Art

J-GLOBAL ID：201602298232106694   Reference number：16A0594279

PTP1B controls non-mitochondrial oxygen consumption by regulating RNF213 to promote tumour survival during hypoxia

PTP1Bは酸素欠乏時の腫瘍生存を生起するためにRNF213を制御することにより非ミトコンドリア酸素消費を調節する

Author (36)： BANH Robert S. (Univ. Toronto, Ontario, CAN) ,  BANH Robert S. (Univ. Health Network, Ontario, CAN) ,  BANH Robert S. (New York Univ., New York, USA) ,  IORIO Caterina (Univ. Health Network, Ontario, CAN) ,  MARCOTTE Richard (Univ. Health Network, Ontario, CAN) ,  XU Yang (Univ. Toronto, Ontario, CAN) ,  XU Yang (Univ. Health Network, Ontario, CAN) ,  XU Yang (New York Univ., New York, USA) ,  COJOCARI Dan (Univ. Toronto, Ontario, CAN) ,  COJOCARI Dan (Univ. Health Network, Ontario, CAN) ,  RAHMAN Anas Abdel (Mount Sinai Hospital, Ontario, CAN) ,  RAHMAN Anas Abdel (King Faisal Specialist Hospital and Res. Center, Riyadh, SAU) ,  PAWLING Judy (Mount Sinai Hospital, Ontario, CAN) ,  ZHANG Wei (Univ. Toronto, Ontario, CAN) ,  SINHA Ankit (Univ. Toronto, Ontario, CAN) ,  SINHA Ankit (Univ. Health Network, Ontario, CAN) ,  ROSE Christopher M. (Harvard Medical School, Massachusetts, USA) ,  ISASA Marta (Harvard Medical School, Massachusetts, USA) ,  ZHANG Shuang (New York Univ., New York, USA) ,  WU Ronald (Univ. Toronto, Ontario, CAN) ,  WU Ronald (Univ. Health Network, Ontario, CAN) ,  VIRTANEN Carl (Univ. Health Network, Ontario, CAN) ,  HITOMI Toshiaki (Kyoto Univ., Kyoto, JPN) ,  HABU Toshiyuki (Kyoto Univ., Kyoto, JPN) ,  SIDHU Sachdev S. (Univ. Toronto, Ontario, CAN) ,  KOIZUMI Akio (Kyoto Univ., Kyoto, JPN) ,  WILKINS Sarah E. (Oxford Univ., Oxford, GBR) ,  KISLINGER Thomas (Univ. Toronto, Ontario, CAN) ,  KISLINGER Thomas (Univ. Health Network, Ontario, CAN) ,  GYGI Steven P. (Harvard Medical School, Massachusetts, USA) ,  SCHOFIELD Christopher J. (Oxford Univ., Oxford, GBR) ,  DENNIS James W. (Mount Sinai Hospital, Ontario, CAN) ,  WOUTERS Bradly G. (Univ. Toronto, Ontario, CAN) ,  WOUTERS Bradly G. (Univ. Health Network, Ontario, CAN) ,  NEEL Benjamin G. (Univ. Health Network, Ontario, CAN) ,  NEEL Benjamin G. (New York Univ., New York, USA)
Material： Nature Cell Biology  (Nat Cell Biol)
Volume： 18  Issue： 7  Page： 803-813  Publication year： Jul. 2016 
JST Material Number： W1369A  ISSN： 1465-7392  Document type： Article
Article type： 短報  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Thesaurus term： *cytoplasmic-type tyrosine phosphatase ,  *breast tumor ,  *oxygen deficiency ,  tumor process ,  protein ,  substrate(biochemistry) ,  mouse(animal) ,  experimental disease ,  cell physiology ,  oxygen consumption ,  metabolism ,  biological activity ,  cellular signal transduction
Semi thesaurus term： Her2 positive breast cancer ,  *PTP1B ,  RNF213蛋白質 ,  enzyme substrate ,  Tumor Microenvironment ,  tissue oxygen metabolism ,  cancer bearing mouse

JST classification (3)： Chemistry,biochemistry and pathology of tumors(=neoplasms)  (GE02030N) ,  Cell physiology in general  (EF02010S) ,  Biological function  (EB03040U)

Terms in the title (8)： PTP1B ,  酸素欠乏 ,  腫瘍 ,  生存 ,  生起 ,  ミトコンドリア ,  酸素消費 ,  調節