Art

J-GLOBAL ID：201602225836899228   Reference number：16A1349143

Inflammageing assessed by MMP9 in normal Japanese individuals and the patients with Werner syndrome

正常日本人およびウェルナー症候群患者においてMMP9によって評価される炎症

Author (7)： Goto Makoto (Department of Orthopaedics & Rheumatology, East Medical Center, Tokyo Women’s Medical University) ,  Goto Makoto (Division of Anti-ageing and Longevity Sciences, Department of Medical Technology, Faculty of Medical Engineering, Toin University of Yokohama) ,  Goto Makoto (Division of Rheumatology, Nerima-Hikarigaoka Hospital) ,  Chiba Junji (Department of Orthopaedics & Rheumatology, East Medical Center, Tokyo Women’s Medical University) ,  Matsuura Masaaki (Graduate School of Public Health, Teikyo University) ,  Iwaki-Egawa Sachiko (Department of Life Sciences, School of Pharmacy, Hokkaido Pharmaceutical University) ,  Watanabe Yasuhiro (Department of Life Sciences, School of Pharmacy, Hokkaido Pharmaceutical University)
Material： Intractable & Rare Diseases Research  (IRDR)
Volume： 5  Issue： 2  Page： 103-108(J-STAGE)  Publication year： 2016 
JST Material Number： F1228A  ISSN： 2186-3644  CODEN： IRDRA3  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： human ,...
Semi thesaurus term： hsCRP ,...

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Author keywords (5)： Aging ,  C-reactive protein (CRP) ,  inflammageing ,  matrix metalloproteinase-9 (MMP9) ,  Werner syndrome

JST classification (1)： Endocrine diseases  (GL03000I)

Reference (28)：

• 1. Franceschi C, Bonafe M, Valensin S, Olivieri F, De Luca M, Ottaviani E, De Benedictis G. Inflamm-aging. An evolutionary perspective on immunosenescence. Ann NY Acad Sci. 2000; 908:244-254.
• 2. Goto M. Inflammaging (inflammation+aging):A driving force for human aging based on an evolutionarily antagonistic pleiotropy theory? BioSci Trends. 2008; 2:218-230.
• 3. Arima H, Kubo M, Yonemoto K, Doi Y, Ninomiya T, Tanizaki Y, Hata J, Matsumura K, Iida M, Kiyohara Y. High-sensitivity C-reactive protein and coronary heart disease in a general population of Japanese:the Hisayama Study. Arteriroscler Thromb Vasc Biol. 2008; 28:1385-1391.
• 4. Balkwill F, Coussens LM. An inflammatory link. Nature 2004; 431:405-406.
• 5. Goto M, Sugimoto K, Hayashi S, Ogino T, Sugimoto M, Furuichi Y, Matsuura M, Ishikawa Y, Iwaki-Egawa S, Watanabe Y. Aging-associated inflammation in healthy Japanese individuals and patients with Werner syndrome. Exp Gerontol 2012;47:936-939.

Terms in the title (6)： 日本人 ,  ウェルナー症候群 ,  患者 ,  MMP9 ,  評価 ,  炎症