2020 - 2022 Empirical study on Pareto efficiency related to industry, medical care and insurance in anti-cancer drug treatment
2019 - 2022 Development of non-viral vector to realize treatment of hereditary disease using genome editing RNA technology
2018 - 2022 Establishing novel molecular-targeted cancer therapies based on molecular diagnostics focusing on prognostic factor CYLD
2017 - 2021 Search for uremia suppressive therapeutics based on investigation on role of sulfate-conjugated uremic solutes in development and pregoression of kidney injury
2017 - 2019 Potential use of multifunctional polyamidoamine Dendrimer for curative treatments of intractable amyloidoses
2014 - 2018 Elucidating clinical significance of CYLD down-regulation for establishing individualized cancer therapy
2015 - 2017 Development of novel multi-target drugs for intractable amyloidoses
2013 - 2017 Development of renoprotective and uremia therapeutic drug seeds based on inhibition of hepatic production of sulfate-conjugated uremic solutes
2013 - 2016 Establishment of hepatocyte model from induced pluripotent stem (iPS) cells for exploring uremic toxin production inhibitors
2012 - 2015 Early diagnosis and analyses of the pathogenesis for amyloidosis with all our previous investigations
2011 - 2013 Novel roles of chronic inflammatory factor CYLD in lung fibrosis
2011 - 2012 Analysis of autoantibodies for targeting pathogenesis and therapyof misfolding diseases
2012 - 化学療法薬の体内動態インフォメーションに基づく個別投与設計法に関する研究
2012 - 腎機能障害に伴う病態進展因子群と薬物動態変動に関する基礎・臨床研究
2009 - 2011 Hepatocyte replacement therapy for familial amybidotic polyneuropathy combining iPS cells and gene-repair therapy
2008 - 2010 Novel roles of CYLD in the molecular pathogenesis of intractable diseases
2008 - 癌の病態解析とバイオマーカー探索および新規治療法の開発
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Papers (183)：
Kazutaka Oda, Tomomi Katanoda, Hitomi Arakaki, Taiki Katsume, Kaho Matsuyama, Hirofumi Jono, Hideyuki Saito. Thiamylal serum concentration for refractory convulsive status epilepticus while associated decreased concentrations of concomitant antiepileptics: a case report. Journal of pharmaceutical health care and sciences. 2024. 10. 1. 39-39
Junji Saruwatari, Tetsuya Kaneko, Tsukasa Murata, Haruka Narise, Sawa Kugimoto, Eri Nishimura, Natsuki Tetsuka, Misaki Ando, Momo Oi, Masako Ota, et al. Effect of concomitant use of yokukansan on steady-state blood concentrations of donepezil and risperidone in real-world clinical practice. Neuropsychopharmacology reports. 2024
Kazutaka Oda, Hirofumi Jono, Hideyuki Saito. Optimizing Cefiderocol Dosing Through Population Pharmacokinetic/Pharmacodynamic Simulation: An Assessment of Drug Cost Reductions. Therapeutic drug monitoring. 2024
Kazutaka Oda, Kazuaki Matsumoto, Kensuke Shoji, Akari Shigemi, Hideki Kawamura, Yoshiko Takahashi, Tomomi Katanoda, Yumi Hashiguchi, Hirofumi Jono, Hideyuki Saito, et al. Validation and development of population pharmacokinetic model of vancomycin using a real-world database from a nationwide free web application. Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy. 2024
Kazutaka Oda, Hirofumi Jono, Hidenobu Kamohara, Hideyuki Saito. Population pharmacokinetic modeling of unbound meropenem in patients undergoing continuous renal replacement therapy: an observational cohort study. Therapeutid Drug Monitoring. 2024
