Matsuzaki, Naohiro Iwata, Shinya Kamiuchi, Katsuyoshi Sunaga, Yasuhide Hibino, et al. Enhanced cytotoxic effects of arenite in combination with active bufadienolide compounds against human glioblastoma cell line U-87. Molecules. 2022. 27. 19. 6577-6577
  • Yoshio Nishimura, Hidetomo Kikuchi, Takanori Kubo, Rie Arai, Yuki Toguchi, Bo Yuan, Katsuyoshi Sunaga, Hidetsura Cho. Synthesis of 4,4-Disubstituted 3,4-Dihydropyrimidin-2(1H)-ones and -thiones, the Corresponding Products of Biginelli Reaction Using Ketone, and Their Antiproliferative Effect on HL-60 Cells. Chemical and Pharmaceutical Bulletin. 2022. 70. 2. 111-119
  • Tadasuke Nozaki, Masayuki Takahashi, Tatsuya Ishikawa, Arisa Haino, Mineaki Seki, Hidetomo Kikuchi, Bo Yuan, Masayuki Nashimoto. The heptamer sgRNA targeting the human OCT4 mRNA can upregulate the OCT4 expression. Biochemistry and Biophysics Reports. 2021. 26. 100918-100918
  • Yoshio Nishimura, Hidetomo Kikuchi, Takanori Kubo, Ibuki Nakakita, Mari Ogunia, Misaki Ohta, Rie Arai, Bo Yuan, Katsuyoshi Sunaga, Hidetsura Cho. Synthesis of novel 6-unsubstituted 2-aminodihydropyrimidines by Sc(OTf)3-mediated amination and their antiproliferative effect on HL-60 cells. Tetrahedron Letters. 2021. 65. 152760-152760
more...
MISC (16):
  • Katsuyoshi Sunaga, Hidetomo Kikuchi. Interactions between foods and drugs. New Food Industry. 2022. 64. 11. 709-723
  • Hidetomo Kikuchi, Rie Arai, Shiori Yoshida, Naohiro Iwata. Statistical Analysis of Text on National Examination for Registered Dietitian - An example study at the area of “nutrition of carbohydrates” in basic nutrition -. Josai Information Sciences Researches. 2022. 29. 1. 38-49
  • KIKUCHI, Hidetomo, IWATA, Naohiro, ARAI, Rie. An example of giving an online lecture utilizing the “Microsoft Teams” -A case of “Pharmacotherapy A”, a specialized subject in the course of Clinical Nutrition, Department of Clinical Dietetics and Human Nutrition, Faculty of Pharmacy and Pharmaceutical Sciences-. JOSAI INFORMATION SCIENCES RESEARCHES. 2021. 28. 1. 8-15
  • KIKUCHI, Hidetomo, IWATA, Naohiro, UCHIDA, Hiroyuki, SHIMIZU, Jun, IGARASHI, Mamoru, KAMIUCHI, Shinya, ITO, Junta, MANO, Hiroshi. Approach of online measures for “Practicum in Multidiscipline A” in the latter sophomore course of Clinical Nutrition, Department of Clinical Dietetics and Human Nutrition, Faculty of Pharmacy and Pharmaceutical Sciences. JOSAI INFORMATION SCIENCES RESEARCHES. 2021. 28. 1. 1-7
  • 須永 克佳, 菊地 秀与. 大学通信 Vol.139 薬物療法学研究室紹介. 埼玉県薬剤師会雑誌. 2020. 46. 7. 7-11
more...
Patents (4):
  • BRAIN FUNCTION REGULATING AGENT, AND FOOD OR BEVERAGE PRODUCT CONTAINING SAME
  • BRAIN FUNCTION REGULATING AGENT, AND FOOD OR BEVERAGE PRODUCT CONTAINING SAME
  • BRAIN FUNCTION REGULATOR, AND FOOD OR BEVERAGE CONTAINING SAME
  • BRAIN FUNCTION REGULATING AGENT, AND FOOD OR BEVERAGE PRODUCT CONTAINING SAME
Books (3):
  • 患者さん目線から考える がんの栄養・食事ガイドブック
    メディカルレビュー社 2017
  • 管理栄養士過去問ここだけ丸暗記
    技術評論社 2016
  • 管理栄養士国家試験対策問題集
    技術評論社 2015
Lectures and oral presentations  (49):
  • Differentiation inducing effect of ATRA in combination with 2-methylthio dihydropyrimidine on human leukemia NB4 cells
    (The 143rd Annual Meeting of the Pharmaceutical Society of Japan (Sapporo) 2023)
  • Involvement of Caspases and MAP kinase in 2-methylthio dihydropyrimidine-triggered cytotoxicity against human leukemia NB4 cells
    (The 143rd Annual Meeting of the Pharmaceutical Society of Japan (Sapporo) 2023)
  • Enhanced cytotoxicity of arenite combinated with bufadienolides against human glioblastoma cell line U-87
    (The 143rd Annual Meeting of the Pharmaceutical Society of Japan (Sapporo) 2023)
  • ヒトOCT4 mRNAを標的とするheptamer型sgRNAはOCT4の発現を上昇させることができる
    (第26回 日本バイオ治療法学会学術集会 2022)
  • ICTを活用したがん患者向けメニュー開発参加が管理栄養士養成施設学生の社会人基礎力及び専門力に与える影響
    (第69回日本栄養改善学会学術総会 2022)
more...
Works (1):
  • 食用ハーブと薬の相互作用
    菊地 秀与 2023 - 2023
Education (3):
  • 2007 - 2010 Tokyo University of Pharmacy and Life Sciences Graduate School of Pharmacy Doctor's program
  • 2005 - 2007 Tokyo University of Pharmacy and Life Sciences Graduate School of Pharmacy Master's program
  • 2000 - 2004 Tokyo University of Pharmacy and Life Sciences School of Pharmacy
Professional career (1):
  • Doctor of Pharmacy (Tokyo University of Pharmacy and Life Sciences)
Work history (3):
  • 2020/04 - 現在 Josai University Faculty of Pharmaceutical Sciences Department of Clinical Dietetics and Human Nutrition Associate professor
  • 2014/04 - 2020/03 Josai University Department of Clinical Dietetics and Human Nutrition, Faculty of Pharmacy and Pharmaceutical Sciences Assistant professor
  • 2011/04 - 2014/03 Yasuda Women's University Faculty of Pharmacy, Department of Pharmacy Research associate
Association Membership(s) (4):
Japan Society for Science Education ,  The Japanese Biochemical Society ,  Japan Society of Histochemistry and Cytochemistry ,  The Pharmaceutical Society of Japan
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