Art

J-GLOBAL ID：201602279398298865   Reference number：16A1226405

Anti-tumor effect of bevacizumab on a xenograft model of feline mammary carcinoma

ネコ科乳癌の異種移植モデルにおけるベバシズマブの抗腫瘍作用

Author (8)： MICHISHITA Masaki (Department of Veterinary Pathology, Nippon Veterinary and Life Science University, 1-7-1 Kyonan-cho, Musashino, Tokyo 180-8602, Japan) ,  OHTSUKA Aya (Department of Veterinary Pathology, Nippon Veterinary and Life Science University, 1-7-1 Kyonan-cho, Musashino, Tokyo 180-8602, Japan) ,  NAKAHIRA Rei (Department of Veterinary Pathology, Nippon Veterinary and Life Science University, 1-7-1 Kyonan-cho, Musashino, Tokyo 180-8602, Japan) ,  TAJIMA Tsuyoshi (Department of Veterinary Pharmacology, Nippon Veterinary and Life Science University, 1-7-1 Kyonan-cho, Musashino, Tokyo 180-8602, Japan) ,  NAKAGAWA Takayuki (Department of Veterinary Surgery, The University of Tokyo, 1-1-1 Yayoi, Bunkyo, Tokyo 113-8657, Japan) ,  SASAKI Nobuo (Department of Veterinary Surgery, The University of Tokyo, 1-1-1 Yayoi, Bunkyo, Tokyo 113-8657, Japan) ,  ARAI Toshiro (Department of Veterinary Biochemistry, Nippon Veterinary and Life Science University, 1-7-1 Kyonan-cho, Musashino, Tokyo 180-8602, Japan) ,  TAKAHASHI Kimimasa (Department of Veterinary Pathology, Nippon Veterinary and Life Science University, 1-7-1 Kyonan-cho, Musashino, Tokyo 180-8602, Japan)
Material： Journal of Veterinary Medical Science  (日本獣医学会会誌)
Volume： 78  Issue： 4  Page： 685-689(J-STAGE)  Publication year： 2016 
JST Material Number： F0905A  ISSN： 0916-7250  Document type： Article
Article type： 短報  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *Felidae ,...
Semi thesaurus term： Bevacizumab ,...

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Author keywords (4)： bevacizumab ,  feline mammary carcinoma ,  vascular endothelial growth factor (VEGF) ,  xenograft

JST classification (3)： Dogs,cats  (FD06010P) ,  Experimental treatment for tumors  (GE02040Y) ,  Exocrine glands  (EJ11020N)

Reference (23)：

• 1. Adelfinger, M., Gentschev, I., Grimm de Guibert, J., Weibel, S., Langbein-Laugwitz, J., Härtl, B., Murua Escobar, H., Nolte, I., Chen, N. G., Aguilar, R. J., Yu, Y. A., Zhang, Q., Frentzen, A. and Szalay, A. A. 2014. Evaluation of a new recombinant oncolytic vaccinia virus strain GLV-5b451 for feline mammary carcinoma therapy. PLoS ONE 9: e104337.
• 2. Bergers, G. and Benjamin, L. E. 2003. Tumorigenesis and the angiogenic switch. Nat. Rev. Cancer 3: 401-410.
• 3. Borrego, J. F., Cartagena, J. C. and Engel, J. 2009. Treatment of feline mammary tumours using chemotherapy, surgery and a COX-2 inhibitor drug (meloxicam): a retrospective study of 23 cases (2002-2007). Vet. Comp. Oncol. 7: 213-221.
• 4. de Vries, C., Escobedo, J. A., Ueno, H., Houck, K., Ferrara, N. and Williams, L. T. 1992. The fms-like tyrosine kinase, a receptor for vascular endothelial growth factor. Science 255: 989-991.
• 5. Ferrara, N. 2001. Role of vascular endothelial growth factor in regulation of physiological angiogenesis. Am. J. Physiol. Cell Physiol. 280: C1358-C1366.

Terms in the title (6)： ネコ科 ,  乳癌 ,  異種移植 ,  モデル ,  ベバシズマブ ,  抗腫瘍作用