Art

J-GLOBAL ID：201602216488359909   Reference number：16A1395580

Lysosomal Trapping Is Present in Retinal Capillary Endothelial Cells: Insight into Its Influence on Cationic Drug Transport at the Inner Blood-Retinal Barrier

リソソームトラッピングは網膜毛細血管内皮細胞に存在する:内側血液網膜関門での陽イオン性薬物輸送に対するその影響についての洞察

Author (5)： Kubo Yoshiyuki (Department of Pharmaceutics, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama) ,  Seko Narumi (Department of Pharmaceutics, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama) ,  Usui Takuya (Department of Pharmaceutics, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama) ,  Akanuma Shin-ichi (Department of Pharmaceutics, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama) ,  Hosoya Ken-ichi (Department of Pharmaceutics, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama)
Material： Biological and Pharmaceutical Bulletin  (Biological & Pharmaceutical Bulletin)
Volume： 39  Issue： 8  Page： 1319-1324(J-STAGE)  Publication year： 2016 
JST Material Number： S0989A  ISSN： 0918-6158  CODEN： BPBLEO  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： human ,...
Semi thesaurus term： *capillary endothelial cell

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Author keywords (8)： inner blood-retinal barrier ,  transport ,  organic cation ,  lysosomal trapping ,  inner blood-retinal barrier ,  transport ,  organic cation ,  lysosomal trapping

JST classification (1)： Basic ophthalmology  (GP01020C)

Reference (37)：

• 1) Mizuno K, Koide T, Yoshimura M, Araie M. Neuroprotective effect and intraocular penetration of nipradilol, a beta-blocker with nitric oxide donative action. Invest. Ophthalmol. Vis. Sci., 42, 688-694 (2001).
• 2) Albino Teixeira A, Azevedo I, Branco D, Rodrigues-Pereira E, Osswald W. Sympathetic denervation caused by long-term noradrenaline infusions; prevention by desipramine and superoxide dismutase. Br. J. Pharmacol., 97, 95-102 (1989).
• 3) Ono Y, Shimazawa M, Ishisaka M, Oyagi A, Tsuruma K, Hara H. Imipramine protects mouse hippocampus against tunicamycin-induced cell death. Eur. J. Pharmacol., 696, 83-88 (2012).
• 4) Ristori C, Filippi L, Dal Monte M, Martini D, Cammalleri M, Fortunato P, la Marca G, Fiorini P, Bagnoli P. Role of the adrenergic system in a mouse model of oxygen-induced retinopathy: antiangiogenic effects of beta-adrenoreceptor blockade. Invest. Ophthalmol. Vis. Sci., 52, 155-170 (2011).
• 5) Rojas JC, Saavedra JA, Gonzalez-Lima F. Neuroprotective effects of memantine in a mouse model of retinal degeneration induced by rotenone. Brain Res., 1215, 208-217 (2008).

Terms in the title (7)： 網膜 ,  毛細血管内皮細胞 ,  内側 ,  血液網膜関門 ,  陽イオン ,  薬物輸送 ,  洞察