Art

J-GLOBAL ID：201602286817588114   Reference number：16A1380180

L-Theanine protects against excess dopamine-induced neurotoxicity in the presence of astrocytes

L-テアニンは星状細胞存在下での過剰ドーパミン誘導の神経毒性を保護する

Author (9)： Takeshima Mika (Department of Brain Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences) ,  Miyazaki Ikuko (Department of Brain Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences) ,  Miyazaki Ikuko (Department of Medical Neurobiology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences) ,  Murakami Shinki (Department of Brain Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences) ,  Murakami Shinki (Department of Medical Neurobiology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences) ,  Murakami Shinki (SAIDO Co.) ,  Kita Taizo (Laboratory of Pharmacology, Kyushu Nutrition Welfare University School of Health Science) ,  Asanuma Masato (Department of Brain Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences) ,  Asanuma Masato (Department of Medical Neurobiology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences)
Material： Journal of Clinical Biochemistry and Nutrition  (JCBN)
Volume： 59  Issue： 2  Page： 93-99  Publication year： 2016 
JST Material Number： X0851A  ISSN： 0912-0009  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： Mesencephalon ,...
Semi thesaurus term： cell physiology ,...

Register(free) or Log In to access     To see more with JDream III (charged).   {{ this.onShowAbsJLink("http://jdream3.com/lp/jglobal/index.html?docNo=16A1380180&from=J-GLOBAL&jstjournalNo=X0851A") }}

Author keywords (5)： L-theanine ,  dopamine ,  astrocyte ,  glutathione ,  neuroprotection

JST classification (2)： Basic research of other drugs acting on central nervous system  (GW03120U) ,  Basic neurology  (GN01020W)

Substance index (3)： Theanine ,  Glutathione ,  Dopamine

Reference (40)：

• 1 Kimura R, Murata T. Influence of alkylamides of glutamic acid and related compounds on the central nervous system. II. Syntheses of amides of gutamic acid and related compounds, and their effects on the central nervous system. Chem Pharm Bull (Tokyo) 1971; 19: 1301-1307.
• 2 Yokogoshi H, Kato Y, Sagesaka YM, Takihara-Matsuura T, Kakuda T, Takeuchi N. Reduction effect of theanine on blood pressure and brain 5-hydroxyindoles in spontaneously hypertensive rats. Biosci Biotechnol Biochem 1995; 59: 615-618.
• 3 Nishida K, Yasuda E, Nagasawa K, Fujimoto S. Altered levels of oxidation and phospholipase C isozyme expression in the brains of theanine-administered rats. Biol Pharm Bull 2008; 31: 857-860.
• 4 Yokozawa T, Dong E. Influence of green tea and its three major components upon low-density lipoprotein oxidation. Exp Toxicol Pathol 1997; 49: 329-335.
• 5 Terashima T, Takido J, Yokogoshi H. Time-dependent changes of amino acids in the serum, liver, brain and urine of rats administered with theanine. Biosci Biotechnol Biochem 1999; 63: 615-618.

Terms in the title (5)： L-テアニン ,  星状細胞 ,  ドーパミン ,  誘導 ,  神経毒性