Art

J-GLOBAL ID：201602201377880326   Reference number：16A0258687

Cefpodoxime Concentrations in Human Serum and Oral Tissues Following a Single Oral Administration of Cefpodoxime Proxetil

セフポドキシムプロキセチルの単回経口投与後のヒト血清および口内組織中のセフポドキシム濃度

Author (13)： ONO Makiko (Departments of Oral Surgery, Nihon Univ. School of Dentistry at Matsudo, Matsudo, Chiba, 271-8587, JPN) ,  ONO Makiko (Resarch Inst. of Oral Sci., Nihon Univ. School of Dentistry at Matsudo, Matsudo, Chiba, 271-8587, JPN) ,  OMATA Hiroaki (Departments of Oral Surgery, Nihon Univ. School of Dentistry at Matsudo, Matsudo, Chiba, 271-8587, JPN) ,  NISHIMURA Hitoshi (Departments of Oral Surgery, Nihon Univ. School of Dentistry at Matsudo, Matsudo, Chiba, 271-8587, JPN) ,  NISHIMURA Hitoshi (Resarch Inst. of Oral Sci., Nihon Univ. School of Dentistry at Matsudo, Matsudo, Chiba, 271-8587, JPN) ,  TANAKA Shigeo (Departments of Oral Surgery, Nihon Univ. School of Dentistry at Matsudo, Matsudo, Chiba, 271-8587, JPN) ,  TANAKA Shigeo (Resarch Inst. of Oral Sci., Nihon Univ. School of Dentistry at Matsudo, Matsudo, Chiba, 271-8587, JPN) ,  MATSUMOTO Hiroko (Resarch Inst. of Oral Sci., Nihon Univ. School of Dentistry at Matsudo, Matsudo, Chiba, 271-8587, JPN) ,  MATSUMOTO Hiroko (Departments of Pharmacology, Nihon Univ. School of Dentistry at Matsudo, Matsudo, Chiba, 271-8587, JPN) ,  FUJII Akira (Professor Emeritus, Nihon Univ., 4-8-24 Kudan-Minami, Chiyoda, Tokyo 102-8275, JPN) ,  AKIMOTO Yoshiaki (Departments of Oral Surgery, Nihon Univ. School of Dentistry at Matsudo, Matsudo, Chiba, 271-8587, JPN) ,  KOMIYA Masamichi (Departments of Oral Surgery, Nihon Univ. School of Dentistry at Matsudo, Matsudo, Chiba, 271-8587, JPN) ,  KOMIYA Masamichi (Resarch Inst. of Oral Sci., Nihon Univ. School of Dentistry at Matsudo, Matsudo, Chiba, 271-8587, JPN)
Material： International Journal of Oral-Medical Sciences  (IJOMS)
Volume： 14  Issue： 2-3  Page： 48-53 (J-STAGE)  Publication year： 2016 
JST Material Number： L4836A  ISSN： 1347-9733  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *cephalosporins ,...
Semi thesaurus term： Odontogenic infection

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JST classification (2)： Clinical biopharmacy  (GY01022L) ,  Clinical dentistry(= odontology)in general  (GT01030Z)

Substance index (1)： Cefpodoxime proxetil

Reference (20)：

• 1. Jones RN, Barry AL: Antimicrobial activity and disk diffusion susceptibility testing of U-76,253A(R-3746), the active metabolite of the new cephalosporin ester, U-76,252(CS-807). Antimicrob Agents Chemother, 32: 443-449, 1988.
• 2. Komai T, Kawai K, Tsubake H, Tokui T, Kinoshita T, Tanaka M: Absorption, distribution, metabolism, and excretion of CS-807, a new oral cephem antibiotic, in experimental animals. Chemotherapy(Tokyo), 36(Suppl. 1): 229-240, 1988.
• 3. Yokota T, Suzuki E, Arai K: Cefpodoxime proxetil, its in vitro antibacterial activity, affinity to bacterial penicillin-binding proteins, and synergy of bactericidal activity with serum complement and mouse-cultured macrophages. Drugs Exp Clin Res, 14: 495-500, 1988.
• 4. Fass RJ, Helsel VL: In vitro activity of U-76,252(CS-807), a new oral cephalosporin. Antimicrob Agents Chemother, 32: 1082-1085, 1988.
• 5. Jones RN, Barry AL, Pfaller M, Allen SD, Iyers LW, Fuchs PC: Antimicrobial activity of U-76,252(CS-807), a new orally administered cephalosporin ester, including recommendations for MIC quality control. Diagn Microbiol Infect Dis, 9: 59-63, 1988.

Terms in the title (5)： セフポドキシムプロキセチル ,  経口投与 ,  ヒト血清 ,  組織 ,  セフポドキシム