Ngo Kien Xuan

• 2023 - 2026 Grants-in-Aid for Scientific Research (JSPS) (type B 23H02452-01) The mechanism of sparsely coupled actin-binding proteins regulate the function of the entire actin filament.
• 2023 - 2026 Grants-in-Aid for Scientific Research (JSPS) (type C-23K05713)-Structures and dynamics of ABC transporters MsbA and LptB2FG in working with LptC during transport activities
• 2024 - 2025 Deciphering A Novel Gate Operation Pathway of Lipopolysaccharide Transport by Bacterial ABC Transporters MsbA and LptC through A Multidimensional Approach
• 2022 - 2025 BIO-SPM Research Collaborative Fund FY2022- Pore formation of alpha-toxin from Staphylococcus aureus and its toxoids investigated by Atomic Force Microscopy
• 2018 - 2025 Kanazawa University Fund [Strategic Research Promotion Program (Core-to-Core Program)]
2022 - 2023 WPI NanoLSI TDRP - Temperature-modulated supramolecular nanomachinery for manipulating programmed cell death
2022 - 2023 Temperature-modulated supramolecular nanomachinery for manipulating programmed cell death
2019 - 2022 Grants-in-Aid for Scientific Research (JSPS) (type C)-Project No. 19K06581
2020 - 2021 WPI-NanoLSI Transdisciplinary Research Promotion Grant
2019 - 2020 BIO-SPM Research Collaborative Fund FY2019
2019 - 2020 WPI-NanoLSI Transdisciplinary Research Promotion Grant
2018 - 2019 BIO-SPM Research Collaborative Fund FY2018
2018 - 2019 WPI-NanoLSI Transdisciplinary Research Promotion Grant
2018 - 2019 WPI-NanoLSI Startup
2012 - 2017 Actin structural polymorphism machinery that orchestrates amoeba motility
2012 - 2017 Japan Society for the Promotion of Science Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)

• Hidenori Homma, Kien Xuan Ngo, Yuki Yoshioka, Hikari Tanaka, Maiko Inotsume, Kyota Fujita, Toshio Ando, Hitoshi Okazawa. PQBP3/NOL7 is an intrinsically disordered protein. Biochemical and Biophysical Research Communications. 2024
• Yuki Yoshioka, Yong Huang, Xiaocen Jin, Kien Xuan Ngo, Tomohiro Kumaki, Meihua Jin, Saori Toyoda, Sumire Takayama, Maiko Inotsume, Kyota Fujita, et al. PQBP3 prevents senescence by suppressing PSME3-mediated proteasomal Lamin B1 degradation. The EMBO Journal. 2024
• Kien Xuan Ngo, Huong T Vu, Kenichi Umeda, Minh-Nhat Trinh, Noriyuki Kodera, Taro Uyeda. Deciphering the actin structure-dependent preferential cooperative binding of cofilin. eLife. 2024. 13
• Kien Xuan Ngo, Huong T Vu, Kenichi Umeda, Minh-Nhat Trinh, Noriyuki Kodera, Taro QP Uyeda. The functions of actin-binding proteins are regulated by the flexibility and specific helical twists of actin filaments. EUREKALERT AAAS. 2024
• Toshio Ando, Shingo Fukuda, Kien X. Ngo, Holger Flechsig. High-Speed Atomic Force Microscopy for Filming Protein Molecules in Dynamic Action. Annual Review of Biophysics. 2024. 53. 1. 19-39

ｍore...

• Uni-directional Propagation of Structural Changes in Actin Filaments.” The Role of Water in ATP Hydrolysis Energy Transduction by Protein Machinery
  Springe Nature Singapore 2018

• The oligomerization and neutralization capabilities of alpha-hemolysin (Hla) toxin from Staphylococcus aureus by mutant Hla proteins
  (Rencontres du Vietnam: The second International Symposium of Nano Life Science: Nano Biotechnology, Biophysics, Computation (NanoBioCoM2024) 2024)
• A Novel Gate Operating Pathway of Lipopolysaccharide Transport by Bacterial ABC Transporter MsbA and LptC
  (Rencontres du Vietnam: The second International Symposium of Nano Life Science: Nano Biotechnology, Biophysics, Computation (NanoBioCoM2024) 2024)
• An Innovative Approach for Watching Dynamic Conformational Changes in Proteins at Ultrafast and Atomistic Levels
  (Materials Informatics: Accelerating Materials Research and Design with Artificial Intelligence 2024)
• S100A11 promotes focal adhesion disassembly via myosin IIdriven contractility and Piezo1-mediated Ca2+ entry
  (IUPAB2024 - 21st IUPAB and 62nd BSJ Joint Congress 2024 2024)
• A Novel Gate Operation Pathway of Lipopolysaccharide Transport by Bacterial ABC Transporter MsbA and LptC
  (IUPAB2024 - 21st IUPAB and 62nd BSJ Joint Congress 2024 2024)

ｍore...