猿渡淳二, 金子哲也, 金子哲也, 豎道真菜, 成瀬遥佳, 釘本沙和, 西村英里, 手束菜月, 安東実咲, 大井桃, et al. Effects of Yokukansan on the blood concentrations of donepezil and risperidone. 日本臨床精神神経薬理学会プログラム・抄録集. 2023. 33rd
成瀬遥佳, 金子哲也, 倉本佳奈, 釘本沙和, 西村英里, 渡邊誠司, 豎道真菜, 手束菜月, 安東実咲, 大井桃, et al. Effects of Yokukansan on the disposition of the antidementia drug donepezil hydrochloride and the antipsychotic drug risperidone. 日本薬学会年会要旨集(Web). 2023. 143rd
HOU Huixian, HORIKAWA Mai, NARITA Yuki, JONO Hirofumi, SAITO Hideyuki. Unilateral ureteral obstruction (UUO)-induced renal fibrosis is attenuated by suppression of indoxyl sulfate (IS) accumulation in sulfotransferase (Sult) 1a1-deficient mice. 日本腎臓学会誌(Web). 2023. 65. 3
新垣ひとみ, 桑野明香里, 平井ちか, 西郷智香, 金丸歩美, 林光博, 齋藤秀之, 齋藤秀之, 成田勇樹, 成田勇樹, et al. Novel drug therapy targeting NF-kB signal for triple-negative breast cancer patients with loss of CYLD expression. 日本薬学会年会要旨集(Web). 2023. 143rd
Tumor suppressor CYLD as a novel prognostic biomarker in primary breast cancer
(15th Congress of the International Association of Therapeutic Drug Monitoring & Clinical Toxicology 2017)
- 2003 Kumamoto University Graduate School, Division of Pharmaceutical Sciences
- 2003 Kumamoto University
- 1998 Kumamoto University Faculty of Pharmaceutical Science
- 1998 Kumamoto University School of Pharmacy
Professional career (2)：
Master of Pharmaceutical Science (Kumamoto University)
Doctor of Pharmaceutical Science (Kumamoto University)
Work history (5)：
2018 - 現在 熊本大学病院 臨床試験支援センター 副センター長
2012 - 現在 Kumamoto University Hospital University Hospital
2012 - 現在 Associate Professor, Kumamoto University Hospital
2008 - 2012 Kumamoto University Faculty of Life Sciences
2008 - 2012 Lecturer,Department of Molecular Laboratory Medicine,Faculty of Life Sciences(Clinical medicine group),Kumamoto University
Committee career (21)：
2023/04 - 現在 日本臨床化学会 法務委員会
2021/08 - 現在 一般社団法人TDM品質管理機構 評価委員会委員
2021/04 - 現在 公益社団法人 日本薬学会 代議員
2021/04 - 現在 日本臨床化学会 学会賞選考委員会
2021/04 - 現在 日本臨床化学会 教育委員会
2021/04 - 現在 日本臨床化学会 理事
2021/04 - 現在 日本臨床化学会 編集委員会・編集委員長
2020/07 - 現在 Japanese Society of Pharmaceutical Health Care and Sciences JPHCS Editorial Committee
2020/07 - 現在 Japanese Society of Pharmaceutical Health Care and Sciences Public Relations and Publishing Committee
2020/07 - 現在 Japanese Society of Pharmaceutical Health Care and Sciences Committee of General Purpose
2019/03 - 現在 Japanese Society of Pharmaceutical Health Care and Sciences Representative
2018 - 現在 日本薬理学会 学術評議員
2015 - 現在 日本臨床化学会 広報委員
2013 - 現在 日本臨床化学会 評議委員
2012 - 現在 熊本県病院薬剤師会 理事
2012 - 現在 熊本県病院薬剤師会 実務実習教育委員長
2011/04 - 現在 日本臨床化学会 編集委員
2008 - 現在 九州遺伝子診断研究会 世話人
2008 - 現在 日本臨床化学会 九州支部評議員
2019/04 - 2021/03 日本臨床化学会 編集副委員長
2012 - 熊本県病院薬剤師会 編集委員長
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Awards (9)：
2022/11 - 熊本大学特別表彰(医療活動表彰)
2019/11 - 熊本大学研究活動表彰
2019/09 - 一般社団法人日本臨床化学会 一般社団法人日本臨床化学会 学術賞
2018/11 - 熊本大学研究活動表彰
2018 - 熊本大学教育活動表彰
2017/11 - 熊本大学研究活動表彰
2016 - 日本薬学会九州支部 学術奨励賞
2015 - 一般社団法人日本臨床化学会 奨励賞
2011 - 熊本大学特別表彰(医療活動表彰)
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Association Membership(s) (9)：
日本ゲノム薬理学会
, 日本TDM学会
, 日本臨床化学会 評議委員
, 日本病院薬剤師会
, 日本医療薬学会
, Japanese Society of Pharmacogenomics
, The Japanese Society of Therapeutic Drug Monitoring
, Japanese Society of Hospital Pharmacists
, International Society of Amyloidosis
