Art

J-GLOBAL ID：201602238146644223   Reference number：16A0713160

Direct enantioseparation of diarylmethylamines with an ortho-hydroxy group via diastereomeric salt formation and their application to the enantioselective addition reaction of diethylzinc

ジアステレオマ塩形成を経由したortho-ヒドロキシ基を持つジアリールメチルアミン類の直接的エナンチオ分離とジエチル亜鉛のエナンチオ選択的付加反応へのそれらの応用

Author (4)： Kodama Koichi (Graduate School of Science and Engineering, Saitama University, 255 Shimo-Okubo, Sakura-ku, Saitama 338-8570, Japan) ,  Hayashi Naoki (Graduate School of Science and Engineering, Saitama University, 255 Shimo-Okubo, Sakura-ku, Saitama 338-8570, Japan) ,  Yoshida Yasuhiko (Graduate School of Engineering, Toyo University, 2100 Kujirai, Kawagoe, Saitama, 350-8585, Japan) ,  Hirose Takuji (Graduate School of Science and Engineering, Saitama University, 255 Shimo-Okubo, Sakura-ku, Saitama 338-8570, Japan)
Material： Tetrahedron  (Tetrahedron Symposia-in-Print)
Volume： 72  Issue： 10  Page： 1387-1394  Publication year： Mar. 10, 2016 
JST Material Number： E0234A  ISSN： 0040-4020  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Thesaurus term： diastereomer ,  purity test ,  atom ,  stereochemistry ,  *separation ,  chemical synthesis ,  crystal structure analysis ,  molecular recognition ,  water molecule ,  t-butyl group ,  *condensation reaction ,  reaction mechanism ,  *asymmetric synthesis ,  proton magnetic resonance ,  13C NMR ,  MALDI-TOF MS ,  *aminoalcohol ,  hydroxy group ,  TOF ,  aromatic aldehyde
Semi thesaurus term： hydroxyl group ,  enantiomeric purity ,  stereogenic center ,  *enantiomer separation ,  enantioselective synthesis ,  chiral recognition ,  organic reaction mechanism ,  asymmetric synthetic reaction ,  1H-NMR ,  C13NMR ,  MALDI-TOF ,  Amino Alcohols

Author keywords (5)： Enantioseparation ,  Diastereomeric salt ,  Chirality ,  Asymmetric synthesis ,  Aminoalcohol

JST classification (4)： Stereochemistry of organic reaction  (CF02130V) ,  Addition reaction,elimination reaction  (CF02030M) ,  Aromatic monocyclic amine,imine,quaternary ammonium,immonium compounds  (CF05050D) ,  Aromatic monocyclic hydroxy compounds  (CF05070Z)

Substance index (4)： Diethyl zinc ,  Benzaldehyde ,  2-[(S)-α-Aminobenzyl]phenol ,  2-[(R)-α-Aminobenzyl]phenol

Terms in the title (7)： ジアステレオマ ,  塩 ,  ヒドロキシ基 ,  エナンチオ分離 ,  ジエチル亜鉛 ,  付加反応 ,  応用