• 2005 - 2009 Osaka University, Japan Chemical Engineering Science PhD
• 2003 - 2005 Osaka University, Japan Chemical Engineering Science Master
• 1996 - 2000 Vietnam National University of Agriculture (VNUA) Food Science and Technology Bachelor

• PhD (Grad. Eng. Sci., Osaka University)

• 2018/04 - 現在 Kanazawa University, Japan Nano Life Science Institute (WPI-NanoLSI) Assistant Professor
• 2017/04 - 2018/03 RIKEN, Japan Brain Science Institute Research Scientist
• 2016/04 - 2017/03 Waseda University, Japan Department of Physics, Faculty of Science and Engineering Senior Researcher
• 2013/05 - 2016/03 National Institute of Advanced Industrial Science and Technology (AIST) Biomedical Research Institute, Cell Mechanics Research Group Postdoctoral Special Researcher
• 2011/07 - 2013/04 University of Geneva, Switzerland Faculty of Sciences, Department of Inorganic and Analytical Chemistry Postdoctoral Research Assistant
2009/11 - 2011/06 National Institute of Advanced Industrial Science and Technology (AIST) Biomedical Research Institute, Cell Mechanics Research Group Postdoctoral Special Researcher
2006/04 - 2009/03 Graduate School of Engineering Science, Osaka University JSPS Fellowship (DC1) Doctoral Students
2001/01 - 2003/09 Vietnam Institute of Post Harvest Technology, Hanoi, Vietnam. Department of Microbiology Junior Researcher

• 2024/12 - ICISE center Co-chaiman - Vietnam Workshop on Microscopy 2024 Co-chairman
• 2024/09 - Co-Chairman - The Second International Symposium of Nano Life Science (NanoBioCoM 2024)
• 2024/08 - Rencontres du Vietnam Co-Organizers - Materials Informatics: Accelerating Materials Research and Design with Artificial Intelligence
• 2024/06 - The Vietnamese Biophysical Society (VBS) A representative for the Vietnamese Biophysical Society (VBS) to attend the IUPAB Assembly Congress in Kyoto IUPAB in June 2024 VBS becomes an adhering Body of IUPAB
• 2023/09 - Travel Award WPI Nano Life Science Institute, Kanazawa University Travel Award to organize and attend NanoBioCoM2023
2023/09 - Co-Chairmans - The First International Symposium of Nano Life Science (NanoBioCoM2023)
2023/06 - Frontiers Member of Frontiers Reviewer Committee
2022/07 - American Phytopathology Society (APS) Editor's Pick from July Issue of Phytopathology Unraveling the host-selective toxic interaction of cassiicolin with lipid membranes and its cytotoxicity
2021/02 - RIKEN RIKEN Press Elucidation of the molecular mechanism by which microtubules are produced - Only a few linear oligomers become microtubules
2016/11 - F1000Prime, Faculty of 1000 Ltd, Science Navigation Group F1000Prime Allosteric regulation by cooperative conformational changes of actin filaments drives mutually exclusive binding with cofilin and myosin
2015/02 - F1000Prime, Faculty of 1000 Ltd, Science Navigation Group F1000Prime Cofilin-induced unidirectional cooperative conformational changes in actin filaments revealed by high-speed atomic force microscopy
2010/11 - F1000Prime, Faculty of 1000 Ltd, Science Navigation Group F1000Prime Structural basis for actin assembly, activation of ATP hydrolysis, and delayed phosphate release.
2006/04 - Grant in Aid for Scientific Research (JSPS), Japan JSPS Fellowship DC1
2003/10 - Vietnamese Government A fully qualified scholarship from Vietnamese Government for studying oversea

The Vietnamese Biophysical Society (VBS) ,  American Phytopathological Society (APS) ,  Swiss Laboratory Animal Science Association ,  Swiss Soft Days Organization ,  Swiss Chemical Society ,  American Biophysical Society ,  The Biophysical Society of Japan (BSJ) ,  The Society for Chemical Engineers, Japan (SCEJ) ,  The Society of Separation Process Engineers, Japan (SSPEJ) ,  The Society for Biotechnology, Japan (SBJ)