Art

J-GLOBAL ID：201602210407434953   Reference number：16A0003801

Pioglitazone Reduces Vascular Lipid Accumulation in Angiotensin II-Induced Hypertensive Rat

ピオグリタゾンはアンジオテンシンII誘発性高血圧ラットにおける血管脂質蓄積を減弱させる

Author (10)： SAKAMOTO Aiko (Dep. of Cardiovascular Medicine, Univ. of Tokyo Graduate School of Medicine) ,  HIGASHIKUNI Yasutomi (Dep. of Cardiovascular Medicine, Univ. of Tokyo Graduate School of Medicine) ,  HONGO Makiko (Dep. of Cardiovascular Medicine, Univ. of Tokyo Graduate School of Medicine) ,  IMAI Yasushi (Dep. of Cardiovascular Medicine, Univ. of Tokyo Graduate School of Medicine) ,  IMAI Yasushi (Dep. of Cardiovascular Medicine, Jichi Medical Univ.) ,  KOIKE Kazuhiko (Dep. of Gastroenterology, Univ. of Tokyo Graduate School of Medicine) ,  NAGAI Ryozo (Dep. of Cardiovascular Medicine, Univ. of Tokyo Graduate School of Medicine) ,  NAGAI Ryozo (Jichi Medical Univ.) ,  KOMURO Issei (Dep. of Cardiovascular Medicine, Univ. of Tokyo Graduate School of Medicine) ,  ISHIZAKA Nobukazu (Div. of Cardiology, Osaka Medical Coll.)
Material： Journal of Atherosclerosis and Thrombosis (Web)  (J Atheroscler Thromb (Web))
Volume： 22  Issue： 12  Page： 1225-1234 (J-STAGE)  Publication year： 2015 
JST Material Number： U0153A  ISSN： 1880-3873  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： rat ,...
Semi thesaurus term： Nox1 ,...

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JST classification (2)： Basic medicine on cardiovascular system  (GJ01020K) ,  Basic research of vasoactive drugs and hypotensive drugs  (GW07040J)

Substance index (1)： Pioglitazone

Reference (41)：

• 1) Isa SA, Ruffino JS, Ahluwalia M, Thomas AW, Morris K, Webb R: M2 macrophages exhibit higher sensitivity to oxLDL-induced lipotoxicity than other monocyte/macrophage subtypes. Lipids Health Dis, 2011; 10: 229
• 2) Despres JP, Lemieux I: Abdominal obesity and metabolic syndrome. Nature, 2006; 444: 881-887
• 3) Fox CS, Massaro JM, Hoffmann U, Pou KM, Maurovich-Horvat P, Liu CY, Vasan RS, Murabito JM, Meigs JB, Cupples LA, D'Agostino RB, Sr., O'Donnell CJ: Abdominal visceral and subcutaneous adipose tissue compartments: association with metabolic risk factors in the Framingham Heart Study. Circulation, 2007; 116: 39-48
• 4) Lim S, and Meigs JB: Ectopic fat and cardiometabolic and vascular risk. Int J Cardiol, 2013; 169: 166-176
• 5) Wende AR, Symons JD, Abel ED: Mechanisms of lipotoxicity in the cardiovascular system. Curr Hypertens Rep, 2012; 14: 517-531

Terms in the title (6)： ピオグリタゾン ,  アンジオテンシンII ,  高血圧ラット ,  血管 ,  脂質蓄積 ,  減弱