Art

J-GLOBAL ID：201602217517780401   Reference number：16A0231365

Vitamin B₁₂ deficiency-induced increase of osteoclastic bone resorption caused by abnormal renal resorption of inorganic phosphorus via Napi2a

ビタミンB₁₂欠乏は,Napi2aを通じた無機リンの異常な腎臓再吸収によって生じる,破骨細胞の骨吸収の増加を誘発した

Author (7)： SHIGA Takahiro (Tokyo Univ. Agriculture, Tokyo, JPN) ,  KIMIRA Yoshifumi (Josai Univ., Saitama, JPN) ,  MANO Hiroshi (Josai Univ., Saitama, JPN) ,  KAWATA Tetsunori (Okayama Univ., Okayama, JPN) ,  TADOKORO Tadahiro (Okayama Univ., Okayama, JPN) ,  SUZUKI Tsukasa (Tokyo Univ. Agriculture, Tokyo, JPN) ,  YAMAMOTO Yuji (Tokyo Univ. Agriculture, Tokyo, JPN)
Material： Bioscience, Biotechnology, and Biochemistry  (Bioscience Biotechnology & Biochemistry)
Volume： 80  Issue： 3  Page： 510-513  Publication year： Mar. 2016 
JST Material Number： G0021A  ISSN： 0916-8451  CODEN： BBBIEJ  Document type： Article
Article type： 短報  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Thesaurus term： *vitamin B12 deficiency ,...
Semi thesaurus term： resorption

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JST classification (2)： Food chemistry,nutritional value  (FJ01020J) ,  Skeletal system  (EJ10030R)

Reference (15)：

• Uekawa A, Katsushima K, Ogata A, et al. Change of epigenetic control of cystathionine beta-synthase gene expression through dietary vitamin B₁₂ is not recovered by methionine supplementation. J. Nutrigenet. Nutrigenomics. 2009;2:29-36.
• Vacek TP, Kalani A, Voor MJ, et al. The role of homocysteine in bone remodeling. Clin. Chem. Lab. Med. 2013;51:579-590.
• Vaes BL, Lute C, Blom HJ, et al. Vitamin B(12) deficiency stimulates osteoclastogenesis via increased homocysteine and methylmalonic acid. Calcif. Tissue Int. 2009;84:413-422.
• Herrmann M, Wildemann B, Wagner A, et al. Experimental folate and vitamin B12 deficiency does not alter bone quality in rats. J. Bone Miner. Res. 2009;24:589-596.
• Tucker KL, Hannan MT, Qiao N, et al. Low plasma vitamin B12 is associated with lower BMD: the framingham osteoporosis study. J. Bone Miner. Res. 2005; 20: 152-158.

Terms in the title (6)： ビタミンB12欠乏 ,  無機リン ,  腎臓再吸収 ,  破骨細胞 ,  骨吸収 ,  誘発