Art

J-GLOBAL ID：201602228340986319   Reference number：16A0782371

New acyclic bis phenylpropanoid and neolignans, from Myristica fragrans Houtt., exhibiting PARP-1 and NF-κB inhibitory effects

PARP-1とNF-κB阻害作用を示すMyristica fragrans Houttからの新規非環式ビスフェニルプロパノイドとネオリグナン

Author (6)： Munoz Acuna Ulyana (Division of Pharmacy Practice and Science, College of Pharmacy, The Ohio State University, 141N Parks Hall, 500 W. 12th Avenue, Columbus, OH 43210, United States) ,  Munoz Acuna Ulyana (Division of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, The Ohio State University, 141N Parks Hall, 500 W. 12th Avenue, Columbus, OH 43210, United States) ,  Carcache Peter J. Blanco (Division of Pharmacy Practice and Science, College of Pharmacy, The Ohio State University, 141N Parks Hall, 500 W. 12th Avenue, Columbus, OH 43210, United States) ,  Matthew Susan (Division of Pharmacy Practice and Science, College of Pharmacy, The Ohio State University, 141N Parks Hall, 500 W. 12th Avenue, Columbus, OH 43210, United States) ,  Carcache de Blanco Esperanza J. (Division of Pharmacy Practice and Science, College of Pharmacy, The Ohio State University, 141N Parks Hall, 500 W. 12th Avenue, Columbus, OH 43210, United States) ,  Carcache de Blanco Esperanza J. (Division of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, The Ohio State University, 141N Parks Hall, 500 W. 12th Avenue, Columbus, OH 43210, United States)
Material： Food Chemistry  (Food Chem)
Volume： 202  Page： 269-275  Publication year： Jul. 01, 2016 
JST Material Number： H0766A  ISSN： 0308-8146  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Thesaurus term： *Myristica fragrans ,  *seed coat ,  *phenolic compound ,  *secondary metabolite ,  extraction liquid ,  solvent extraction ,  preparative isolation ,  thin-layer chromatography ,  reversed-phase HPLC ,  proton magnetic resonance ,  13C NMR ,  absolute configuration ,  ADP ribosyltransferase ,  enzyme inhibition ,  activity(property) ,  NF-kappaB ,  Ras protein ,  bioassay ,  lignan ,  antitumor drug ,  immunosuppressant ,  food ingredient ,  structure analysis ,  alcohol ,  aromatic compound ,  fatty acid ,  carboxylate(ester)
Semi thesaurus term： K-ras ,  NF kappa B inhibitor ,  PARP-1 ,  neolignan ,  phenylpropanoid ,  methanol extract ,  functional ingredient ,  *aril ,  inhibitory activity

Author keywords (7)： Myristica fragrans ,  Mace ,  Neolignans ,  Acyclic bisphenyl propanoids ,  PARP-1 ,  NF-κB ,  K-Ras

JST classification (3)： Seasonings,spices(=condiments)  (FJ10010W) ,  Food chemistry,nutritional value  (FJ01020J) ,  Plant biochemistry  (EH01050J)

Substance index (2)： Benzyl alcohol ,  Acetic acid ethyl

Terms in the title (6)： PARP-1 ,  NF-κB ,  阻害作用 ,  Myristica ,  環 ,  ネオリグナン