Art

J-GLOBAL ID：201602248889981523   Reference number：16A1114420

Nicotine enhances the malignant potential of human pancreatic cancer cells via activation of atypical protein kinase C

ニコチンは非定型蛋白質キナーゼCの活性化を介してヒト膵臓癌細胞の悪性度を増強する

Author (15)： HANAKI Takehiko (Tottori Univ. Fac. of Medicine, Yonago, JPN) ,  HORIKOSHI Yosuke (Tottori Univ. Fac. of Medicine, Yonago, JPN) ,  NAKASO Kazuhiro (Tottori Univ. Fac. of Medicine, Yonago, JPN) ,  NAKASONE Masato (Tottori Univ. Fac. of Medicine, Yonago, JPN) ,  KITAGAWA Yoshinori (Tottori Univ. Fac. of Medicine, Yonago, JPN) ,  AMISAKI Masataka (Tottori Univ. Fac. of Medicine, Yonago, JPN) ,  ARAI Yosuke (Tottori Univ. Fac. of Medicine, Yonago, JPN) ,  TOKUYASU Naruo (Tottori Univ. Fac. of Medicine, Yonago, JPN) ,  SAKAMOTO Teruhisa (Tottori Univ. Fac. of Medicine, Yonago, JPN) ,  HONJO Soichiro (Tottori Univ. Fac. of Medicine, Yonago, JPN) ,  SAITO Hiroaki (Tottori Univ. Fac. of Medicine, Yonago, JPN) ,  IKEGUCHI Masahide (Tottori Univ. Fac. of Medicine, Yonago, JPN) ,  YAMASHITA Kazunari (Yokohama City Univ., Yokohama, JPN) ,  OHNO Shigeo (Yokohama City Univ., Yokohama, JPN) ,  MATSURA Tatsuya (Tottori Univ. Fac. of Medicine, Yonago, JPN)
Material： Biochimica et Biophysica Acta  (BBA. Biomembranes)
Volume： 1860  Issue： 11,Pt.A  Page： 2404-2415  Publication year： Nov. 2016 
JST Material Number： B0207A  ISSN： 0005-2728  CODEN： BBBMBS  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Thesaurus term： *pancreatic tumor ,  human(primates) ,  tumor cell ,  degree ,  *tobacco alkaloid ,  *protein kinase C ,  *enzyme activation ,  tumor process ,  phosphatidylinositol 3-kinase ,  acetylcholine receptor ,  cell proliferation ,  cell migration ,  enzyme activity ,  immunohistochemistry ,  peritoneal neoplasm ,  cell physiology ,  serine-threonine kinase ,  phosphorylation ,  experimental disease ,  mouse(animal) ,  *neoplasm staging ,  cell differentiation ,  nitrogen heterocyclic compound ,  drug
Semi thesaurus term： Akt ,  ニコチンアセチルコリン受容体 ,  cellular invasion ,  malignancy of neoplasm ,  epithelial-mesenchymal transition ,  *atypical protein kinase C

JST classification (3)： Tumors(=neoplasms)of digestive system  (GH04000D) ,  Alkaloids  (CF10030D) ,  Enzyme in general  (EB09010D)

Substance index (1)： Nicotine

Terms in the title (9)： ニコチン ,  定型 ,  蛋白質キナーゼC ,  活性化 ,  ヒト ,  膵臓癌 ,  細胞 ,  悪性度 ,  増強