Art

J-GLOBAL ID：201602210928390421   Reference number：16A0215009

Serum Autotaxin Levels Are Associated with Proteinuria and Kidney Lesions in Japanese Type 2 Diabetic Patients with Biopsy-proven Diabetic Nephropathy

血清オートタキシンレベルは生検証明糖尿病性腎症を伴う日本人2型糖尿病患者における腎臓病変と関連する

Author (16)： SHIMIZU Miho (Div. of Nephrology, Kanazawa Univ. Hospital, JPN) ,  SHIMIZU Miho (Dep. of Disease Control and Homeostasis, Kanazawa Univ. Graduate School of Medical Sciences, JPN) ,  FURUICHI Kengo (Div. of Nephrology, Kanazawa Univ. Hospital, JPN) ,  FURUICHI Kengo (Dep. of Disease Control and Homeostasis, Kanazawa Univ. Graduate School of Medical Sciences, JPN) ,  TOYAMA Tadashi (Div. of Nephrology, Kanazawa Univ. Hospital, JPN) ,  TOYAMA Tadashi (Dep. of Disease Control and Homeostasis, Kanazawa Univ. Graduate School of Medical Sciences, JPN) ,  YAMAHANA Junya (Dep. of Disease Control and Homeostasis, Kanazawa Univ. Graduate School of Medical Sciences, JPN) ,  YAMAHANA Junya (Dep. of Internal Medicine, Toyama Prefectural Central Hospital, JPN) ,  OHKAWA Ryunosuke (Dep. of Clinical Lab., The Univ. of Tokyo Hospital, JPN) ,  IGARASHI Koji (Bioscience Div., Reagent Dev. Dep., AIA Res. Group, TOSOH Corp., JPN) ,  AOKI Junken (Lab. of Molecular and Cellular Biochemistry, Graduate School of Pharmaceutical Sciences, Tohoku Univ., JPN) ,  KANEKO Shuichi (Dep. of Disease Control and Homeostasis, Kanazawa Univ. Graduate School of Medical Sciences, JPN) ,  YATOMI Yutaka (Dep. of Clinical Lab., The Univ. of Tokyo Hospital, JPN) ,  YATOMI Yutaka (Dep. of Clinical Lab. Medicine, Graduate School of Medicine, The Univ. of Tokyo, JPN) ,  WADA Takashi (Div. of Nephrology, Kanazawa Univ. Hospital, JPN) ,  WADA Takashi (Dep. of Lab. Medicine, Kanazawa Univ. Graduate School of Medical Sciences, JPN)
Material： Internal Medicine (Web)  (Intern Med (Web))
Volume： 55  Issue： 3  Page： 215-221 (J-STAGE)  Publication year： 2016 
JST Material Number： U0033A  ISSN： 1349-7235  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： human(primates) ,...
Semi thesaurus term： *type 2 diabetic nephropathy ,...

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JST classification (2)： Metabolic diseases,nutritional diseases in general.  (GD05010J) ,  Urogenital diseases  (GM03000L)

Reference (50)：

• 1. American Diabetes Association. Standards of medical care in diabetes-2015. Diabetes Care 38: S58-S66, 2015.
• 2. Wada T, Haneda M, Furuichi K, et al; Research Group of Diabetic Nephropathy, Ministry of Health, Labour, and Welfare of Japan. Clinical impact of albuminuria and glomerular filtration rate on renal and cardiovascular events, and all-cause mortality in Japanese patients with type 2 diabetes. Clin Exp Nephrol 18: 613-620, 2014.
• 3. Shimizu M, Furuichi K, Toyama T, et al; Kanazawa Study Group for Renal Diseases and Hypertension. Long-term outcomes of Japanese type 2 diabetic patients with biopsy-proven diabetic nephropathy. Diabetes Care 36: 3655-3662, 2013.
• 4. Shimizu M, Furuichi K, Yokoyama H, et al. Kidney lesions in diabetic patients with normoalbuminuric renal insufficiency. Clin Exp Nephrol 18: 305-312, 2014.
• 5. Umezu-Goto M, Kishi Y, Taira A, et al. Autotaxin has lysophospholipase D activity leading to tumor cell growth and motility by lysophosphatidic acid production. J Cell Biol 158: 227-233, 2002.

Terms in the title (10)： 血清 ,  オートタキシン ,  生検 ,  証明 ,  糖尿病性腎症 ,  日本人 ,  2型糖尿病 ,  患者 ,  腎臓 ,  病変