Art

J-GLOBAL ID：201602258224458176   Reference number：16A1213004

Eplerenone improves carotid intima-media thickness (IMT) in patients with primary aldosteronism

エプレレノンは原発性アルドステロン症患者における頸動脈内膜中膜複合体厚(IMT)を改善する

Author (12)： Matsuda Yayoi (Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812-8582, Japan) ,  Matsuda Yayoi (Division of Hepatology, Diabetes, Metabolism and Endocrinology, Faculty of Medicine, Saga University, Saga 849-8501, Japan) ,  Kawate Hisaya (Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812-8582, Japan) ,  Kawate Hisaya (Graduate School of Health and Nutrition Sciences, Nakamura Gakuen University, Fukuoka 814-0198, Japan) ,  Matsuzaki Chitose (Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812-8582, Japan) ,  Sakamoto Ryuichi (Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812-8582, Japan) ,  Sakamoto Ryuichi (Department of Metabolism and Endocrinology, Clinical Research Institute, National Hospital Organization Kyushu Medical Center, Fukuoka 810-8563, Japan) ,  Shibue Kimitaka (Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812-8582, Japan) ,  Ohnaka Keizo (Department of Geriatric Medicine, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812-8582, Japan) ,  Anzai Keizo (Division of Hepatology, Diabetes, Metabolism and Endocrinology, Faculty of Medicine, Saga University, Saga 849-8501, Japan) ,  Nomura Masatoshi (Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812-8582, Japan) ,  Takayanagi Ryoichi (Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812-8582, Japan)
Material： Endocrine Journal  (Endocr J)
Volume： 63  Issue： 3  Page： 249-255(J-STAGE)  Publication year： 2016 
JST Material Number： F0625A  ISSN： 0918-8959  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： human(primates) ,...
Semi thesaurus term： Carotid Intima-Media Thickness ,...

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Author keywords (4)： Primary aldosteronism ,  IMT ,  Eplerenone ,  Atherosclerosis

JST classification (2)： Endocrine diseases  (GL03000I) ,  Clinical medicine on cardiovascular system in general  (GJ01030V)

Substance index (2)： Aldosterone ,  Eplerenone

Reference (36)：

• 1. Mattsson C, Young WF Jr (2006) Primary aldosteronism: diagnostic and treatment strategies. Nat Clin Pract Nephrol 2: 198-208.
• 2. Funder JW, Carey RM, Fardella C, Gomez-Sanchez CE, Mantero F, Stowasser M, et al. (2008) Case detection, diagnosis, and treatment of patients with primary aldosteronism: an endocrine society clinical practice guideline. J Clin Endocrinol Metab 93: 3266-3281.
• 3. Gordon RD, Stowasser M, Tunny TJ, Klemm SA, Rutherford JC (1994) High incidence of primary aldosteronism in 199 patients referred with hypertension. Clin Exp Pharmacol Physiol 21: 315-318.
• 4. Schwartz GL, Turner ST (2005) Screening for primary aldosteronism in essential hypertension: diagnostic accuracy of the ratio of plasma aldosterone concentration to plasma renin activity. Clin Chem 51: 386-394.
• 5. Rossi GP, Bernini G, Caliumi C, Desideri G, Fabris B, et al. (2006) PAPY Study Investigators. A prospective study of the prevalence of primary aldosteronism in 1,125 hypertensive patients. J Am Coll Cardiol 48: 2293-2300.

Terms in the title (5)： エプレレノン ,  原発性アルドステロン症 ,  患者 ,  頸動脈内膜中膜複合体厚 ,  IMT