Art

J-GLOBAL ID：201602260003938160   Reference number：16A1196838

Carbonyl Compounds in the Gas Phase of Cigarette Mainstream Smoke and Their Pharmacological Properties

タバコ主流煙の気相中のカルボニル化合物とその薬理学的特性

Author (4)： Horinouchi Takahiro (Department of Cellular Pharmacology, Hokkaido University Graduate School of Medicine) ,  Higashi Tsunehito (Department of Cellular Pharmacology, Hokkaido University Graduate School of Medicine) ,  Mazaki Yuichi (Department of Cellular Pharmacology, Hokkaido University Graduate School of Medicine) ,  Miwa Soichi (Department of Cellular Pharmacology, Hokkaido University Graduate School of Medicine)
Material： Biological and Pharmaceutical Bulletin  (Biological & Pharmaceutical Bulletin)
Volume： 39  Issue： 6  Page： 909-914(J-STAGE)  Publication year： 2016 
JST Material Number： S0989A  ISSN： 0918-6158  CODEN： BPBLEO  Document type： Article
Article type： 解説  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *aerosol (suspended solids) ,...
Semi thesaurus term： *tobacco smoke ,...

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Author keywords (12)： cigarette smoke extract (CSE) ,  acrolein (ACR) ,  methyl vinyl ketone (MVK) ,  protein kinase C (PKC) ,  reduced nicotinamide adenine dinucleotide phosphate (NADPH) oxidase (NOX) ,  protein carbonylation ,  cigarette smoke extract (CSE) ,  acrolein (ACR) ,  methyl vinyl ketone (MVK) ,  protein kinase C (PKC) ,  reduced nicotinamide adenine dinucleotide phosphate (NADPH) oxidase (NOX) ,  protein carbonylation

JST classification (1)： Toxicity of chemical substances in general  (GZ02010C)

Substance index (2)： Acrolein ,  Methyl vinyl ketone

Reference (41)：

• 1) IARC Working Group on the Evaluation of Carcinogenic Risks to Humans. Tabacco smoke and involuntary smoking. IARC Monogr. Eval. Carcinog. Risks Hum., 83, 1-1438 (2004).
• 2) Smith CJ, Fischer TH. Particulate and vapor phase constituents of cigarette mainstream smoke and risk of myocardial infarction. Atherosclerosis, 158, 257-267 (2001).
• 3) Green CR, Rodgman A. The Tobacco Chemists’ Research Conference: a half century forum for advances in analytical methodology of tobacco and its products. Recent Adv. Tobacco Sci., 22, 131-304 (1996).
• 4) Church DF, Pryor WA. Free-radical chemistry of cigarette smoke and its toxicological implications. Environ. Health Perspect., 64, 111-126 (1985).
• 5) Higashi T, Mai Y, Noya Y, Horinouchi T, Terada K, Hoshi A, Nepal P, Harada T, Horiguchi M, Hatate C, Kuge Y, Miwa S. A simple and rapid method for standard preparation of gas phase extract of cigarette smoke. PLoS ONE, 9, e107856 (2014).

Terms in the title (5)： タバコ ,  主流煙 ,  気相 ,  カルボニル化合物 ,  薬理学