Rchr
J-GLOBAL ID：201701001960330541   Update date: Jul. 28, 2024

Kanai Ryuta

Kanai Ryuta
Affiliation and department：
The University of Tokyo Institute of Molecular and Cellular Biosciences

About The University of Tokyo Institute of Molecular and Cellular Biosciences


Research field  (1)： Structural biochemistry
Research theme for competitive and other funds  (10)：
  • 2023 - 2026 イオンポンプ蛋白質作動機構の構造的理解の完成とその高次機能の構造生物学への発展
  • 2023 - 2025 Development of artificial reaction intermediates by introduction of steric hindrance
  • 2021 - 2024 Na+,K+-ATPaseによるK+選択的結合機構の構造生物学的研究
  • 2019 - 2022 Structural biology of active transport and its regulation by P-type ATPases
  • 2018 - 2022 Structural basis for Na+-selectivity of the sodium pump
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Papers (28)：
  • Takaharu Sakuragi, Ryuta Kanai, Mayumi Otani, Masahide Kikkawa, Chikashi Toyoshima, Shigekazu Nagata. The role of the C-terminal tail region as a plug to regulate XKR8 lipid scramblase. The Journal of biological chemistry. 2024. 300. 3. 105755-105755
  • Ryuta Kanai, Bente Vilsen, Flemming Cornelius, Chikashi Toyoshima. Crystal structures of Na+ ,K+ -ATPase reveal the mechanism that converts the K+ -bound form to Na+ -bound form and opens and closes the cytoplasmic gate. FEBS letters. 2023
  • Xingya Xu, Ryuta Kanai, Li Wang, Mitsuhiro Yanagida. Cohesin ATPase activities regulate DNA binding and coiled-coil configuration. Proceedings of the National Academy of Sciences of the United States of America. 2022. 119. 33. e2208004119
  • Ryuta Kanai, Flemming Cornelius, Bente Vilsen, Chikashi Toyoshima. Cryo-electron microscopy of Na+ ,K+ -ATPase reveals how the extracellular gate locks in the E2·2K+ state. FEBS letters. 2022
  • Ryuta Kanai, Flemming Cornelius, Bente Vilsen, Chikashi Toyoshima. Cryoelectron microscopy of Na+,K+-ATPase in the two E2P states with and without cardiotonic steroids. Proceedings of the National Academy of Sciences of the United States of America. 2022. 119. 15. e2123226119
ｍore...
Education (2)：
  • 2000 - 2004 University of Tsukuba
  • 1996 - 2000 University of Tsukuba
Professional career (1)：
  • 博士(理学) (筑波大学)
Work history (8)：
  • 2023/05 - 現在 The University of Tokyo
  • 2020/04 - 2023/04 The University of Tokyo
  • 2018/04 - 2020/03 The University of Tokyo
  • 2010/07 - 2018/03 The University of Tokyo Institute of Molecular and Cellular Biosciences
  • 2009/04 - 2010/06 Yale University (USA) Dept. of Molecular Biophysics and Biochemistry
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