Art

J-GLOBAL ID：201602277072126435   Reference number：16A1196845

Characterization of Ocular Iontophoretic Drug Transport of Ionic and Non-ionic Compounds in Isolated Rabbit Cornea and Conjunctiva

単離したウサギ角膜および結膜におけるイオン性および非イオン性化合物の眼イオン泳動的薬物輸送の特性解析

Author (8)： Sekijima Hidehisa (Department of Hospital Pharmacy, Faculty of Pharmaceutical Sciences, Josai University) ,  Ehara Junya (Department of Hospital Pharmacy, Faculty of Pharmaceutical Sciences, Josai University) ,  Hanabata Yusuke (Department of Hospital Pharmacy, Faculty of Pharmaceutical Sciences, Josai University) ,  Suzuki Takumi (Department of Hospital Pharmacy, Faculty of Pharmaceutical Sciences, Josai University) ,  Kimura Soichiro (Department of Hospital Pharmacy, Faculty of Pharmaceutical Sciences, Josai University) ,  Lee Vincent H. L. (School of Pharmacy, The Chinese University of Hong Kong) ,  Morimoto Yasunori (Research Institute of TTS Technology) ,  Ueda Hideo (Department of Hospital Pharmacy, Faculty of Pharmaceutical Sciences, Josai University)
Material： Biological and Pharmaceutical Bulletin  (Biological & Pharmaceutical Bulletin)
Volume： 39  Issue： 6  Page： 959-968(J-STAGE)  Publication year： 2016 
JST Material Number： S0989A  ISSN： 0918-6158  CODEN： BPBLEO  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： hare ,...
Semi thesaurus term： fluorescein isothiocyanate-dextran ,...

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Author keywords (12)： ocular drug delivery ,  physical enhancement ,  iontophoresis ,  electric current ,  cornea ,  conjunctiva ,  ocular drug delivery ,  physical enhancement ,  iontophoresis ,  electric current ,  cornea ,  conjunctiva

JST classification (2)： Basic ophthalmology  (GP01020C) ,  Physicochemical pharmacy in general  (GV01010J)

Substance index (2)： Benzoic acid sodium ,  Lidocaine hydrochloride

Reference (42)：

• 1) Ahmed I, Patton TF. Importance of the noncorneal absorption route in topical ophthalmic drug delivery. Invest. Ophthalmol. Vis. Sci., 26, 584-587 (1985).
• 2) Urtti A, Salminen L. Minimizing systemic absorption of topically administered ophthalmic drugs. Surv. Ophthalmol., 37, 435-456 (1993).
• 3) Kompella UB, Kadam RS, Lee VHL. Recent advances in ophthalmic drug delivery. Ther. Deliv, 1, 435-456 (2010).
• 4) Souza JG, Dias K, Pereira TA, Bernardi DS, Lopez RFV. Topical delivery of ocular therapeutics: carrier systems and physical methods. J. Pharm. Pharmacol., 66, 507-530 (2014).
• 5) Kalia YN, Naik A, Garrison J, Guy RH. Iontophoretic drug delivery. Adv. Drug Deliv. Rev., 56, 619-658 (2004).

Terms in the title (10)： 単離 ,  ウサギ ,  角膜 ,  結膜 ,  イオン性 ,  イオン性化合物 ,  眼 ,  イオン泳動 ,  薬物輸送 ,  特性解析