Art

J-GLOBAL ID：201602284122129767   Reference number：16A1051665

Screening, expression, and characterization of an anti-human oxidized low-density lipoprotein single-chain variable fragment

抗ヒト酸化低密度リポ蛋白質一本鎖可変断片のスクリーニング,発現と特徴化

Author (5)： Kumano-Kuramochi Miyuki (National Food Research Institute, NARO, 2-1-12 Kannondai, Tsukuba, Ibaraki 305-8642, Japan) ,  Fujimura Takashi (National Food Research Institute, NARO, 2-1-12 Kannondai, Tsukuba, Ibaraki 305-8642, Japan) ,  Komba Shiro (National Food Research Institute, NARO, 2-1-12 Kannondai, Tsukuba, Ibaraki 305-8642, Japan) ,  Maeda-Yamamoto Mari (National Food Research Institute, NARO, 2-1-12 Kannondai, Tsukuba, Ibaraki 305-8642, Japan) ,  Machida Sachiko (National Food Research Institute, NARO, 2-1-12 Kannondai, Tsukuba, Ibaraki 305-8642, Japan)
Material： Journal of Bioscience and Bioengineering
Volume： 122  Issue： 3  Page： 287-293  Publication year： Sep. 2016 
JST Material Number： G0535B  ISSN： 1389-1723  CODEN： JBBIF6  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Thesaurus term： *LDL ,...
Semi thesaurus term： *oxidized low density lipoprotein ,...

Register(free) or Log In to access     To see more with JDream III (charged).   {{ this.onShowAbsJLink("http://jdream3.com/lp/jglobal/index.html?docNo=16A1051665&from=J-GLOBAL&jstjournalNo=G0535B") }}

Author keywords (6)： Key words Single-chain variable fragment ,  Phage display library ,  Low-density lipoprotein ,  Oxidized low-density lipoprotein ,  Enzyme-linked immunosorbent assay ,  Protein refolding

JST classification (3)： Animal biochemistry  (EJ01050P) ,  Proteins and peptides in general  (EB03010N) ,  Gene expression  (EC02040Q)

Reference (32)：

• Brown, M. S. and Goldstein, J. L.: Lipoprotein metabolism in the macrophage: implications for cholesterol deposition in atherosclerosis, Annu. Rev. Biochem., 52, 223-261 (1983).
• Steinberg, D., Parthasarathy, S., Carew, T. E., Khoo, J. C., and Witztum, J. L.: Beyond cholesterol. Modifications of low-density lipoprotein that increase its atherogenicity, N. Engl. J. Med., 320, 915-924 (1989).
• Kita, T., Nagano, Y., Yokode, M., Ishii, K., Kume, N., Ooshima, A., Yoshida, H., and Kawai, C.: Probucol prevents the progression of atherosclerosis in Watanabe heritable hyperlipidemic rabbit, an animal model for familial hypercholesterolemia, Proc. Natl. Acad. Sci. USA, 84, 5928-5931 (1987).
• Yla-Herttuala, S., Palinski, W., Rosenfeld, M. E., Parthasarathy, S., Carew, T. E., Butler, S., Witztum, J. L., and Steinberg, D.: Evidence for the presence of oxidatively modified low density lipoprotein in atherosclerotic lesions of rabbit and man, J. Clin. Invest., 84, 1086-1095 (1989).
• Toshima, S., Hasegawa, A., Kurabayashi, M., Itabe, H., Takano, T., Sugano, J., Shimamura, K., Kimura, J., Michishita, I., Suzuki, T., and Nagai, R.: Circulating oxidized low density lipoprotein levels. A biochemical risk marker for coronary heart disease, Arterioscler. Thromb. Vasc. Biol., 20, 2243-2247 (2000).

Terms in the title (6)： ヒト ,  酸化低密度リポ蛋白質 ,  可変 ,  断片 ,  スクリーニング ,  発現