Art

J-GLOBAL ID：201602207959116769   Reference number：16A0119087

Chimeric RNA Oligonucleotides with Triazole and Phosphate Linkages: Synthesis and RNA Interference

トリアゾールとリン酸連結を持つキメラ状RNAオリゴヌクレオチド:合成とRNA干渉

Author (8)： FUJINO Tomoko (Dep. of Chemistry, Tohoku Univ., Aoba-ku, Sendai, 980-8578, JPN) ,  KOGASHI Kanako (Dep. of Chemistry, Tohoku Univ., Aoba-ku, Sendai, 980-8578, JPN) ,  OKADA Koudai (Dep. of Chemistry, Tohoku Univ., Aoba-ku, Sendai, 980-8578, JPN) ,  MATTARELLA Martin (Dep. of Chemistry, Tohoku Univ., Aoba-ku, Sendai, 980-8578, JPN) ,  SUZUKI Takeru (Dep. of Chemistry, Tohoku Univ., Aoba-ku, Sendai, 980-8578, JPN) ,  YASUMOTO Kenichi (Dep. of Biomolecular Sciences, Tohoku Univ., Aoba-ku, Sendai, 980-8578, JPN) ,  SOGAWA Kazuhiro (Dep. of Biomolecular Sciences, Tohoku Univ., Aoba-ku, Sendai, 980-8578, JPN) ,  ISOBE Hiroyuki
Material： Chemistry. Asian Journal  (Chem Asian J)
Volume： 10  Issue： 12  Page： 2683-2688  Publication year： Dec. 2015 
JST Material Number： W1856A  ISSN： 1861-4728  CODEN： CAAJBI  Document type： Article
Article type： 原著論文  Country of issue： Germany, Federal Republic of (DEU)  Language： ENGLISH (EN)

Thesaurus term： *Chimera ,  *oligonucleotide ,  *RNA interference ,  *nucleotide analog ,  nitrogen heterocyclic compound ,  siRNA ,  *cycloaddition ,  *inorganic acid ester ,  chemical synthesis ,  molecular structure ,  nucleotide sequence ,  gene expression ,  *chromoprotein ,  *phosphoramidite ,  Huisgen reaction ,  Triazoles ,  Phosphoric Acid Esters ,  Yellow Fluorescent Protein ,  *Heredity ,  molecular genetic phenomenon
Semi thesaurus term： Huisgen cycloaddition reaction ,  oligonucleotides ,  Triazoles ,  Phosphoric Acid Esters ,  yellow fluorescent protein ,  nucleotide sequence

JST classification (3)： Nucleosides,nucleotides  (CF10060K) ,  Triazoles  (CF07084O) ,  Biological function  (EB04020F)

Substance index (3)： 5′-[1-[1-(Uracil-1-yl)-2-O-acetyl-5-O-(4,4′-dimethyltrityl)-1,3-dideoxy-β-D-ribofuranose-3-yl]-1H-1,2,3-triazole-4-yl]-2′-O-(tert-butyldimethylsilyl)-3′-O-[2-cyanoethoxy(diisopropylamino)phosphino]-5′-deoxyuridine ,  5′-[1-[1-(N-Benzoylcytosine-1-yl)-2-O-acetyl-5-O-(4,4′-dimethyltrityl)-1,3-dideoxy-β-D-ribofuranose-3-yl]-1H-1,2,3-triazole-4-yl]-2′-O-(tert-butyldimethylsilyl)-3′-O-[2-cyanoethoxy(diisopropylamino)phosphino]-5′-deoxyuridine ,  5′-[1-[1-(N-Benzoylcytosine-1-yl)-2-O-acetyl-5-O-(4,4′-dimethyltrityl)-1,3-dideoxy-β-D-ribofuranose-3-yl]-1H-1,2,3-triazole-4-yl]-2′-O-(tert-butyldimethylsilyl)-3′-O-[2-cyanoethoxy(diisopropylamino)phosphino]-N-benzoyl-5′-deoxycytidine

Terms in the title (6)： トリアゾール ,  リン酸 ,  キメラ ,  RNA ,  オリゴヌクレオチド ,  RNA干渉