Art

J-GLOBAL ID：201602211511903047   Reference number：16A0721336

Dynamic Kinetic Resolution Approach for the Asymmetric Synthesis of Tetrahydrobenzodiazepines Using Transfer Hydrogenation by Chiral Phosphoric Acid

キラルリン酸による移動水素化を用いたテトラヒドロベンゾジアゼピン類の不斉合成のための動的速度論的分割アプローチ

Author (6)： Horiguchi Kosaku (Department of Chemistry, Gakushuin University, 1-5-1 Mejiro, Toshima-ku, Tokyo, 171-8588, Japan) ,  Yamamoto Eri (Department of Chemistry, Rikkyo University, 3-34-1 Nishi-Ikebukuro, Toshima-ku, Tokyo, 171-8501, Japan) ,  Saito Kodai (Department of Chemistry, Gakushuin University, 1-5-1 Mejiro, Toshima-ku, Tokyo, 171-8588, Japan) ,  Saito Kodai (Department of Chemistry, Keio University, Hiyoshi, Kohoku-ku, Yokohama, Kanagawa, 223-8522, Japan) ,  Yamanaka Masahiro (Department of Chemistry, Rikkyo University, 3-34-1 Nishi-Ikebukuro, Toshima-ku, Tokyo, 171-8501, Japan) ,  Akiyama Takahiko (Department of Chemistry, Gakushuin University, 1-5-1 Mejiro, Toshima-ku, Tokyo, 171-8588, Japan. [e-mail])
Material： Chemistry - European Journal  (Chem Eur J)
Volume： 22  Issue： 24  Page： 8078-8083  Publication year： 2016 
JST Material Number： W0744A  ISSN： 0947-6539  CODEN： CEUJED  Document type： Article
Article type： 短報  Country of issue： Germany, Federal Republic of (DEU)  Language： ENGLISH (EN)

Thesaurus term： *optical resolution ,  hydrogenation ,  nitrogen heterocyclic compound ,  polynuclear aromatic compound ,  *asymmetric synthesis ,  catalytic reaction ,  *organic phosphorus acid ,  asymmetric catalyst
Semi thesaurus term： *Benzodiazepines ,  *transfer hydrogenation ,  *dynamic kinetic resolution ,  organocatalysis

Author keywords (5)： dynamic kinetic resolution ,  heterocycles ,  hydrogenation ,  organocatalysis ,  stereoselective synthesis

JST classification (3)： Seven-membered heterocyclic compounds  (CF07110I) ,  Oxidation,reduction  (CF02060T) ,  Other separation methods  (CC01060D)

Substance index (4)： rac-2α^*,4-Diphenyl-2,3-dihydro-1H-1,5-benzodiazepine ,  2α,4β-Diphenyl-2,3,4,5-tetrahydro-1H-1,5-benzodiazepine ,  3-(Benzothiazoline-2-yl)phenol ,  (aR)-2,6-Bis[2,6-diisopropyl-4-(2,4,6-triisopropylphenyl)phenyl]-4-hydroxydinaphtho[2,1-d:1′,2′-f][1,3,2]dioxaphosphepin 4-oxide

Terms in the title (5)： キラル ,  リン酸 ,  移動水素化 ,  不斉合成 ,  動的速度論的分割