Art

J-GLOBAL ID：201602202467214046   Reference number：16A0252204

Inhibition of Melanin Synthesis and Skin Whitening Effect by Heat-induced Yeast Extract (Cerepron)

熱水処理による酵母エキス(セレプロン)によるメラニン合成抑制及び皮膚ホワイトニング作用

Author (7)： IINO Takashi (Pharma Foods International Co., Ltd.) ,  SAKASHITA Maya (Pharma Foods International Co., Ltd.) ,  YAMASHITA Yusuke (Pharma Foods International Co., Ltd.) ,  HARADA Seiyu (Pharma Foods International Co., Ltd.) ,  KIM Jeong-Won (Pharma Foods International Co., Ltd.) ,  KOSAKA Hisayuki (Osaka Hospital, Osaka, JPN) ,  KIM Mujo (Pharma Foods International Co., Ltd.)
Material： 薬理と治療  (日本臨床試験学会雑誌)
Volume： 44  Issue： 2  Page： 221-226  Publication year： Feb. 20, 2016 
JST Material Number： Z0947A  ISSN： 0386-3603  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *yeast extract ,...
Semi thesaurus term： *セレプロン ,...

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JST classification (3)： Basic dermatology  (GF01020Y) ,  Clinical dermatology in general  (GF01030J) ,  Food in general  (FJ01010Y)

Reference (13)：

• Chung SY, Seo YK, Park JM, Seo MJ, Park JK, Kim JW, et al. Fermented rice bran downregulates MITF expression and leads to inhibition of α-MSH-induced melanogenesis in B16F1 melanoma. Biosci Biotech Biochem 2009; 73: 1704-10.
• Costin GE, Hearing VJ. Human skin pigmentation: melanocytes modulate skin color in response to stress. FASEB J 2007; 21: 976-94.
• Gillbro JM, Olsson MJ. The melanogenesis and mechanisms of skin-lightening agents-existing and new approaches. Internat J Cosmetic Sci 2011; 33: 210-21.
• Kinoshita M, Hori N, Aida K, Sugawara T, Ohnishi M. Prevention of melanin formation by yeast cerebroside in B16 mouse melanoma cells. J Oleo Sci 2007; 56: 645-8.
• Lee WJ, Rhee DY, Bang SH, Kim SY, Won CH, Lee MW, et al. The natural yeast extract isolated by ethanol precipitation inhibits melanin synthesis by modulating tyrosinase activity and downregulating melanosome transfer. Biosci Biotech Biochem 2015; 79: 1504-11.

Terms in the title (4)： 熱水処理 ,  酵母エキス ,  メラニン ,  皮膚