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J-GLOBAL ID：201602252334102098   Reference number：16A1196844

Effect of pH on the Misincorporation Rate of DNA Polymerase η

DNAポリメラーゼηの誤取込率に対するpHの影響

Author (3)： Nishimoto Naomi (Graduate School of Science and Technology, Kumamoto University) ,  Suzuki Motoshi (Division of Molecular Carcinogenesis, Center for Neural Disease and Cancer, Nagoya University Graduate School of Medicine) ,  Izuta Shunji (Graduate School of Science and Technology, Kumamoto University)
Material： Biological and Pharmaceutical Bulletin  (Biological & Pharmaceutical Bulletin)
Volume： 39  Issue： 6  Page： 953-958(J-STAGE)  Publication year： 2016 
JST Material Number： S0989A  ISSN： 0918-6158  CODEN： BPBLEO  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *DNA polymerase ,...
Semi thesaurus term： ポリメラーゼ

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Author keywords (8)： misincorporation ,  DNA polymerase ,  pH ,  mutation ,  misincorporation ,  DNA polymerase ,  pH ,  mutation

JST classification (1)： Molecular genetics in general  (EC02010J)

Substance index (1)： dGTP

Reference (32)：

• 1) Bebenek K, Kunkel TA. Functions of DNA polymerases. Advances in Protein Chemistry. DNA Repair and Replication. (Yang W ed.) Vol. 69, Elsevier Academic Press, San Diego, pp. 137-165 (2004).
• 2) Burgers PMJ, Koonin EV, Bruford E, Blanco L, Burtis KC, Christman MF, Copeland WC, Friedberg EC, Hanaoka F, Hinkle DC, Lawrence CW, Nakanishi M, Ohmori H, Prakash L, Prakash S, Reynaud CA, Sugino A, Todo T, Wang Z, Weill JC, Woodgate R. Eukaryotic DNA polymerases; proposal for a revised nomenclature. J. Biol. Chem., 276, 43487-43490 (2001).
• 3) Masutani C, Kusumoto R, Yamada A, Dohmae N, Yokoi M, Yuasa M, Araki M, Iwai S, Takio K, Hanaoka F. The XPV (Xeroderma pigmentosum variant) gene encodes human DNA polymerase η. Nature, 399, 700-704 (1999).
• 4) Vaisman A, Lehman AR, Woodgate R. DNA polymerases η and ι. Advances in Protein Chemistry. DNA Repair and Replication. (Yang W ed.) Vol. 69, Elsevier Academic Press, San Diego, pp. 205-228 (2004).
• 5) Masutani C, Araki M, Yamada A, Kusumoto R, Nogimori T, Maekawa T, Iwai S, Hanaoka F. Xeroderma pigmentosum variant (XP-V) correcting protein from HeLa cells has a thymine dimer bypass DNA polymerase activity. EMBO J., 18, 3491-3501 (1999).

Terms in the title (3)： DNAポリメラーゼη ,  取込 ,  pH