2020 - 2022 Significance of CTGF for naturetic-peptide effects on high salt and aldosterone-induced renal injury
2018 - 2020 The impact of CTGF on glomerular injury in diabetic mice fed high fat, high protein or high salt diet
Papers (125):
Takuya Ishimura, Akira Ishii, Hiroyuki Yamada, Keisuke Osaki, Naohiro Toda, Keita P Mori, Shoko Ohno, Yukiko Kato, Takaya Handa, Sayaka Sugioka, et al. Matrix metalloproteinase-10 deficiency has protective effects against peritoneal inflammation and fibrosis via transcription factor NFκΒ pathway inhibition. Kidney international. 2023
Ryota Akagi, Akira Ishii, Keiichi Kaneko, Naoya Kondo, Hideki Yokoi, Takeshi Matsubara, Sachiko Minamiguchi, Yoshihiko Kanno, Motoko Yanagita. A report of three cases of patients with tubulointerstitial nephritis with IgM-positive plasma cells, treatment, and serum-IgM as a sensitive marker for relapse. BMC Nephrology. 2023. 24. 1
Sayaka Sugioka, Hiroyuki Yamada, Akira Ishii, Yukiko Kato, Ryo Yamada, Keita P Mori, Shoko Ohno, Takaya Handa, Akie Ikushima, Takuya Ishimura, et al. Dual deletion of guanylyl cyclase-A and p38 mitogen-activated protein kinase in podocytes with aldosterone administration causes glomerular intra-capillary thrombi. Kidney international. 2023
Haruomi Nishio, Akira Ishii, Hiroyuki Yamada, Keita P Mori, Yukiko Kato, Shoko Ohno, Takaya Handa, Sayaka Sugioka, Takuya Ishimura, Akie Ikushima, et al. Sacubitril/valsartan ameliorates renal tubulointerstitial injury through increasing renal plasma flow in a mouse model of type 2 diabetes with aldosterone excess. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. 2023
Circulating NGAL accelerates diet-induced obesity through local inhibition of thermogenic beta3 adrenergic nerve/brown adipose tissue axis.
(the 18th World Congress of Basic and Clinical Pharmacology (WCP2018) 2018)