Art

J-GLOBAL ID：201602281067553484   Reference number：16A0322111

A humanized neutralizing antibody against MERS-CoV targeting the receptor-binding domain of the spike protein

スパイク蛋白質の受容体結合ドメインを標的とするMERS-CoVに対するヒト中和抗体【Powered by NICT】

Author (15)： Li Yan (Inst. of Microbiology, Chinese Acad. of Sciences CAS Key Lab. of Pathogenic Microbiology and ...) ,  Wan Yuhua (Inst. of Microbiology, Chinese Acad. of Sciences CAS Key Lab. of Pathogenic Microbiology and ...) ,  Liu Peipei (Inst. of Microbiology, Chinese Acad. of Sciences CAS Key Lab. of Pathogenic Microbiology and ...) ,  Zhao Jincun (Departments of Microbiology and Pediatrics, Univ. of Iowa, USA, Iowa City) ,  Lu Guangwen (West China Hospital, West China Medical School, Sichuan Univ. State Key Lab. of Biotherapy and Cancer Center ...) ,  Qi Jianxun (Inst. of Microbiology, Chinese Acad. of Sciences CAS Key Lab. of Pathogenic Microbiology and ...) ,  Wang Qihui (Inst. of Microbiology, Chinese Acad. of Sciences CAS Key Lab. of Microbial and Metabolic engineering, Beijing) ,  Lu Xuancheng (Lab. Animal Center, Chinese Center for Disease Control and Prevention (China CDC), Beijing) ,  Wu Ying (Inst. of Microbiology, Chinese Acad. of Sciences CAS Key Lab. of Pathogenic Microbiology and ...) ,  Liu Wenjun (Inst. of Microbiology, Chinese Acad. of Sciences CAS Key Lab. of Pathogenic Microbiology and ...) ,  Zhang Buchang (School of Life Sciences, Anhui Univ., Anhui, Hefei) ,  Yuen Kwokyung (Dep. of Microbiology, The Univ. of Hong Kong State Key Lab. for Emerging Infectious Diseases, Hong Kong) ,  Perlman Stanley (Departments of Microbiology and Pediatrics, Univ. of Iowa, USA, Iowa City) ,  Gao George F (Inst. of Microbiology, Chinese Acad. of Sciences CAS Key Lab. of Pathogenic Microbiology and ...) ,  Yan Jinghua (Inst. of Microbiology, Chinese Acad. of Sciences CAS Key Lab. of Pathogenic Microbiology and ...)
Material： Cell Research  (Cell Res)
Volume： 25  Issue： 11  Page： 1237-1249  Publication year： 2015 
JST Material Number： C2561A  ISSN： 1001-0602  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Abstract/Point： The newly-emerging Middle East...

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Thesaurus term： antiviral drug ,  *neutralizing antibody ,  *neutralization ,  *binding site ,  monoclonal antibody ,  transduction ,  immunity ,  amino acid ,  epitope ,  in vitro experiment ,  lung ,  *human(primates) ,  virus ,  *receptor
Semi thesaurus term： *受容体結合 , 【Automatic Indexing@JST】

JST classification (1)： Cell physiology in general  (EF02010S)

Terms in the title (6)： スパイク蛋白質 ,  受容体結合 ,  ドメイン ,  標的 ,  ヒト ,  中和抗体