Rchr
J-GLOBAL ID:201601019036967591
Update date: Oct. 22, 2024
Sugino Shigekazu
スギノ シゲカズ | Sugino Shigekazu
Affiliation and department:
Job title:
Associate Professor
Other affiliations (1):
Research field (1):
Anesthesiology
Research keywords (19):
Anesthesiology
, Pain Medicine
, Perioperative Genetics and Genomics
, Opioid
, Postoperative Pain
, Acute Pain Service
, Chronic Post-surgical Pain
, Rat Model of Pain
, Postoperative Nausea and Vomiting
, Suncus
, Neuroanesthesia
, Awake Craniotomy
, Next-generation DNA Sequencer
, Genome-wide Association Study
, Transcriptome
, Omics
, Genetic Polymorphism
, Mass Spectrometry
, G-protein Coupling Receptor
Research theme for competitive and other funds (22):
- 2023 - 2026 新しいラットモデルを用いた術後痛遷延化の分子遺伝メカニズムの解明と治療戦略の開発
- 2021 - 2026 Suncus Research for Elucidating the Genetic Mechanism in Postoperative Nausea and Vomiting
- 2022 - 2025 Quantification of Nociceptive Pain by EEG Gamma Oscillations in the Primary Somatosensory Cortex for Precision Postoperative Analgesia
- 2021 - 2025 Novel Rat Model and Intervention for Elucidating the Molecular Mechanism in Chronic Postsurgical Pain
- 2021 - 2024 Development of Adverse Events-free Local Anesthetics in Cryo-EM Structural Determination of Sodium Channels
- 2021 - 2024 Single-cell Whole-transcriptome Analysis in Rat Basal Forebrain for Elucidating the Molecular Mechanism in Postoperative Delirium
- 2019 - 2022 Backcross of inbred Suncus for Elucidating the Genetic Mechanism in Postoperative Nausea and Vomiting
- 2019 - 2022 High-fat diet increases postoperative pain in rats
- 2020 - 2021 Treatment strategy for severe COVID-19 induced coagulopathy based on the specific mechanisms
- 2018 - 2021 Development of Multimodal Practice Guideline for Frozen Shoulder Focusing on Personalized Rehabilitation after Selective Nerve Block and Evaluation of Therapeutic Effects
- 2017 - 2021 Genome-wide linc RNA analysis in patients with neuropathic pain
- 2017 - 2020 Development of antiemetic drugs for PONV by genome-wide long non-coding RNAs analysis
- 2017 - 2019 Novel strategy for intensive care by using application of artificial intelligence to data mining of Diagnosis Procedure Combination payment system
- 2016 - 2019 補完的全ゲノム関連解析による小児の覚醒時興奮の分子基盤の解明
- 2016 - 2019 Galpha14-mediated NK1 receptor cell signaling in the celiac-superior mesenteric ganglion
- 2016 - 2019 Whole transcriptome analysis of the brain in a shrew model of postoperative nausea and vomiting
- 2013 - 2016 Analysis of cytoskeleton related genes in elderly patients
- 2012 - 2016 Determination of the molecular mechanism of volatile anesthetics using transcriptome analysis in thymo-cortico neurons of mice.
- 2011 - 2013 Association of epigenetic modulation in the TACR1 gene with opioid-induced nausea and vomiting
- 2011 - 2012 Association of genetic polymorphisms of the GABRB3 gene with the concentration of propofol at loss of consciousness
- 2008 - 2010 Establishment of Personalized Analgesia for Postoperative Pain
- 2006 - 2007 延髄痛覚受容ニューロン(RVMニューロン)の機能特性への遺伝的影響
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Papers (57):
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Yukie Nitta, Takuro Sanuki, Shigekazu Sugino, Masahiro Sugimoto, Kanta Kido. The Impact of Preoperative Psychiatric Intervention for Postoperative Delirium after Major Oral and Maxillofacial Surgery with Free Flap Reconstruction. Journal of stomatology, oral and maxillofacial surgery. 2024. 102026-102026
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Yutaka Kawano, Maki Tanaka, Yasushi Satoh, Shigekazu Sugino, Jun Suzuki, Masaki Fujishima, Eri Okumura, Hideo Takekoshi, Osamu Uehara, Shintaro Sugita, et al. Acanthopanax senticosus ameliorates steatohepatitis through HNF4 alpha pathway activation in mice. Scientific reports. 2024. 14. 1. 110-110
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Hidehisa Saito, Shigekazu Sugino, Shoichiro Moteki, Akihiro Kanaya, Masanori Yamauchi. Quantification of muscle tone by using shear wave velocity during an anaesthetic induction: a prospective observational study. BMC anesthesiology. 2023. 23. 1. 388-388
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Yudai Iwasaki, Yusuke Takei, Mitsuhiro Yamada, Shigekazu Sugino, Koji Saito, Tetsuji Aoyagi, Kengo Oshima, Hajime Kanamori, Hiroaki Baba, Kentarou Takei, et al. Circulating Extracellular Vesicle Levels in Patients with Coronavirus Disease 2019 Coagulopathy: A Prospective Cohort Study. Journal of clinical medicine. 2023. 12. 10
