Rchr
J-GLOBAL ID:201601019523177903   Update date: Oct. 23, 2024

Takayama Naoya

Takayama Naoya | Takayama Naoya
Affiliation and department:
Research field  (1): Cell biology
Research theme for competitive and other funds  (6):
  • 2022 - 2027 骨癒合促進特化型ユニバーサルiPS血小板製剤の開発
  • 2020 - 2023 Study for the regulation of exit from quiescent self-renewing programs in human hematopoietic stem cells by chromatin looping factor, CTCF
  • 2019 - 2022 Development of iPS cell-derived platelet preparation with bone fusion promoting effect
  • 2017 - 2020 Study for self-renewal in human hematopoietic stem cells by genome wide epigenetic analysis
  • 2011 - 2012 CAMT-iPS Cells Exhibiting Defective MPL Signaling Dysregulate hematopoiesis
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Papers (83):
  • Kentaro Kosaka, Naoya Takayama, Sudip Kumar Paul, Maria Alejandra Kanashiro, Motohiko Oshima, Masaki Fukuyo, Bahityar Rahmutulla, Ikuko Tajiri, Michiaki Mukai, Yoshitaka Kubota, et al. iPSC-derived megakaryocytes and platelets accelerate wound healing and angiogenesis. Stem Cell Research & Therapy. 2024. 15. 1
  • Sudip Kumar Paul, Motohiko Oshima, Ashwini Patil, Masamitsu Sone, Hisaya Kato, Yoshiro Maezawa, Hiyori Kaneko, Masaki Fukuyo, Bahityar Rahmutulla, Yasuo Ouchi, et al. Retrotransposons in Werner syndrome-derived macrophages trigger type I interferon-dependent inflammation in an atherosclerosis model. Nature communications. 2024. 15. 1. 4772-4772
  • Takahito Arai, Yasuhiro Shiga, Michiaki Mukai, Naoya Takayama, Susumu Tashiro, Ikuko Tajiri, Kentaro Kosaka, Masashi Sato, Sou Nakamura, Haruki Okamoto, et al. Osteogenic effects and safety of human induced pluripotent stem cell-derived megakaryocytes and platelets produced on a clinical scale. Regenerative therapy. 2024. 26. 850-858
  • Si Jing Chen, Kazuya Hashimoto, Kosuke Fujio, Karin Hayashi, Sudip Kumar Paul, Akinori Yuzuriha, Wei-Yin Qiu, Emiri Nakamura, Maria Alejandra Kanashiro, Mio Kabata, et al. A let-7 microRNA-RALB axis links the immune properties of iPSC-derived megakaryocytes with platelet producibility. Nature Communications. 2024. 15. 1
  • 向井 務晃, 志賀 康浩, 江口 和, 水木 誉凡, 小坂 健太朗, 稲毛 一秀, 折田 純久, 高山 直也, 江藤 浩之, 大鳥 精司. ヒトiPS細胞由来巨核球・血小板製剤とBMP-2の骨再生能と安全性についての検討. 移植. 2023. 58. 3. 294-294
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MISC (36):
  • 大島 基彦, 高山 直也, 中島 やえ子, 小出 周平, 原田 浩徳, 原田 結花, Ding Ye, 明星 智洋, 岩間 厚志. MDS幹・前駆細胞の分子病態解析(Molecular pathogenesis in MDS stem and progenitor cells). 日本血液学会学術集会. 2021. 83回. OS1-1
  • 佐藤 雅, 志賀 康浩, 高山 直也, 小坂 健太朗, 水木 誉凡, 向井 務晃, 折田 純久, 江藤 浩之, 大鳥 精司. ヒト人工多能性幹細胞由来巨核球/血小板の骨形成促進効果に関する検討. 日本整形外科学会雑誌. 2021. 95. 8. S1576-S1576
  • 上田 玲央斗, 志賀 康浩, 笠井 凌平, 高山 直也, 佐藤 雅, 水木 誉凡, 向井 務晃, 小坂 健太朗, 江藤 浩之, 大鳥 精司, et al. ヒト多血小板血漿とヒト細胞由来の人工多能性幹細胞由来血小板の成長因子定量比較. 日本整形外科学会雑誌. 2021. 95. 8. S1577-S1577
  • PAUL Sudip K., SONE Masamitsu, KATO Hisaya, MAEZAWA Yoshiro, OSHIMA Motohiko, OUCHI Yasuo, IWAMA Atsushi, YOKOTE Koutaro, ETO Koji, ETO Koji, et al. Interferon signaling in macrophage derived from Werner syndrome-iPSCs promotes aberrant inflammation. 日本血液学会学術集会抄録(Web). 2021. 83rd
  • 高石 浩司, 武内 正博, 塚本 祥吉, 高山 直也, 大島 基彦, 中村 壮, 江藤 浩之, 岩間 厚志, 横手 幸太郎, 中世古 知昭, et al. iPS細胞由来巨核球系前駆細胞株を用いたアナグレリドによる血小板産生抑制機構の解明. 日本臨床分子医学会学術総会プログラム・抄録集. 2019. 56回. 53-53
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