Art

J-GLOBAL ID：201602280559755035   Reference number：16A1271980

Corticosterone Inhibits the Proliferation of C6 Glioma Cells via the Translocation of Unphosphorylated Glucocorticoid Receptor

コルチコステロンは非リン酸化グルココルチコイド受容体の移行を介してC6グリオーマ細胞の増殖を阻害する

Author (4)： Nakatani Yoshihiko (Department of Pharmacology, School of Pharmacy, International University of Health and Welfare) ,  Nakatani Yoshihiko (Department of Pharmacotherapeutics, School of Pharmacy, International University of Health and Welfare) ,  Amano Taku (Department of Pharmacotherapeutics, School of Pharmacy, International University of Health and Welfare) ,  Takeda Hiroshi (Department of Pharmacology, School of Pharmacy, International University of Health and Welfare)
Material： Biological and Pharmaceutical Bulletin  (Biological & Pharmaceutical Bulletin)
Volume： 39  Issue： 7  Page： 1121-1129(J-STAGE)  Publication year： 2016 
JST Material Number： S0989A  ISSN： 0918-6158  CODEN： BPBLEO  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： cultured cell ,...
Semi thesaurus term： C6 glioma cell ,...

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Author keywords (10)： corticosterone ,  phosphorylation ,  glucocorticoid ,  mineralocorticoid ,  C6 glioma cell ,  corticosterone ,  phosphorylation ,  glucocorticoid ,  mineralocorticoid ,  C6 glioma cell

JST classification (1)： Basic neurology  (GN01020W)

Substance index (2)： Corticosterone ,  Mifepristone

Reference (35)：

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• 2) Dittmar KD, Demady DR, Stancato LF, Krishna P, Pratt WB. Folding of the glucocorticoid receptor by the heat shock protein (hsp) 90-based chaperone machinery. The role of p23 is to stabilize receptor·hsp90 heterocomplexes formed by hsp90·p60·hsp70. J. Biol. Chem., 272, 21213-21220 (1997).
• 3) Dittmar KD, Banach M, Galigniana MD, Pratt WB. The role of DnaJ-like proteins in glucocorticoid receptor·hsp90 heterocomplex assembly by the reconstituted hsp90·p60·hsp70 foldosome complex. J. Biol. Chem., 273, 7358-7366 (1998).
• 4) Nissen RM, Yamamoto KR. The glucocorticoid receptor inhibits NFkappaB by interfering with serine-2 phosphorylation of the RNA polymerase II carboxy-terminal domain. Genes Dev., 14, 2314-2329 (2000).
• 5) Krstic MD, Rogatsky I, Yamamoto KR, Garabedian MJ. Mitogen-activated and cyclin-dependent protein kinases selectively and differentially modulate transcriptional enhancement by the glucocorticoid receptor. Mol. Cell. Biol., 17, 3947-3954 (1997).

Terms in the title (7)： コルチコステロン ,  リン酸化 ,  グルココルチコイド受容体 ,  移行 ,  C6グリオーマ細胞 ,  増殖 ,  阻害