Art

J-GLOBAL ID：201602220647531174   Reference number：16A0493865

Inhibitory effects of emodin on intestinal tumor development in Min mice

Minマウスにおける腸管腫瘍発生に対するエモジンの阻害効果

Author (8)： SHIMPO Kan (Fujita Health Univ., Mie) ,  CHIHARA Takeshi (Fujita Health Univ., Mie) ,  BEPPU Hidehiko (Fujita Health Univ., Mie) ,  KANEKO Takaaki (Fujita Health Univ., Mie) ,  SHINZATO Masanori (Fujita Health Univ. School of Health Sci.) ,  WAKAMATSU Kazumasa (Fujita Health Univ. School of Health Sci.) ,  HIGASHIGUCHI Takashi (Fujita Health Univ., Aichi, JPN) ,  SONODA Shigeru (Fujita Health Univ., Mie)
Material： 薬理と臨床  (Clinical Pharmacology and Therapy)
Volume： 26  Issue： 2  Page： 45-54  Publication year： May. 25, 2016 
JST Material Number： L1701A  ISSN： 0917-3994  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *intestinal tumor ,...
Semi thesaurus term： genetic variation ,...

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JST classification (1)： Basic research of antitumor(=antineoplastic)drugs  (GW16010A)

Substance index (1)： Emodin

Reference (26)：

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• Shrimali D, Shanmugam MK, Kumar AP, Zhang J, Tan BKH, Ahn KS, Sethi G. Targeted abrogation of diverse signal transduction cascades by emodin for the treatment of inflammatory disorders and cancer. Cancer Lett, 341, 139-49, 2013.
• Chen R, Zhang J, Hu Y, Wang S, Chen M, Wang Y. Potential antineoplastic effects of Aloe-emodin: a comprehensive review. Am J Chin Med, 42, 275-88, 2014.
• Moser AR, Pitot HC, Dove WF: A dominant mutation that predisposes to multiple intestinal neoplasia in the mouse. Science, 247, 322-324, 1990.

Terms in the title (5)： Minマウス ,  腸管 ,  腫瘍発生 ,  エモジン ,  阻害効果