Inhibition of PP2A in MCF-7 cells leads to hormone-independent growth.

HAYASHI Takanori; HIKICHI Masahiro; UTSUMI Toshiaki; HARADA Nobuhiro; YUKITAKE Jun

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J-GLOBAL ID：201602218647916530 Reference number：16A0352845

Inhibition of PP2A in MCF-7 cells leads to hormone-independent growth.

MCF-7細胞におけるPP2Aの阻害はホルモン非依存性の増殖に繋がる

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Volume： 4 Issue： 1 Page： 1-5 Publication year： Mar. 2016
JST Material Number： F1485A ISSN： 2187-7912 CODEN： IJABGQ Document type： Article
Article type：原著論文 Country of issue： Japan (JPN) Language： ENGLISH (EN)

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Chemistry,biochemistry and pathology of tumors(=neoplasms) , Basic research of antitumor(=antineoplastic)drugs , Basic research of enzyme preparations and enzyme inhibitor preparations

Reference (15)：

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Huderson BP, Duplessis TT, Williams CC, et al.: Stable inhibition of specific estrogen receptor alpha (ERalpha) phosphorylation confers increased growth, migration/invasion, and disruption of estradiol signaling in MCF-7 breast cancer cells. Endocrinology, 153: 4144-59, 2012.

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