Art

J-GLOBAL ID：201602274369587361   Reference number：16A1321243

Ligand Activity of Group 15 Compounds Possessing Triphenyl Substituent for the RXR and PPARγ Nuclear Receptors

RXRおよびPPARγ核内受容体に対するトリフェニル置換基を持つグループ15化合物のリガンド活性

Author (7)： Hiromori Youhei (Laboratory of Hygienic Chemistry and Molecular Toxicology, Gifu Pharmaceutical University) ,  Hiromori Youhei (Department of Pharmacy, College of Pharmacy, Kinjo Gakuin University) ,  Ido Akiko (Laboratory of Hygienic Chemistry and Molecular Toxicology, Gifu Pharmaceutical University) ,  Aoki Akira (Laboratory of Hygienic Chemistry and Molecular Toxicology, Gifu Pharmaceutical University) ,  Kimura Tomoki (Department of Life Science, Faculty of Science and Engineering, Setsunan University) ,  Nagase Hisamitsu (Laboratory of Hygienic Chemistry and Molecular Toxicology, Gifu Pharmaceutical University) ,  Nakanishi Tsuyoshi (Laboratory of Hygienic Chemistry and Molecular Toxicology, Gifu Pharmaceutical University)
Material： Biological and Pharmaceutical Bulletin  (Biological & Pharmaceutical Bulletin)
Volume： 39  Issue： 10  Page： 1596-1603(J-STAGE)  Publication year： 2016 
JST Material Number： S0989A  ISSN： 0918-6158  CODEN： BPBLEO  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *PPAR gamma ,...
Semi thesaurus term： Ligands ,...

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Author keywords (10)： peroxisome proliferator-activated receptor ,  retinoid X receptor ,  triphenylarsine ,  triphenylbismuth ,  triphenylphosphine oxide ,  peroxisome proliferator-activated receptor ,  retinoid X receptor ,  triphenylarsine ,  triphenylbismuth ,  triphenylphosphine oxide

JST classification (1)： Toxicity of organic compounds  (GZ02030Y)

Substance index (3)： Triphenylarsine ,  Triphenylbismuthine ,  Triphenylphosphine

Reference (30)：

• 1) Mitsunobu O, Yamada M, Mukaiyama T. Preparation of esters of phosphoric acid by the reaction of trivalent phosphorus compounds with diethyl azodicarboxylate in the presence of alcohols. Bull. Chem. Soc. Jpn., 40, 935-939 (1967).
• 2) Staudinger H, Meyer J. Über neue organische Phosphorverbindungen III. Phosphinmethylenderivate und phosphinimine. Helv. Chim. Acta, 2, 635-646 (1919).
• 3) Wittig G, Schöllkopf U. Über Triphenyl-phosphin-methylene als olefinbildende Reagenzien (I). Mitteil. Chem. Ber., 87, 1318-1330 (1954).
• 4) Emery RJ, Papadaki M, Freitas Dos Santos LM, Mantzavinos D. Extent of sonochemical degradation and change of toxicity of a pharmaceutical precursor (triphenylphosphine oxide) in water as a function of treatment conditions. Environ. Int., 31, 207-211 (2005).
• 5) Richoll SM, Colon I. Determination of triphenylphosphine oxide in active pharmaceutical ingredients by hollow-fiber liquid-phase microextraction followed by reversed-phase liquid chromatography. J. Chromatogr. A, 1127, 147-153 (2006).

Terms in the title (9)： RXR ,  PPARγ ,  核内受容体 ,  トリ ,  フェニル ,  置換基 ,  グループ ,  リガンド ,  活性