Research theme for competitive and other funds (3)：
2022 - 2025 人工知能を有する自動回折データ収集システムの開発
2012 - 2015 Bioactive substances from marine cyanobacteria
2007 - 2008 Molecular analysis of sperm-egg fusion as a model system of cell-cell fusion
Papers (147)：
Mariko Kojima, Satoshi Abe, Tadaomi Furuta, Kunio Hirata, Xinchen Yao, Ayako Kobayashi, Ririko Kobayashi, Takafumi Ueno. High-throughput structure determination of an intrinsically disordered protein using cell-free protein crystallization. Proceedings of the National Academy of Sciences. 2024. 121. 25
Hye-Eun Lee, Tomoyo Okumura, Hideshi Ooka, Kiyohiro Adachi, Takaaki Hikima, Kunio Hirata, Yoshiaki Kawano, Hiroaki Matsuura, Masaki Yamamoto, Masahiro Yamamoto, et al. Osmotic Energy Conversion in Deep-Sea Hydrothermal Vents. 2023
Xinyu Xu, Jeremy Shonberg, Jonas Kaindl, Mary J. Clark, Anne Stößel, Luis Maul, Daniel Mayer, Harald Hübner, Kunio Hirata, A. J. Venkatakrishnan, et al. Constrained catecholamines gain β2AR selectivity through allosteric effects on pocket dynamics. Nature Communications. 2023
Mariko Kojima, Satoshi Abe, Tadaomi Furuta, Duy Phuoc Tran, Kunio Hirata, Keitaro Yamashita, Yuki Hishikawa, Akio Kitao, Takafumi Ueno. Engineering of an in-cell protein crystal for fastening a metastable conformation of a target miniprotein. Biomaterials Science. 2023
Nozomi Sugano-Nakamura, Kyoko Matoba, Mika Hirose, Nasir K Bashiruddin, Yukiko Matsunaga, Keitaro Yamashita, Kunio Hirata, Masaki Yamamoto, Takao Arimori, Hiroaki Suga, et al. De novo Fc-based receptor dimerizers differentially modulate PlexinB1 function. Structure (London, England : 1993). 2022. 30. 10. 1411-1423
Reo Takeda, Masatoshi Maeki, Sho Ito, Go Ueno, Kunio Hirata, Akihiko Ishida, Hirofumi Tani, Masaki Yamamoto, Manabu Tokeshi. HIGH-THROUGHPUT X-RAY CRYSTALLOGRAPHY BASED ON THE PROTEIN CRYASTAL ARRAY. Proc. Micro TAS 2019. 2019. 191-192
Raw diffraction images of plant vacuolar iron transporter VIT1 (with Zn and Co). Zenodo. 2019
Current status of automatic data collection by ZOO at SPring-8
(Current and Future Trends in Macromolecular Crystallography Experiments: Focus on Automation, High Data Rate Analysis and User Interfaces 2021)
協働ロボットを利用した高速結晶凍結システムの開発
(日本放射光学会年会 2021)
SPring-8におけるタンパク質結晶自動凍結装置の開発
(日本結晶学会年会 2020)
Effects of dose control in multiple small wedge data collection
(Radiation Damage on Biological sample 11th conferentce 2020)
High resolution data collection with Protein micro crystals
(The CCP4/Shanghai School in Macromolecular Crystallography: From Data Collection to Structure Refinement 2019)
2019/11 - The Crystallographic Society of Japan Academic Award Research and development of the Rapid automatic data collection system for protein micro-crystallography
