Art

J-GLOBAL ID：201602259094518651   Reference number：16A1395449

Plantar injection of formalin in rats reduces the expression of a potassium chroride cotransporter KCC2 in the spinal cord and a kinase inhibitor suppresses this reduction

ラットにおけるホルマリンの足底注射は脊髄における塩化カリウム共輸送体KCC2発現を低減しキナーゼ阻害剤はこの低減を抑制する

Author (7)： TSURUGA Kenkichi ,  HASHIMOTO Toshikazu ,  KATO Ryoko ,  KATO Rui ,  UCHIDA Yousuke ,  HASE Tetsutaro ,  MORIMOTO Yuji
Material： Biomedical Research  (Biomed Res)
Volume： 37  Issue： 4  Page： 243-249(J-STAGE)  Publication year： 2016 
JST Material Number： Z0236B  ISSN： 0388-6107  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： receptor tyrosine kinase ,...
Semi thesaurus term： *NGF receptor ,...

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JST classification (3)： Basic neurology  (GN01020W) ,  Basic research of enzyme preparations and enzyme inhibitor preparations  (GW21010W) ,  Receptors on cell membrane  (EF04030C)

Substance index (2)： Formaldehyde ,  K-252a

Reference (20)：

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• 3 Coull JA, Boudreau D, Bachand K, Prescott SA, Nault F, Sík A, DeKoninck P and DeKoninck Y (2003) Trans-synaptic shift in anion gradient in spinal lamina I neurons as a mechanism of neuropathic pain. Nature 424, 938-942.
• 4 Galan A and Cervero F (2005) Painful stimuli induce in vivo phosphorylation and membrane mobilization of mouse spinal cold NLCC1 co-transporter. Neuroscience 133, 245-252.
• 5 Garraway SM, Petruska JC and Mendell LM (2003) BDNF sensitizes the response of lamina II neurons to high threshold primary afferent inputs. Eur J Neurosci 18, 2467-2476.

Terms in the title (10)： ラット ,  ホルマリン ,  足底 ,  注射 ,  脊髄 ,  塩化カリウム ,  共輸送体 ,  KCC2 ,  発現 ,  キナーゼ阻害剤