Art

J-GLOBAL ID：201602227700260680   Reference number：16A1226267

Deferasirox, an oral iron chelator, prevents hepatocarcinogenesis and adverse effects of sorafenib

経口鉄キレート剤デフェラシロクスは肝発癌とソラフェニブの有害効果を予防する

Author (13)： Yamamoto Naoki (Department of Gastroenterology and Hepatology, Yamaguchi University Graduate School of Medicine) ,  Yamamoto Naoki (Yamaguchi University Health Administration Center) ,  Yamasaki Takahiro (Department of Gastroenterology and Hepatology, Yamaguchi University Graduate School of Medicine) ,  Yamasaki Takahiro (Department of Oncology and Laboratory Medicine, Yamaguchi University Graduate School of Medicine) ,  Takami Taro (Department of Gastroenterology and Hepatology, Yamaguchi University Graduate School of Medicine) ,  Uchida Koichi (Department of Human Nutrition Faculty of Nursing and Human Nutrition, Yamaguchi Prefectural University) ,  Fujisawa Koichi (Department of Gastroenterology and Hepatology, Yamaguchi University Graduate School of Medicine) ,  Fujisawa Koichi (Center of Research and Education for Regenerative Medicine, Yamaguchi University Graduate School of Medicine) ,  Matsumoto Toshihiko (Department of Gastroenterology and Hepatology, Yamaguchi University Graduate School of Medicine) ,  Matsumoto Toshihiko (Department of Oncology and Laboratory Medicine, Yamaguchi University Graduate School of Medicine) ,  Saeki Issei (Department of Gastroenterology and Hepatology, Yamaguchi University Graduate School of Medicine) ,  Terai Shuji (Division of Gastroenterology and Hepatology, Graduate School of Medical and Dental Sciences, Niigata University) ,  Sakaida Isao (Department of Gastroenterology and Hepatology, Yamaguchi University Graduate School of Medicine)
Material： Journal of Clinical Biochemistry and Nutrition  (JCBN)
Volume： 58  Issue： 3  Page： 202-209(J-STAGE)  Publication year： 2016 
JST Material Number： X0851A  ISSN： 0912-0009  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *chelating reagent ,...
Semi thesaurus term： 手足皮膚症候群

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Author keywords (5)： hand-foot skin syndrome ,  liver cancer ,  liver fibrosis ,  deferasirox ,  sorafenib

JST classification (1)： Basic research of antitumor(=antineoplastic)drugs  (GW16010A)

Substance index (2)： Deferasirox ,  Sorafenib

Reference (35)：

• 1 GLOBOCAN 2012. http://globocan.iarc.fr/Default.aspx.
• 2 Kudo M. Adjuvant therapy after curative treatment for hepatocellular carcinoma. Oncology 2011; 81: 50-55.
• 3 Tan ZM, Sun BC. Effects of antiviral therapy on preventing liver tumorigenesis and hepatocellular carcinoma recurrence. World J Gastroenterol 2013; 19: 8895-8901.
• 4 Sun P, Yang X, He RQ, et al. Antiviral therapy after curative treatment of hepatitis B/C virus-related hepatocellular carcinoma: a systematic review of randomized trials. Hepatol Res 2014; 44: 259-269.
• 5 Nagaoki Y, Hyogo H, Aikata H, et al. Recent trend of clinical features in patients with hepatocellular carcinoma. Hepatol Res 2012; 42: 368-375.

Terms in the title (5)： 鉄キレート剤 ,  デフェラシロクス ,  肝発癌 ,  ソラフェニブ ,  予防