Art

J-GLOBAL ID：201602232759349728   Reference number：16A1277077

Biological roles and therapeutic potential of G protein-coupled receptors for free fatty acids and metabolic intermediates

遊離脂肪酸と代謝中間体に対するG蛋白質結合受容体の生物学的役割と治療への可能性

Author (2)： Suzuki Kenji (College of Pharmaceutical Sciences, Ritsumeikan University) ,  Kaneko-Kawano Takako (College of Pharmaceutical Sciences, Ritsumeikan University)
Material： Journal of Physical Fitness and Sports Medicine  (J Phys Fit Sports Med)
Volume： 5  Issue： 3  Page： 213-227(J-STAGE)  Publication year： 2016 
JST Material Number： L8465A  ISSN： 2186-8131  Document type： Article
Article type： 文献レビュー  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： free fatty acid ,...
Semi thesaurus term： *G protein-coupled receptor ,...

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Author keywords (5)： G protein-coupled receptor ,  free fatty acid ,  ketone body ,  obesity ,  diabetes

JST classification (2)： Metabolism and nutrition of lipids  (EJ02034Q) ,  Biochemistry of antigens,antibodies,complements  (ED04020L)

Substance index (2)： 3-Hydroxybutyric acid ,  Lactic acid

Reference (181)：

• 1) Bockaert J and Pin JP. 1999. Molecular tinkering of G protein-coupled receptors: an evolutionary success. EMBO J 18: 1723-1729.
• 2) Rask-Andersen M, Almén MS and Schiöth HB. 2011. Trends in the exploitation of novel drug targets. Nat Rev Drug Discov 10: 579-590.
• 3) Hall JE. 2003. The kidney, hypertension, and obesity. Hypertension 41: 625-633.
• 4) Faulds MH and Dahlman-Wright K. 2012. Metabolic diseases and cancer risk. Curr Opin Oncol 24: 58-61.
• 5) Hua F, Yu JJ and Hu ZW. 2016. Diabetes and cancer, common threads and missing links. Cancer Lett 374: 54-61.

Terms in the title (7)： 遊離脂肪酸 ,  代謝中間体 ,  G蛋白質結合受容体 ,  生物学 ,  役割 ,  治療 ,  可能性