Art

J-GLOBAL ID：201602267296750704   Reference number：16A1332194

Forward-genetics analysis of sleep in randomly mutagenized mice

ランダムに変異を起こさせたマウスにおける睡眠の順遺伝学的解析

Author (44)： FUNATO Hiromasa (Univ. Tsukuba, Ibaraki, JPN) ,  MIYOSHI Chika (Univ. Tsukuba, Ibaraki, JPN) ,  FUJIYAMA Tomoyuki (Univ. Tsukuba, Ibaraki, JPN) ,  KANDA Takeshi (Univ. Tsukuba, Ibaraki, JPN) ,  SATO Makito (Univ. Tsukuba, Ibaraki, JPN) ,  WANG Zhiqiang (Univ. Tsukuba, Ibaraki, JPN) ,  MA Jing (Univ. Tsukuba, Ibaraki, JPN) ,  IKKYU Aya (Univ. Tsukuba, Ibaraki, JPN) ,  KAKIZAKI Miyo (Univ. Tsukuba, Ibaraki, JPN) ,  HOTTA-HIRASHIMA Noriko (Univ. Tsukuba, Ibaraki, JPN) ,  KANNO Satomi (Univ. Tsukuba, Ibaraki, JPN) ,  KOMIYA Haruna (Univ. Tsukuba, Ibaraki, JPN) ,  ASANO Fuyuki (Univ. Tsukuba, Ibaraki, JPN) ,  HONDA Takato (Univ. Tsukuba, Ibaraki, JPN) ,  KIM Staci J. (Univ. Tsukuba, Ibaraki, JPN) ,  HARANO Kanako (Univ. Tsukuba, Ibaraki, JPN) ,  MURAMOTO Hiroki (Univ. Tsukuba, Ibaraki, JPN) ,  YONEZAWA Toshiya (Univ. Tsukuba, Ibaraki, JPN) ,  MIYAZAKI Shinichi (Univ. Tsukuba, Ibaraki, JPN) ,  CONNOR Linzi (Univ. Tsukuba, Ibaraki, JPN) ,  HAYASHI Yu (Univ. Tsukuba, Ibaraki, JPN) ,  LIU Qinghua (Univ. Tsukuba, Ibaraki, JPN) ,  TAKAHASHI Joseph S. (Univ. Tsukuba, Ibaraki, JPN) ,  YANAGISAWA Masashi (Univ. Tsukuba, Ibaraki, JPN) ,  FUNATO Hiromasa (Toho Univ., Tokyo, JPN) ,  SATO Makito (Univ. Texas Southwestern Medical Center, Texas, USA) ,  YANAGISAWA Masashi (Univ. Texas Southwestern Medical Center, Texas, USA) ,  NAKANE Shin (Nagoya City Univ., Aichi, JPN) ,  TOMITA Jun (Nagoya City Univ., Aichi, JPN) ,  KUME Kazuhiko (Nagoya City Univ., Aichi, JPN) ,  MIZUNO Seiya (Univ. Tsukuba, Ibaraki, JPN) ,  SUGIYAMA Fumihiro (Univ. Tsukuba, Ibaraki, JPN) ,  TAKAHASHI Satoru (Univ. Tsukuba, Ibaraki, JPN) ,  KUMAR Vivek (Univ. Texas Southwestern Medical Center, Texas, USA) ,  TAKAHASHI Joseph S. (Univ. Texas Southwestern Medical Center, Texas, USA) ,  KUMAR Vivek (Jackson Lab., Maine, USA) ,  MIURA Ikuo (RIKEN, Ibaraki, JPN) ,  SUZUKI Tomohiro (RIKEN, Ibaraki, JPN) ,  WAKANA Shigeharu (RIKEN, Ibaraki, JPN) ,  WATANABE Atsushi (National Center for Geriatrics and Gerontology, Aichi, JPN) ,  ABE Manabu (Niigata Univ., Niigata, JPN) ,  SAKIMURA Kenji (Niigata Univ., Niigata, JPN) ,  HAYASHI Yu (JST-PRESTO, Saitama, JPN) ,  LIU Qinghua (Univ. Texas Southwestern Medical Center, Texas, USA)
Material： Nature (London)  (Nature (Lond))
Volume： 539  Issue： 7629  Page： 378-383  Publication year： Nov. 17, 2016 
JST Material Number： D0193B  ISSN： 0028-0836  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Thesaurus term： Mus musculus ,  genetics ,  Sleep ,  *REM sleep ,  *non-REM sleep ,  mechanism ,  *electroencephalogram ,  *electromyogram ,  Arousal ,  *gene ,  RNA splicing ,  phosphorylation ,  *protein kinase ,  *Ion Channels ,  missense mutation ,  molecular mechanism ,  protein phosphorylation ,  Genetic Variation ,  Myomorpha ,  natural science ,  molecular genetic phenomenon ,  *Ion Transport ,  *transportation ,  *Biological Transport ,  *transmembrane protein ,  *ion transport(in vivo)
Semi thesaurus term： variation(biology) ,  ランダム変異 ,  細胞機構 ,  electro-encephalogram ,  *Sik3遺伝子 ,  プロテインキナーゼ遺伝子 ,  splicing (genetics) ,  SIK3 ,  NALCN ,  Mutation, Missense

JST classification (1)： Basic neurology  (GN01020W)

Terms in the title (6)： 変異 ,  マウス ,  睡眠 ,  順 ,  遺伝学 ,  解析