Art

J-GLOBAL ID：201602286817588114   Reference number：16A1380180

L-Theanine protects against excess dopamine-induced neurotoxicity in the presence of astrocytes

L-テアニンは星状細胞存在下での過剰ドーパミン誘導の神経毒性を保護する

Author (9)： Takeshima Mika (Department of Brain Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences) ,  Miyazaki Ikuko (Department of Brain Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences) ,  Miyazaki Ikuko (Department of Medical Neurobiology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences) ,  Murakami Shinki (Department of Brain Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences) ,  Murakami Shinki (Department of Medical Neurobiology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences) ,  Murakami Shinki (SAIDO Co.) ,  Kita Taizo (Laboratory of Pharmacology, Kyushu Nutrition Welfare University School of Health Science) ,  Asanuma Masato (Department of Brain Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences) ,  Asanuma Masato (Department of Medical Neurobiology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences)
Material： Journal of Clinical Biochemistry and Nutrition  (JCBN)
Volume： 59  Issue： 2  Page： 93-99  Publication year： 2016 
JST Material Number： X0851A  ISSN： 0912-0009  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： mesencephalon ,...
Semi thesaurus term： quinoprotein ,...

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Author keywords (5)： L-theanine ,  dopamine ,  astrocyte ,  glutathione ,  neuroprotection

JST classification (2)： Basic research of other drugs acting on central nervous system  (GW03120U) ,  Basic neurology  (GN01020W)

Substance index (3)： Theanine ,  Glutathione ,  Dopamine

Reference (40)：

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• 2 Yokogoshi H, Kato Y, Sagesaka YM, Takihara-Matsuura T, Kakuda T, Takeuchi N. Reduction effect of theanine on blood pressure and brain 5-hydroxyindoles in spontaneously hypertensive rats. Biosci Biotechnol Biochem 1995; 59: 615-618.
• 3 Nishida K, Yasuda E, Nagasawa K, Fujimoto S. Altered levels of oxidation and phospholipase C isozyme expression in the brains of theanine-administered rats. Biol Pharm Bull 2008; 31: 857-860.
• 4 Yokozawa T, Dong E. Influence of green tea and its three major components upon low-density lipoprotein oxidation. Exp Toxicol Pathol 1997; 49: 329-335.
• 5 Terashima T, Takido J, Yokogoshi H. Time-dependent changes of amino acids in the serum, liver, brain and urine of rats administered with theanine. Biosci Biotechnol Biochem 1999; 63: 615-618.

Terms in the title (5)： L-テアニン ,  星状細胞 ,  ドーパミン ,  誘導 ,  神経毒性