J-GLOBAL ID:201601019036967591   Update date: Sep. 05, 2023

Sugino Shigekazu

スギノ シゲカズ | Sugino Shigekazu
Affiliation and department:
Job title: Associate Professor
Other affiliations (1):
Research field  (1): Anesthesiology
Research keywords  (12): NK1 receptor ,  G-protein coupling receptor ,  Next-generation DNA sequencer ,  Genome-wide association study ,  chronic post-surgical pain ,  Omics ,  Suncus ,  Nausea and Vomiting ,  Opioid ,  Perioperative Genetics and Genomics ,  Pain ,  Anesthesiology
Research theme for competitive and other funds  (22):
  • 2023 - 2026 新しいラットモデルを用いた術後痛遷延化の分子遺伝メカニズムの解明と治療戦略の開発
  • 2021 - 2026 Suncus Research for Elucidating the Genetic Mechanism in Postoperative Nausea and Vomiting
  • 2022 - 2025 Quantification of Nociceptive Pain by EEG Gamma Oscillations in the Primary Somatosensory Cortex for Precision Postoperative Analgesia
  • 2021 - 2025 Novel Rat Model and Intervention for Elucidating the Molecular Mechanism in Chronic Postsurgical Pain
  • 2021 - 2024 Development of Adverse Events-free Local Anesthetics in Cryo-EM Structural Determination of Sodium Channels
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Papers (54):
  • Yudai Iwasaki, Yusuke Takei, Mitsuhiro Yamada, Shigekazu Sugino, Koji Saito, Tetsuji Aoyagi, Kengo Oshima, Hajime Kanamori, Hiroaki Baba, Kentarou Takei, et al. Circulating Extracellular Vesicle Levels in Patients with Coronavirus Disease 2019 Coagulopathy: A Prospective Cohort Study. Journal of clinical medicine. 2023. 12. 10
  • Kotoe Kamata, Suguru Asagi, Yoshiteru Shimoda, Masayuki Kanamori, Nozomu Abe, Shigekazu Sugino, Teiji Tominaga, Masanori Yamauchi. Successful recording of direct cortical motor-evoked potential from a pediatric patient under remimazolam anesthesia: a case report. JA Clinical Reports. 2022. 8. 1
  • Eiko Onishi, Kazutomo Saito, Michio Kumagai, Ruri Oba, Toru Murakami, Shigekazu Sugino, Masanori Yamauchi. Evaluation of contrast-enhanced ultrasonography with Sonazoid® in visualization of local anesthetic distribution in rectus sheath block: a prospective, clinical study. Journal of anesthesia. 2022. 36. 3. 405-412
  • Daisuke Konno, Shigekazu Sugino, Tomoko F Shibata, Kazuharu Misawa, Yuka Imamura-Kawasawa, Jun Suzuki, Kanta Kido, Masao Nagasaki, Masanori Yamauchi. Antiemetic effects of baclofen in a shrew model of postoperative nausea and vomiting: Whole-transcriptome analysis in the nucleus of the solitary tract. CNS neuroscience & therapeutics. 2022. 28. 6. 922-931
  • Hidehisa Saito, Shizu Hidema, Ayano Otsuka, Jun Suzuki, Michio Kumagai, Akihiro Kanaya, Toru Murakami, Yusuke Takei, Kazutomo Saito, Shigekazu Sugino, et al. Effects of oxytocin on responses to nociceptive and non-nociceptive stimulation in the upper central nervous system. Biochemical and biophysical research communications. 2021. 574. 8-13
MISC (100):
  • 武井 祐介, 岩崎 夢大, 紺野 大輔, 入間田 大介, 関根 智宏, 齋藤 秀悠, 杉野 繁一, 鈴木 潤, 山内 正憲. 細胞外小胞に着目した人工呼吸関連肺傷害の内皮傷害マーカーの探索. 日本集中治療医学会雑誌. 2023. 30. Suppl.1. S579-S579
  • 鈴木 潤, 杉野 繁一, 齋藤 秀悠, 本間 舞子, 山内 正憲. 臨床に即した遷延性術後痛モデル動物の開発とtranscriptome profiling. 日本ペインクリニック学会誌. 2023. 30. 5. 120-121
  • 周 穎哲, 鎌田 ことえ, 杉野 繁一, 萩平 哲, 山内 正憲. 集中治療室における術後せん妄発症の危険因子. 日本老年麻酔学会プログラム・抄録集. 2023. 35回. 35-35
  • 高桑 こころ, 杉野 繁一, 齋藤 秀悠, 金谷 明浩, 茂木 章一郎, 山内 正憲. 剪断波速度を用いた筋緊張の定量化 麻酔導入時における前向き観察研究. 日本臨床麻酔学会誌. 2022. 42. 6. S181-S181
  • 杉野 繁一. 【痛みの精密医療の展開に向けて】全身麻酔後の悪心嘔吐と精密医療. Precision Medicine. 2022. 5. 2. 123-126
Lectures and oral presentations  (75):
  • Analgesic effect and safety of programmed intermittent bolus infusion concomitant with serratus anterior plane block for minimally invasive cardiac surgery: A randomized, double-blind controlled trial
    (Euroanaesthesia 2023 2023)
  • Learning curve to correct identification of the vertebral interspace for epidural puncture by ultrasound imaging validation
    (Euroanaesthesia 2023 2023)
  • Backcross of shrews for discovering genetic factors to prevent postoperative nausea and vomiting: a preliminary study
    (Euroanaesthesia 2023 2023)
  • Efficacy of programmed intermittent bolus infusion with serratus anterior plane block catheter for analgesia in the intensive care unit after minimally invasive cardiac surgery: A randomized, doubleblind, controlled trial
    (35th ESICM Annual Congress 2022)
  • Successful recording of direct cortical motor evoked potential from a paediatric patient under remimazolam anaesthesia
    (SSAI 2022 Congress 2022)
Education (2):
  • - 2008 Sapporo Medical University Graduate School of Medicine Anesthesiology
  • - 1998 Sapporo Medical University School of Medicine
Professional career (1):
  • Ph.D. (Sapporo Medical University)
Work history (13):
  • 2023/04 - 現在 Tohoku University Dept. of Anesthesiology and Perioperative Medicine Associate Professor
  • 2019/11 - 2023/03 Tohoku University Dept. of Anesthesiology and Perioperative Medicine Assistant Professor
  • 2015/07 - 2019/10 Tohoku University Dept. of Anesthesiology and Perioperative Medicine Research Associate
  • 2013/05 - 2015/06 Pennsylvania State University College of Medicine Dept. of Anesthesiology and Perioperative Medicine Visiting Research Asociate
  • 2010/04 - 2013/04 Sapporo Medical University Dept. of Anesthesiology Research Associate
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Awards (1):
  • JSA Hokkaido-Tohoku Branch 9th Annual Meeting Best Presentation Award Effect of Dexmedetomidine on A Rat Model of Postoperative Nausea and Vomiting
Association Membership(s) (6):
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