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Kotoe Kamata, Suguru Asagi, Yoshiteru Shimoda, Masayuki Kanamori, Nozomu Abe, Shigekazu Sugino, Teiji Tominaga, Masanori Yamauchi. Successful recording of direct cortical motor-evoked potential from a pediatric patient under remimazolam anesthesia: a case report. JA Clinical Reports. 2022. 8. 1
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MISC (113):
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星島宏, 宮崎智, 紺野大輔, 杉野繁一, 水田健太郎, 山内正憲. 人工知能による脊椎麻酔術後の悪心嘔吐のリスク因子の予測:観察研究. 日本麻酔科学会第71回学術集会. 2024
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合谷木諒, 杉野繁一, 矢吹志津葉, 本間舞子, 小野理恵, 山内正憲. 術後疼痛管理チームの介入を4日以上必要とした症例の分析. 日本麻酔科学会第71回学術集会. 2024
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杉野繁一, 山内正憲. 末梢神経ブロックに併用した高周波パルスの通電はFynチロシンキナーゼ発現を介して術後痛を減弱する. 日本区域麻酔学会第11回学術集会. 2024
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佐藤友菜, 熊谷道雄, 海法悠, 関根智宏, 杉野繁一, 井上洋, 伊藤淳, 山内正憲. 低侵襲心臓手術における前鋸筋面ブロックプログラム間欠投与の術後鎮痛効果:ランダム化比較試験. 第51回日本集中治療医学会学術集会. 2024
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鈴木潤, 本間舞子, 矢吹 志津葉, 小野理恵, 高野淳, 杉野繁一, 山内正憲. droperidolを併用したfentanylによる経静脈的患者自己調節鎮痛法の検討:単施設観察研究. 第51回日本集中治療医学会学術集会. 2024
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Lectures and oral presentations (80):
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The effects of a high-fat diet on a postoperative pain model in rat
(Euroanaesthesia 2024 2024)
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Gamma Oscillations of Electroencephalogram after Applications of Electrical Stimulation: A Preliminary Volunteer Study
(Euroanaesthesia 2024 2024)
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Factors affecting the occurence of fetal bradycardia after neuraxial labor analgesia: a retrospective observational study
(Euroanaesthesia 2024 2024)
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生成AIを基礎研究にどう組み込むのか?
(日本区域麻酔学会第11回学術集会 2024)
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PONV研究:過去・現在・未来
(日本区域麻酔学会第11回学術集会 2024)
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Education (2):
- - 2008 Sapporo Medical University Graduate School of Medicine Anesthesiology
- - 1998 Sapporo Medical University School of Medicine
Professional career (1):
- Ph.D. (Sapporo Medical University)
Work history (13):
- 2023/04 - 現在 Tohoku University Dept. of Anesthesiology and Perioperative Medicine Associate Professor
- 2019/11 - 2023/03 Tohoku University Dept. of Anesthesiology and Perioperative Medicine Assistant Professor
- 2015/07 - 2019/10 Tohoku University Dept. of Anesthesiology and Perioperative Medicine Research Associate
- 2013/05 - 2015/06 Pennsylvania State University College of Medicine Dept. of Anesthesiology and Perioperative Medicine Visiting Research Asociate
- 2010/04 - 2013/04 Sapporo Medical University Dept. of Anesthesiology Research Associate
- 2008/04 - 2010/03 Otaru Municipal Hospital Dept. of Anesthesia Chief Anesthesiologist
- 2004/10 - 2008/03 Sapporo Medical University Dept. of Anesthesiology Postgraduate Student
- 2003/04 - 2004/09 Nikko Memorial Hospital Dept. of Anesthesia Staff Anesthesiologist
- 2002/04 - 2003/03 Sapporo Medical University Dept. of Anesthesiology Staff Anesthesiologist
- 2001/04 - 2002/03 Kitami Red Cross Hospital Dept. of Anesthesia Staff Anesthesiologist
- 2000/04 - 2001/03 Kushiro City General Hospital Dept. of Anesthesia Staff Anesthesiologist
- 1999/03 - 2000/02 Asahikawa City Hospital Dept. of Anesthesia Resident
- 1998/04 - 1999/03 Sapporo Medical University Dept. of Anesthesiology Resident
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Awards (4):
- 2024/04 - The 11th Annual Meeting of Japanese Regional Anesthesia Society Good Presentation Award Pulsed radio-frequency with peripheral nerve block attenuates postoperative pain via Fyn tyrosine kinase expression.
- 2019/09 - JSA Hokkaido-Tohoku Branch 9th Annual Meeting Best Presentation Award Effect of Dexmedetomidine on A Rat Model of Postoperative Nausea and Vomiting
- 2005/05 - The 58th Annual Meeting of Hokkaido Anesthesia Society (JSA Hokkaido-Tohoku Branch) Best Presentation Award Strain differences in excitability of mouse RVM neuron in response to intracerebroventricular administration of DAMGO
- 2005/03 - Japanese Society for Abdominal Emergency Medicine Best Research Award Transcatheter Arterial Embolization of Blunt Abdominal Trauma Patients in Remote Medical Area: A Case Series
Association Membership(s) (7):
AMERICAN SOCIETY OF HUMAN GENETICS
, AMERICAN SOCIETY OF ANESTHESIOLOGISTS
, SOCIETY FOR NEUROSCIENCE
, THE JAPANESE SOCIETY OF INTENSIVE CARE MEDICINE
, JAPANESE SOCIETY OF ANESTHESIOLOGISTS
, Japan Society for Clinical Anesthesia
, European Society of Anaesthesiolgy and Intensive Care
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